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Identification of modifiable factors for cognitive decline: use of multimodal biological data.

Research Project

Project/Area Number 23K21863
Project/Area Number (Other) 21H03851 (2021-2023)
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeMulti-year Fund (2024)
Single-year Grants (2021-2023)
Section一般
Review Section Basic Section 90150:Medical assistive technology-related
Research InstitutionShiga University of Medical Science

Principal Investigator

角谷 寛  滋賀医科大学, 医学部, 特任教授 (90362516)

Co-Investigator(Kenkyū-buntansha) 藤原 幸一  名古屋大学, 工学研究科, 准教授 (10642514)
角 幸頼  滋賀医科大学, 医学部, 客員助教 (10772923)
加納 学  京都大学, 情報学研究科, 教授 (30263114)
大道 智恵  同志社大学, 研究開発推進機構, 助教 (30907944)
須藤 智志  滋賀医科大学, 医学部, 客員助手 (70897917)
Project Period (FY) 2021-04-01 – 2025-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2024: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2023: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2022: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2021: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords軽度認知障害 / レム睡眠行動障害 / 活動量 / コホート研究 / 心拍 / 認知機能障害 / 機械学習 / 睡眠障害 / 認知症 / 心拍変動 / 認知機能低下 / 早期発見 / リスク因子
Outline of Research at the Start

簡便に取得できるマルチモーダルな生体データを統合的に解析することで、認知機能低下の客観的指標の確立を目指す。そのために、アルツハイマー病およびレビー小体型認知症という有病率の高い二つの認知症のハイリスク群および健常高齢者群を対象に、認知機能および生体データについてベースライン調査並びに追跡調査を実施し、機械学習の手法を用いて認知機能低下のリスク因子を同定する。

Outline of Annual Research Achievements

所属研究機関の研究活動制限により、外来患者及び健康な高齢者の生体データ取得が出来なくなり、予定していたベースライン調査(生体データ取得、認知機能評価、生体データ解析)を実施することができなかった。
そこで、疫学データ及び既存データを用いた解析を行った。その結果、特に、レビー小体型認知症の前駆症状として注目しているレム睡眠行動障害については、うつ病との関係に関するシステマティックレビューを行うとともに、多施設共同研究の結果を報告した。また、在宅・高齢者対象でも取得・解析が可能な生体データである心拍/心拍変動や、簡易な1CHの脳波計により取得した睡眠脳波のデータを元に機械学習等を用いた解析も実施した。これらの成果は今後実施予定のベースライン調査においても有用と考えられる。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

所属研究機関の研究活動制限により、外来患者及び健康な高齢者の生体データ取得が出来なくなり、予定していたベースライン調査(生体データ取得、認知機能評価、生体データ解析)を実施することができなかった。しかし、その間に実施した既存データ及び疫学研究の解析にの結果、特に、レビー小体型認知症の前駆症状として注目しているレム睡眠行動障害については、うつ病との関係に関するシステマティックレビューを行うとともに、多施設共同研究の結果を報告した。

Strategy for Future Research Activity

所属研究機関の制限解除が見込まれる時点で再度日程調整し、その後ベースライン調査を実施する。それまでは既存データおよび疫学データを用いた解析を行い、その結果をベースライン調査に活用する。

Report

(2 results)
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • Research Products

    (71 results)

All 2022 2021 Other

All Int'l Joint Research (7 results) Journal Article (29 results) (of which Int'l Joint Research: 3 results,  Open Access: 20 results,  Peer Reviewed: 22 results) Presentation (32 results) (of which Int'l Joint Research: 8 results,  Invited: 7 results) Book (3 results)

  • [Int'l Joint Research] Durham University, Durham(英国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Swinburne University of Technology/University of Sydney(オーストラリア)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] Monash Medical Centre(オーストリア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Himalayan Institute of Medical Sciences(インド)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] Universidad Peruana Cayetano Heredia(ペルー)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] National Research Council of Italy(イタリア)

