| Project/Area Number |
23KF0128
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| Research Category |
Grant-in-Aid for JSPS Fellows
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| Allocation Type | Multi-year Fund |
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| Section | 外国 |
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| Review Section |
Basic Section 42020:Veterinary medical science-related
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| Research Institution | Hokkaido University |
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Principal Investigator |
中尾 亮 北海道大学, 獣医学研究院, 准教授 (50633955)
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| Co-Investigator(Kenkyū-buntansha) |
TEO ERNEST 北海道大学, 獣医学研究院, 外国人特別研究員
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| Project Period (FY) |
2023-09-27 – 2026-03-31
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| Project Status |
Granted (Fiscal Year 2023)
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| Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2025: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2024: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2023: ¥500,000 (Direct Cost: ¥500,000)
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| Keywords | Ticks / Abundance / Geographic distribution / Distribution models / Climate change / Invasive species / Phylogeography |
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| Outline of Research at the Start |
マダニは人や動物に寄生して吸血し、病原体を媒介することがある。どの地域にどの種類のマダニが生息しているかは、過去の調査研究によって調べられてきた。しかしながら、人間活動や気候変動などによって、マダニの生息域が近年変化してきている。本研究では、将来の気候予測データと、マダニの遺伝子情報を解析することで、将来どのような場所にマダニが生息し、マダニが媒介する感染症のリスクが高まるかを明らかにすることを目的とする。
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| Outline of Annual Research Achievements |
Ticks are a big concern to the health of humans and to animals because they transmit a great variety of disease-causing pathogens. For my fellowship, I planned to model the potential geographic range of select ticks, while considering genetics. To that end, since the start of my fellowship, I focused on the tick, Dermacentor auratus. D. auratus is a tick that occurs in the greater part of South and Southeast Asia, and many disease-causing bacteria and viruses have been detected in this tick, including Rickettsia, Borrelia, Kyasanaur forest disease virus and African swine fever virus. Using a species distribution model, I projected the potential geographic range of D. auratus, which will help inform the surveillance of D. auratus and its associated pathogens in South and Southeast Asia.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
Although I have only completed one of the many projects that I had planned in the first six months of my fellowship, I am continuously collecting and curating data for at least five other projects which I am working on. Once data collection and data curation for each project is complete, analyses of the curated data will likely be quick, and I foresee that my progress will move on as planned. For these five other projects, I estimate data collection and curation to be about 100%, 90%, 90%, 70%, and 30% for the five projects, in chronological order of the targeted deadlines that I have set for manuscript submissions. Also, I have worked out and tested the materials and methods required for my laboratory experiments, and will start on these experiments soon.
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| Strategy for Future Research Activity |
I will model the potential geographic range of a few species of ticks of medical and veterinary importance. Noting that some of these species have distinct populations which may transmit different pathogens, I will study, in the laboratory, whether different populations of a single species have different climatic tolerances and climatic profiles. Informed by these data, I will model the potential phylogeographic range of these populations in relation to climate.
I will also study tick-host and tick-pathogen associations and prioritize ticks that are likely to be invasive in Asia Pacific. Simultaneously, I will try to figure out what has allowed certain species of ticks to be invasive and what has prevented other species of ticks to be unable to spread beyond their current geographic range.
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