Elucidation of the thalamocortical network that enables strategic updates of perceptual and experience representations

• Project/Area Number: 23K24000
• Project/Area Number (Other): 22H02737 (2022-2023)
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Multi-year Fund (2024); Single-year Grants (2022-2023)
• Section: 一般
• Review Section: Basic Section 46030:Function of nervous system-related
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: Schmitt Lukas 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー (10871329)
• Project Period (FY): 2022-04-01 – 2025-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000); Fiscal Year 2024: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2023: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000); Fiscal Year 2022: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
• Keywords: Perception / Inference / Thalamocortical / Cognition / Adaptability / Thalamus / Cortex / Thalamocortical Networks / TRN / Inhibition / Updating

Outline of Research at the Start

Effective behavior requires that we both perceive the world and predict future events. To do this, the brain creates an "internal model" by selectively integrating current and past experiences. In this study, we use advanced techniques to understand how the internal model is created and updated.