    • Related Report
      2021 Annual Research Report
  • [Int'l Joint Research] National University of Colombia(コロンビア)

    • Related Report
      2021 Annual Research Report
  • [Journal Article] 特集 中枢性自律神経障害update 睡眠障害と自律神経障害2022

    • Author(s)
      角 幸頼、角谷 寛
    • Journal Title

      BRAIN and NERVE

      Volume: 74 Issue: 3 Pages: 279-282

    • DOI

      10.11477/mf.1416202024

    • ISSN
      1344-8129, 1881-6096
    • Year and Date
      2022-03-01
    • Related Report
      2022 Annual Research Report
    • Open Access
  • [Journal Article] Japanese clinical guideline for sleep apnea syndrome (SAS)2022

    • Author(s)
      Kadotani Hiroshi
    • Journal Title

      Sleep and Biological Rhythms

      Volume: 20 Issue: 1 Pages: 3-3

    • DOI

      10.1007/s41105-021-00358-1

    • NAID

      120007175592

    • Related Report
      2022 Annual Research Report
    • Open Access
  • [Journal Article] Editorial: The impact of social isolation and loneliness on mental health and wellbeing2022

    • Author(s)
      Kadotani Hiroshi、Okajima Isa、Yang Keming、Lim Michelle H.
    • Journal Title

      Frontiers in Public Health

      Volume: 10 Pages: 1-13

    • DOI

      10.3389/fpubh.2022.1106216

    • Related Report
      2022 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Prolonged Sleep Latency and Reduced REM Latency Are Associated with Depressive Symptoms in a Japanese Working Population2022

    • Author(s)
      Omichi Chie、Kadotani Hiroshi、Sumi Yukiyoshi、Ubara Ayaka、Nishikawa Kohei、Matsuda Arichika、Ozeki Yuji、the NinJaSleep Study Group
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 19 Issue: 4 Pages: 2112-2112

    • DOI

      10.3390/ijerph19042112

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Minor hallucinations as risk factor of early phenoconversion in patients with idiopathic rapid eye movement sleep behavior disorder.2022

    • Author(s)
      Sumi, Y., Ubara, A., Ozeki, Y., & Kadotani, H.
    • Journal Title

      Acta Neurologica Scandinavica

      Volume: 145 Issue: 3 Pages: 348-359

    • DOI

      10.1111/ane.13555

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Associations of nonrestorative sleep and insomnia symptoms with incident depressive symptoms over 1-2 years: longitudinal results from the Hispanic Community Health Study/Study of Latinos and Sueno Ancillary Study2022

    • Author(s)
      Saitoh K, Yoshiike T, Kaneko Y, Utsumi T, Matsui K, Nagao K, Otsuki R, Aritake S, Kadotani H, Kuriyama K, Suzuki M
    • Journal Title

      Depression and Anxiety

      Volume: - Issue: 5 Pages: 419-428

    • DOI

      10.1002/da.23258

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Obstructive Sleep Apnoea Severity Is Negatively Associated with Depressive Symptoms: A Cross-Sectional Survey of Outpatients with Suspected Obstructive Sleep Apnoea in Japan2022

    • Author(s)
      Ito Kazuki、Uetsu Masahiro、Ubara Ayaka、Matsuda Arichika、Sumi Yukiyoshi、Kadotani Hiroshi
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 19 Issue: 9 Pages: 5007-5007

    • DOI

      10.3390/ijerph19095007

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Medical checkup data analysis method based on LiNGAM and its application to nonalcoholic fatty liver disease2022

    • Author(s)
      Uchida Tsuyoshi、Fujiwara Koichi、Nishioji Kenichi、Kobayashi Masao、Kano Manabu、Seko Yuya、Yamaguchi Kanji、Itoh Yoshito、Kadotani Hiroshi
    • Journal Title

