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Understanding activation mechanism and evolution of paired NLR immune receptors by paralog suppression and neo-functionalization

Research Project

Project/Area Number 23K26906
Project/Area Number (Other) 23H02213 (2023)
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeMulti-year Fund (2024)
Single-year Grants (2023)
Section一般
Review Section Basic Section 39040:Plant protection science-related
Research InstitutionOkayama University

Principal Investigator

河野 洋治  岡山大学, 資源植物科学研究所, 教授 (00406175)

Co-Investigator(Kenkyū-buntansha) 深田 史美  岡山大学, 資源植物科学研究所, 特任助教 (80740414)
Project Period (FY) 2023-04-01 – 2027-03-31
Project Status Granted (Fiscal Year 2024)
Budget Amount *help
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2026: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2025: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2024: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2023: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
KeywordsNLR免疫受容体 / イネ / 免疫
Outline of Research at the Start

Pit1とPit2をモデルケースとして、ペアNLRタンパク質の拮抗するメカニズムやリガンドである病原菌のエフェクターを認識する機構、ペアNLRタンパク質とエフェクターが攻撃と防御に関連する形質で共進化する過程も解明できる独自性の高い研究を展開する。

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Published: 2023-04-18   Modified: 2024-08-08  

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