Project/Area Number |
23KF0197
|
Research Category |
Grant-in-Aid for JSPS Fellows
|
Allocation Type | Multi-year Fund |
Section | 外国 |
Review Section |
Basic Section 37030:Chemical biology-related
|
Research Institution | The University of Tokyo |
Principal Investigator |
菅 裕明 東京大学, 大学院理学系研究科(理学部), 教授 (00361668)
|
Co-Investigator(Kenkyū-buntansha) |
PHILIPPE GREGOIRE 東京大学, 大学院理学系研究科(理学部), 外国人特別研究員
|
Project Period (FY) |
2023-11-15 – 2026-03-31
|
Project Status |
Granted (Fiscal Year 2023)
|
Budget Amount *help |
¥2,000,000 (Direct Cost: ¥2,000,000)
Fiscal Year 2025: ¥500,000 (Direct Cost: ¥500,000)
Fiscal Year 2024: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2023: ¥500,000 (Direct Cost: ¥500,000)
|
Outline of Research at the Start |
The aim of this project is to develop a new type of molecule that relies on ubiquitin grafting to selectively degrade targeted proteins. 1) Proof of concept using a well characterized protein 2) Application to other targets and cell delivery 3) Publication/ patent & blood-brain barrier targeting
|