      Artificial Intelligence in Medicine

      Volume: 128 Pages: 102310-102310

    • DOI

      10.1016/j.artmed.2022.102310

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] R-R interval-based sleep apnea screening by a recurrent neural network in a large clinical polysomnography dataset2022

    • Author(s)
      Iwasaki Ayako、Fujiwara Koichi、Nakayama Chikao、Sumi Yukiyoshi、Kano Manabu、Nagamoto Tetsuharu、Kadotani Hiroshi
    • Journal Title

      Clinical Neurophysiology

      Volume: 139 Pages: 80-89

    • DOI

      10.1016/j.clinph.2022.04.012

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The prevalence of depression in isolated/idiopathic rapid eye movement sleep behavior disorder: A systematic review and meta-analysis.2022

    • Author(s)
      Sumi Y, Masuda F, Kadotani H, Ozeki Y.
    • Journal Title

      Sleep Med Rev

      Volume: 65 Pages: 101684-101684

    • DOI

      10.1016/j.smrv.2022.101684

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Idiopathic rapid eye movement sleep behavior disorder in Japan: An observational study2022

    • Author(s)
      Nishikawa N、Murata M、Hatano T、Mukai Y、Saitoh Y、Sakamoto T、Hanakawa T、Kamei Y、Tachimori H、Hatano K、Matsuda H、Taruno Y、Sawamoto N、Kajiyama Y、Ikenaka K、Kawabata K、Nakamura T、Iwaki H、Kadotani H、Sumi Y、Inoue Y、Hayashi T、Ikeuchi T、Shimo Y、Mochizuki H、Watanabe H、Hattori N、Takahashi Y、Takahashi R
    • Journal Title

      Parkinsonism & Related Disorders

      Volume: 103 Pages: 129

    • DOI

      10.1016/j.parkreldis.2022.08.011

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of pleasant sound on overnight sleep condition: A crossover randomized study2022

    • Author(s)
      Saeda Shota、Fujiwara Koichi、Kinoshita Takafumi、Sumi Yukiyoshi、Matsuo Masahiro、Yamaki Kiyoshi、Kawashima Takahiro、Kadotani Hiroshi
    • Journal Title

      Frontiers in Sleep

      Volume: 1 Pages: 1-1

    • DOI

      10.3389/frsle.2022.986333

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sleep-EEG-based parameters for discriminating fatigue and sleepiness2022

    • Author(s)
      Fujiwara Koichi、Goto Yuki、Sumi Yukiyoshi、Kano Manabu、Kadotani Hiroshi
    • Journal Title

      Frontiers in Sleep

      Volume: 1 Pages: 1-1

    • DOI

      10.3389/frsle.2022.975415

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Limited social support is associated with depression, anxiety, and insomnia in a Japanese working population.2022

    • Author(s)
      Omichi C, Kaminishi Y, Kadotani H, Sumi Y, Ubara A, Nishikawa K, Matsuda A, Ozeki Y.
    • Journal Title

      Front Public Health

      Volume: 21 Pages: 981592-981592

    • DOI

      10.3389/fpubh.2022.981592

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Irregular sleep and all-cause mortality: A large prospective cohort study2022

    • Author(s)
      Omichi C., Koyama T., Kadotani H., Ozaki E., Tomida S., Yoshida T., Otonari J., Ikezaki H., Hara M., et al.
    • Journal Title

      Sleep Health

      Volume: 8 Issue: 6 Pages: 678-683

    • DOI

      10.1016/j.sleh.2022.08.010

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【2022年 医療展望】不眠症 COVID-19が人々の生活スタイルと心理に与えた影響2022

    • Author(s)
      角谷寛.
    • Journal Title

      クリニシアン

      Volume: 69 Pages: 8-13

    • Related Report
      2022 Annual Research Report
  • [Journal Article] 【高齢患者の精神科コンサルテーション・リエゾン(CLP)】身体疾患に伴う不眠2022

