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A cluster randomized controlled trial to evaluate pharmacy-based health promotion program to improve blood pressure control in Bangladesh, India and Pakistan

Research Project

Project/Area Number 23K24566
Project/Area Number (Other) 22H03308 (2022-2023)
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeMulti-year Fund (2024)
Single-year Grants (2022-2023)
Section一般
Review Section Basic Section 58010:Medical management and medical sociology-related
Research InstitutionHitotsubashi University

Principal Investigator

RAHMAN Mizanur  一橋大学, 社会科学高等研究院, 准教授 (10726433)

Co-Investigator(Kenkyū-buntansha) 中村 良太  一橋大学, 社会科学高等研究院, HIAS客員研究員 (00717209)
佐藤 主光  一橋大学, 社会科学高等研究院, 教授 (50313458)
ALAM MD・ASHRAFUL  東京大学, 医学部附属病院, 特任研究員 (80866632)
Project Period (FY) 2024-04-01 – 2025-03-31
Project Status Completed (Fiscal Year 2024)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2024: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2023: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2022: ¥8,970,000 (Direct Cost: ¥6,900,000、Indirect Cost: ¥2,070,000)
KeywordsBlood pressure / Quality of life / Pharmacy / Bangladesh / Pakistan / Quality of life Pharmacy / Hypertension control / Community pharmacy / Cost-effectiveness / India / Health promotion / Treatment adherence / Cluster RCT / blood pressure / quality of life / pharmacy / hypertension
Outline of Research at the Start

Our study evaluates the impact of pharmacy-based health promotion on hypertensive patients in resource-limited areas by using a cluster-randomized trial. There are 3,600 hypertensive adults in Bangladesh and 360 in Pakistan participating. Phases include baseline surveys with interventions, midline surveys with interventions and follow-ups, and endline surveys with impact evaluations. Two intervention groups will provide community pharmacies with educational training, counseling, phone calls, and text messages. Blood pressure, quality of life, and cost-effectiveness will also be measured.

Outline of Final Research Achievements

Our research showed that community pharmacists can effectively help people manage high blood pressure. In Bangladesh, we recruited 3,600 participants with a response rate of approximately 96%. Participants who received education and counseling from pharmacists had significantly better control of their blood pressure, with about 65% achieving ideal blood pressure levels compared to 48% who did not receive pharmacist support. These participants also saw notable health improvements, such as an average weight loss of 1.5 kg and enhanced overall well-being. In Pakistan, we initially recruited 360 participants, with 320 participants remaining at the final follow-up; data collection is complete and the final analysis is currently underway, with early results indicating similar benefits. These findings indicate that pharmacies could be a valuable resource for improving public health, particularly in communities with limited access to traditional healthcare services.

Academic Significance and Societal Importance of the Research Achievements

本研究は、地域薬局が非感染性疾患(NCDs)の主要な危険因子である高血圧の管理を効果的に支援することを実証しました。バングラデシュとパキスタンでは、薬剤師の指導が血圧管理と健康状態全般を有意に改善し、特に医療資源の限られたコミュニティにおいてNCDリスクを低減する実現可能な方法を提供しました。

Report

(4 results)
  • 2024 Annual Research Report   Final Research Report ( PDF )
  • 2023 Annual Research Report
  • 2022 Annual Research Report
  • Research Products

    (4 results)

All 2025 2024

All Journal Article (3 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (1 results) (of which Invited: 1 results)

  • [Journal Article] Healthy lifestyle knowledge and age at hypertension diagnosis: a primary health care based survey in Bangladesh2025

    • Author(s)
      Islam Md Monirul、Hossain Md. Safayet、Rahman Md. Mizanur、Nakamura Ryota、Sato Motohiro
    • Journal Title

      Journal of Human Hypertension

      Volume: NA Issue: 6 Pages: 1-9

    • DOI

      10.1038/s41371-025-01019-3

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Socio-demographic disparities in health-related quality of life in hypertensive patients in Bangladesh: a comprehensive survey analysis2025

    • Author(s)
      Rahman Md. Mizanur、Sorkar Md. Nesar Uddin、Nakamura Ryota、Islam Md. Monirul、Alam Md. Ashraful、Azmat Syed Khurram、Sato Motohiro
    • Journal Title

      Quality of Life Research

      Volume: - Issue: 5 Pages: 1-13

    • DOI

      10.1007/s11136-025-03912-3

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effectiveness of a Community Pharmacy-Based Health Promotion Program on Hypertension in Bangladesh and Pakistan: Study Protocol for a Cluster-Randomized Controlled Trial2024

    • Author(s)
      Rahman Md. Mizanur、Nakamura Ryota、Islam Md. Monirul、Alam Md. Ashraful、Azmat Syed Khurram、Sato Motohiro
    • Journal Title

      Healthcare

      Volume: 12 Issue: 14 Pages: 1402-1402

    • DOI

      10.3390/healthcare12141402

    • Related Report
      2024 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Hypertension Control Through Community Pharmacy Intervention in Rural Bangladesh: Results from a Cluster RCT2025

    • Author(s)
      Md. Mizanur Rahman
    • Organizer
      The 75th Regular Seminar
    • Related Report
      2024 Annual Research Report
    • Invited

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Published: 2022-04-19   Modified: 2026-01-16  

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