Mechano-geometrical cell interface for generating hiPSC derived higher order gastruloid

Research Project

Project/Area Number	23K17205
Research Category	Grant-in-Aid for Early-Career Scientists
Allocation Type	Multi-year Fund
Review Section	Basic Section 90110:Biomedical engineering-related
Research Institution	Institute of Physical and Chemical Research
Principal Investigator	Vadivelu RajaKumar 国立研究開発法人理化学研究所, 開拓研究本部, 基礎科学特別研究員 (60963543)
Project Period (FY)	2023-04-01 – 2025-03-31
Project Status	Granted (Fiscal Year 2023)
Budget Amount *help	¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000) Fiscal Year 2024: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000) Fiscal Year 2023: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords	IPSCs / Gastruloid / Mechanobiology / Morphogenesis / Organogenesis
Outline of Research at the Start	The research capture the ability of cell-material interface to induce morphogenetic processes and emergence on early organogenesis in gastruloid without exogenous stimulation.