    • Author(s)
      角谷寛.
    • Journal Title

      老年精神医学

      Volume: 33 Pages: 25-28

    • Related Report
      2022 Annual Research Report
  • [Journal Article] 【睡眠呼吸障害(SDB)と認知症】SDBの認知症への影響 初期の認知機能低下とSDB2022

    • Author(s)
      松田有史, 角谷寛.
    • Journal Title

      睡眠医療

      Volume: 16 Pages: 151-154

    • Related Report
      2022 Annual Research Report
  • [Journal Article] 縁が絆ぐ ねむりの世界2022

    • Author(s)
      角谷寛.
    • Journal Title

      Journal of Oral and Sleep Medicine

      Volume: 9 Issue: 1 Pages: 1-1

    • DOI

      10.24695/josm.9.1_1

    • ISSN
      2188-6695, 2433-8524
    • Related Report
      2022 Annual Research Report
    • Open Access
  • [Journal Article] Correlation of Antidepressant Use and Symptom Time Period in Dream Enactment Behaviors2021

    • Author(s)
      Sumi Yukiyoshi、Kadotani Hiroshi、Ozeki Yuji
    • Journal Title

      Movement Disorders Clinical Practice

      Volume: 9 Issue: 1 Pages: 130-131

    • DOI

      10.1002/mdc3.13378

    • NAID

      120007180663

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association between discontinuation of benzodiazepine receptor agonists and post-operative delirium among inpatients with liaison intervention: A retrospective cohort study2021

    • Author(s)
      Omichi Chie、Ayani Nobutaka、Oya Nozomu、Matsumoto Yoshihiro、Tanaka Maki、Morimoto Takeshi、Kadotani Hiroshi、Narumoto Jin
    • Journal Title

      Comprehensive Psychiatry

      Volume: 104 Pages: 152216-152216

    • DOI

      10.1016/j.comppsych.2020.152216

    • NAID

      120007159524

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Endorsement of: “clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American academy of sleep medicine clinical practice guideline” by the World Sleep Society2021

    • Author(s)
      Hamilton Garun S.、Gupta Ravi、Vizcarra Darwin、Insalaco Giuseppe、Escobar Franklin、Kadotani Hiroshi
    • Journal Title

      Sleep Medicine

      Volume: 79 Pages: 152-154

    • DOI

      10.1016/j.sleep.2020.12.044

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effects of Cognitive Behavioral Therapy for Insomnia on Subjective?Objective Sleep Discrepancy in Patients with Primary Insomnia: a Small-Scale Cohort Pilot Study2021

    • Author(s)
      Nishikawa Kohei、Kuriyama Kenichi、Yoshiike Takuya、Yoshimura Atsushi、Okawa Masako、Kadotani Hiroshi、Yamada Naoto
    • Journal Title

      International Journal of Behavioral Medicine

      Volume: 24 Issue: 6 Pages: 1-12

    • DOI

      10.1007/s12529-021-09969-x

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Large Questionnaire Survey on Sleep Duration and Insomnia Using the TV Hybridcast System by Japan Broadcasting Corporation (NHK)2021

    • Author(s)
      Ito Kazuki、Kadotani Hiroshi、Okajima Isa、Ubara Ayaka、Ichikawa Mamoru、Omichi Chie、Miyamoto Towa、Matsuda Arichika、Sumi Yukiyoshi、Kitagawa Hirotoshi
    • Journal Title

      International Journal of Environmental Research and Public Health

      Volume: 18 Issue: 5 Pages: 2691-2691

    • DOI

      10.3390/ijerph18052691

    • NAID

      120007000432

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Work Habit-Related Sleep Debt; Insights From Factor Identification Analysis of Actigraphy Data2021

    • Author(s)
      Goto Yuki、Fujiwara Koichi、Sumi Yukiyoshi、Matsuo Masahiro、Kano Manabu、Kadotani Hiroshi
    • Journal Title

