Development of noninvasive neuromodulation techniques to enhance resilience to depression

• Project/Area Number: 23K14819
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 52030:Psychiatry-related
• Research Institution: Hiroshima University
• Principal Investigator: CHAN HUILING 広島大学, 脳・こころ・感性科学研究センター, 特任助教 (80867979)
• Project Period (FY): 2023-04-01 – 2027-03-31
• Project Status: Granted (Fiscal Year 2023)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2026: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000); Fiscal Year 2025: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2024: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2023: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: vagus nerve stimulation / depression / resilience / interoception / neuroimaging

Outline of Research at the Start

Interoception deficits have been related to low resilience and high depression. TaVNS has been shown to modulate interoceptive system. However, effects of taVNS on preventing depression is unclear. This research aims at developing taVNS-based techniques to improve resilience and reduce depression.