Novel iron metabolism started from transferin antibody

• Project/Area Number: 23K27631
• Project/Area Number (Other): 23H02940 (2023)
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Multi-year Fund (2024); Single-year Grants (2023)
• Section: 一般
• Review Section: Basic Section 54010:Hematology and medical oncology-related
• Research Institution: Osaka University (2024); Tokai University (2023)
• Principal Investigator: 幸谷 愛 大阪大学, 微生物病研究所, 教授 (00517477)
• Project Period (FY): 2023-04-01 – 2028-03-31
• Project Status: Granted (Fiscal Year 2024)
• Budget Amount: ¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000); Fiscal Year 2027: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2026: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000); Fiscal Year 2025: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2024: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2023: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
• Keywords: 劇症型NK白血病 / 鉄代謝 / トランスフェリン受容体

Outline of Research at the Start

鉄欠乏が引き起こすG0G1アレストが、抗トランスフェリン抗体を投与した際のANKL
細胞に全く認められないことについて、その詳細を明らかにする。