      Frontiers in Public Health

      Volume: 9 Pages: 630640-630640

    • DOI

      10.3389/fpubh.2021.630640

    • NAID

      120007159523

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Factors causing a relapse of major depressive disorders following successful electroconvulsive therapy: A retrospective cohort study2021

    • Author(s)
      Kurimoto Naoki、Inagaki Takahiko、Aoki Takashi、Kadotani Hiroshi、Kurimoto Fujiki、Kuriyama Kenichi、Yamada Naoto、Ozeki Yuji
    • Journal Title

      World Journal of Psychiatry

      Volume: 11 Issue: 10 Pages: 841-853

    • DOI

      10.5498/wjp.v11.i10.841

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Explosive sound without external stimuli following electroencephalography kappa rhythm fluctuation: A case report2021

    • Author(s)
      Sumi Yukiyoshi、Miyamoto Towa、Sudo Satoshi、Kadotani Hiroshi、Ozeki Yuji、Imai Makoto
    • Journal Title

      Cephalalgia

      Volume: 41 Issue: 13 Pages: 1396-1401

    • DOI

      10.1177/03331024211021773

    • NAID

      120007119156

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Screening of sleep apnea based on heart rate variability and long short-term memory2021

    • Author(s)
      Iwasaki Ayako、Nakayama Chikao、Fujiwara Koichi、Sumi Yukiyoshi、Matsuo Masahiro、Kano Manabu、Kadotani Hiroshi
    • Journal Title

      Sleep and Breathing

      Volume: - Issue: 4 Pages: 1-1

    • DOI

      10.1007/s11325-020-02249-0

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 就寝時の「快眠音」が不眠症疑いの労働者への睡眠潜時に与える影響2021

    • Author(s)
      中田ゆかり,柴田英治,角谷寛
    • Journal Title

      厚生の指標(厚生労働統計協会)

      Volume: 68 Pages: 1-7

    • NAID

      40022702695

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Presentation] Sleep Epidemiological Studies with Portable Devices2022

    • Author(s)
      Kadotani H.
    • Organizer
      ISSTA Sleep Science, Technology and Economy OnlineSymposium during World Sleep 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] リエゾン精神医療と睡眠時無呼吸2022

    • Author(s)
      角谷寛
    • Organizer
      第35回 日本総合病院精神医学会総会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 公務員へのソーシャルサポートと不眠・抑うつの関係2022

    • Author(s)
      角谷寛
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] iRBDにみられる併存症状と、RBD診断のピットフォール2022

    • Author(s)
      角 幸頼, 角谷 寛, 尾関 祐二.
    • Organizer
      第41回日本認知症学会学術集会/第37回日本老年精神医学会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] 頭内爆発音に先行する特徴的な側頭部脳波活動 -電気生理学的アプローチ-2022

    • Author(s)
      角 幸頼, 今井 眞, 尾関 祐二, 角谷 寛.
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2022 Annual Research Report
    • Invited
  • [Presentation] CPAPからASVに変更し、夜間排尿の回数が減少した症例について2022

    • Author(s)
      角谷 寛
    • Organizer
      第13回睡眠呼吸フォーラム
    • Related Report
      2022 Annual Research Report
  • [Presentation] Relationships between Environmental Sound and Sleep Quality Based on Sleep Spindles.2022

    • Author(s)
      Saeda S, Fujiwara K, Sumi Y, Kadotani H.
    • Organizer
      AROB-ISBC-SWARM 2022, International Symposium on Artificial Life and Robotics
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] EEG-Based Anomaly Detection Model by One-Class Support Vector Machine for Dream Enactment Behavior in REM Sleep Behavior Disorder.2022

    • Author(s)
      Date S, Fujiwara K, Sumi Y, Kadotani H, Imai M, Ogawa K.
    • Organizer
      APSIPA ASC 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Which should be a beginning point for the disease duration of idiopathic rapid eye movement sleep behavior disorder, the estimated onset of symptoms, or the date when diagnosed?2022

