| Project/Area Number |
23K14256
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 45030:Biodiversity and systematics-related
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| Research Institution | Okinawa Institute of Science and Technology Graduate University |
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Principal Investigator |
HUSNIK Filip 沖縄科学技術大学院大学, 進化・細胞・共生の生物学ユニット, 准教授 (30886130)
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| Project Period (FY) |
2023-04-01 – 2025-03-31
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| Project Status |
Granted (Fiscal Year 2023)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2024: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2023: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | symbiosis / protist / bacteria / archaea / genomics / organelle / evolution / mitochondrion |
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| Outline of Research at the Start |
I will the diversity of symbioses in microbial eukaryotes. I will use advanced single-cell sequencing and microscopy methods to predict the symbiont function(s), uncover their cellular localization, and understand their evolution. The results of the project will clarify the current symbiosis theory and propose new fundamental mechanisms for how symbioses evolve.
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| Outline of Annual Research Achievements |
Our major published achievements so far include work on 7 (6 symbiont-derived) genomes in a single cryptomonad cell (George et al., Cur Biol 2023) and a study showing that previously reported symbionts in Symbiomonas were misidentified giant viruses (Cho et al., PLoS Genetics, 2024).
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| Current Status of Research Progress |
Current Status of Research Progress
1: Research has progressed more than it was originally planned.
Reason
Due to the solid preparation status with many samples already collected or cultured in my group, the initial plan to screen a diversity of protists for symbionts is largely finished.
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| Strategy for Future Research Activity |
In the FY2024, we will proceed with a detailed characterization of the selected systems. So far, we published our work on 2 species (Cryptomonas and Symbiomonas). A manuscript on 7 species of large benthic foraminifera is currently drafted and additional manuscripts on >5 systems are in preparation. We will thus reach the number of ~10 characterized systems as proposed in the application.
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