    • Author(s)
      Sumi Y, Ubara A, Ozeki Y, Kadotani H.
    • Organizer
      Worldsleep2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 新型コロナウイルスによる、市職員のメンタルヘルスの変化: NinJa Sleep Study2022

    • Author(s)
      角谷 寛、大道 智恵, 角 幸頼,  乳原 彩香,  西川 公平、松田 有史,  尾関 祐二
    • Organizer
      第95回日本産業衛生学会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 市職員を対象とした自宅での1ch脳波測定における主観的・客観的な睡眠の評価の検討2022

    • Author(s)
      大道智恵, 角谷寛, 角幸頼, 乳原彩香, 西川公平, 松田有史, 尾関祐二.
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] レム睡眠行動障害におけるデルタ・ガンマ帯域パワー値の増大は夢内容行動化と関連する2022

    • Author(s)
      伊達俊坪, 藤原幸一, 角幸頼, 角谷寛, 今井眞, 小川景子.
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 孤発性(isolated)レム睡眠行動障害では罹病期間が短いほど抑うつ症状が強い: 系統的レビューとメタ解析.2022

    • Author(s)
      角 幸頼, 増田 史, 角谷 寛, 尾関 祐二.
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 小児のCPAPタイトレーションを要した一例2022

    • Author(s)
      相楽愛子、粟津和子、小西克彦、鯰江賢二、鐘ヶ江宏美、寺脇裕子、山田徳恵、松田有史、角幸頼、角谷寛.
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Development of EEG-based prediction model of dream enactment behavior in REM sleep behavior disorder,2022

    • Author(s)
      Shumpei Date, Koichi Fujiwara, Yukiyoshi Sumi, Hiroshi Kadotani, Makoto Imai, Keiko Ogawa.
    • Organizer
      44th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC'22)
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Prolonged sleep latency and reduced REM latency were associated with depression in a Japanese working population.2022

    • Author(s)
      Omichi C, Kadotani H, Sumi Y, Ubara A, Nishikawa K, Matsuda A, Ozeki Y.
    • Organizer
      26th Congress of the ESRS
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] レム睡眠行動障害におけるうつ病: 生物学的側面の理解と心理的サポートの必要性.2021

    • Author(s)
      角 幸頼, 尾関 祐二, 角谷 寛.
    • Organizer
      第62回日本神経学会学術大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 睡眠休養感と精神健康との関連2021

    • Author(s)
      鈴木正泰, 斎藤かおり, 吉池卓也, 金子宜之, 内海智博, 松井健太郎, 長尾賢太郎, 大槻怜, 有竹清夏, 角谷寛, 栗山健一.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 疫学研究におけるパルスオキシメーターの睡眠時無呼吸スクリーニングとしての診断精度2021

    • Author(s)
      角谷寛, 伊藤一樹, 上津昌広, 乳原彩香, 大道智恵, 松田有史, 宮本都和, 角幸頼, 松尾雅博.
    • Organizer
      第31回日本疫学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Relaxing Music Increases Sleep Spindles and Improve Sleep Quality2021

    • Author(s)
      Saeda S, Fujiwara K, Sumi Y, Kadotani H.
    • Organizer
      EMBC2021 (43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society)
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 睡眠外来患者における二質問票のうつ病判定精度に関する検討2021

    • Author(s)
      大道智恵, 角谷 寛, 宮本 都和, 乳原 彩香, 松田有史, 伊藤一樹, 角 幸頼, 森田 幸代,吉村 篤, 藤井 久彌子, 尾関 祐二
    • Organizer
      第34回日本総合病院精神医学会総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 日常の森林浴頻度と不眠症との関連:J-MICC Study大幸研究2021

    • Author(s)
      森田えみ、角谷寛、山田尚登、久保陽子、竹内研時、篠壁多恵、川合紗世、内藤真理子、若井建志.
    • Organizer
      第132回日本森林学会大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Self-isolation due to COVID-19 was not associated with changes in depression, sleepiness, and insomnia in Shiga prefecture, Japan2021

    • Author(s)
      Kadotani H, Ubara A, Sumi Y, Ito K, Matsuda A, Miyamoto T, Omichi C.
    • Organizer
      SLEEP2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 睡眠による休養感の欠如とうつ病発症リスクとの関連2021

    • Author(s)
      斎藤 かおり、吉池 卓也、大槻 怜、金子 宜之、内海 智博、長尾 賢太朗、松井 健太郎、有竹 清夏、角谷 寛、栗山 健一、鈴木 正泰
    • Organizer
      第117回日本精神神経学会学術総会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 畳み込みニューラルネットワークを用いた睡眠時無呼吸症候群スクリーニング.2021

    • Author(s)
      王歩雲、岩崎絢子、藤原幸一、永元哲治、角幸頼、加納学、井関邦敏、名嘉村博、角谷寛.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Per3 VNTR遺伝子多型と乳がん罹患歴との関連:J-MICC Study大幸研究.2021

    • Author(s)
      森田えみ、山田尚登、角谷寛、若井建志.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 滋賀医大の睡眠外来患者における新型コロナによる外出自粛と不眠、眠気、抑うつの関係.2021

    • Author(s)
      大道智恵, 乳原彩香, 角幸頼, 伊藤一樹, 松田有史, 宮本都和, 角谷寛.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 睡眠脳波に基づく日中の疲労と眠気の鑑別に関する調査.2021

    • Author(s)
      藤原幸一,後藤有貴,角幸頼,加納学,角谷寛.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] SST-RUSを用いた睡眠脳波解析による異なる音環境下でのスピンドル出現の評価.2021

    • Author(s)
      小枝正汰、藤原 幸一、木下貴文、角幸頼、角谷寛、山木清志、森島守人、川嶋隆宏.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] レム睡眠行動障害における軽症幻覚(minor hallucination)は神経変性疾患への進展のリスク因子2021

    • Author(s)
      角 幸頼, 乳原 彩香, 宮本 都和, 須藤 智志, 尾関 祐二, 角谷 寛.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 頭内爆発音に先行するカッパ律動の変動を認めた症例.2021

    • Author(s)
      宮本 都和, 角 幸頼, 須藤 智志, 角谷 寛, 尾関 祐二, 今井 眞.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 睡眠による休養感の欠如と高血圧発症との縦断的関連 ―既存コホートデータ(HCHS/SOL)による検討―.2021

    • Author(s)
      斎藤かおり, 吉池卓也, 金子宜之, 大槻 怜, 内海智博, 長尾賢太朗, 松井健太郎, 有竹清夏, 角谷 寛, 栗山健一 , 鈴木正泰.
    • Organizer
      日本睡眠学会第46回定期学術集会
    • Related Report
      2021 Annual Research Report
  • [Book] 睡眠呼吸障害Update20222022

    • Author(s)
      角谷寛. 他
    • Total Pages
      256
    • Publisher
      ライフ・サイエンス社
    • ISBN
      4898017428
    • Related Report
      2022 Annual Research Report
  • [Book] 講座精神疾患の臨床 6 てんかん 睡眠・覚醒障害2022

    • Author(s)
      松田有史, 角谷寛. 他
    • Total Pages
      448
    • Publisher
      中山書店
    • ISBN
      9784521748269
    • Related Report
      2022 Annual Research Report
  • [Book] 快眠研究と製品開発、社会実装  ~生体計測から睡眠教育、スリープテック、ウェルネス、地域創生まで~2022

    • Author(s)
      大道智恵、角谷寛. 他
    • Total Pages
      812
    • Publisher
      エヌ・ティー・エス
    • ISBN
      9784860437848
    • Related Report
      2022 Annual Research Report

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Published: 2021-04-28   Modified: 2024-12-25  

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