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Elucidation of neural mechanisms of primate cognitive memory using an integrated approach of magnetic resonance imaging and optogenetic manipulation

Research Project

Project/Area Number 24220008
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Neuroscience in general
Research InstitutionThe University of Tokyo

Principal Investigator

MIYASHITA Yasushi  東京大学, 大学院医学系研究科(医学部), 名誉教授 (40114673)

Co-Investigator(Kenkyū-buntansha) 饗場 篤  東京大学, 医学(系)研究科(研究院), 教授 (20271116)
内山 安男  順天堂大学, 医学部, 特任教授 (10049091)
Project Period (FY) 2012-05-31 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥217,490,000 (Direct Cost: ¥167,300,000、Indirect Cost: ¥50,190,000)
Fiscal Year 2016: ¥54,210,000 (Direct Cost: ¥41,700,000、Indirect Cost: ¥12,510,000)
Fiscal Year 2015: ¥54,600,000 (Direct Cost: ¥42,000,000、Indirect Cost: ¥12,600,000)
Fiscal Year 2014: ¥32,760,000 (Direct Cost: ¥25,200,000、Indirect Cost: ¥7,560,000)
Fiscal Year 2013: ¥32,760,000 (Direct Cost: ¥25,200,000、Indirect Cost: ¥7,560,000)
Fiscal Year 2012: ¥43,160,000 (Direct Cost: ¥33,200,000、Indirect Cost: ¥9,960,000)
Keywords認知神経科学 / 磁気共鳴機能画像法(fMRI) / 霊長類 / 大脳 / 光遺伝学 / 磁気共鳴機能画像法 / 光遺伝子 / 大域的大脳ネットワーク / 記憶システム / 磁気共鳴画像法
Outline of Final Research Achievements

I analyzed the neural mechanisms underlying cognitive memory from two view-points: 1) First, we investigated how the whole-brain neural network operates through the exchange of specific information that originates from local microcircuits and single neurons. Particularly, we compared microcircuit operations across areas in the monkey temporal cortex and found a novel principle for cortical computation on object processing, in which precursor codes for object features are constructed in a lower-order area before prevalence in a higher-order area. 2) Second, we investigated causal impacts of reversible silencing of the cortical sites that such a whole-brain network search has successfully identified. Particularly, we discovered a center of metamemory for temporally remote events in the prefrontal area 9. These studies provided an outstanding development in understanding of causal neural origin of high-level cognition such as metamemory.

Assessment Rating
Verification Result (Rating)

A+

Assessment Rating
Result (Rating)

A+: Progress in the research exceeds the initial goal. More than expected research results are expected.

Report

(9 results)
  • 2017 Research Progress Assessment (Verification Result) ( PDF )
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report   Abstract(Research Progress Assessment) ( PDF )   Research Progress Assessment (Result) ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (69 results)

All 2017 2016 2015 2014 2013 2012 Other

All Journal Article (30 results) (of which Peer Reviewed: 30 results,  Acknowledgement Compliant: 11 results,  Open Access: 12 results) Presentation (36 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results) Remarks (3 results)

  • [Journal Article] Causal neural network of metamemory for retrospection in primates2017

    • Author(s)
      Miyamoto, K., Osada, T., Setsuie, R., Takeda, M., Tamura, K., Adachi, Y., and Miyashita, Y.
    • Journal Title

      Science

      Volume: 355 Issue: 6321 Pages: 188-193

    • DOI

      10.1126/science.aal0162

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Laminar module cascade from layer 5 to 6 implementing cue-to-target conversion for object memory retrieval in the primate temporal cortex2016

    • Author(s)
      Koyano, K., Takeda, M., Matsui, T., Hirabayashi, T., Ohashi, Y., Miyashita, Y.
    • Journal Title

      Neuron

      Volume: 92 Issue: 2 Pages: 518-529

    • DOI

      10.1016/j.neuron.2016.09.024

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] op-down regulation of laminar circuit via inter-area signal for successful object memory recall in monkey temporal cortex.2015

    • Author(s)
      Takeda, M., Koyano, W.K., Hirabayashi, T., Adachi, Y. and Miyashita,Y.
    • Journal Title

      Neuron

      Volume: 印刷中 Issue: 3 Pages: 840-852

    • DOI

      10.1016/j.neuron.2015.03.047

    • Related Report
      2015 Annual Research Report 2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Dynamically allocated hub in task-evoked network predicts the vulnerable prefrontal locus for contextual memory retrieval in macaques.2015

    • Author(s)
      Osada,T., Adachi,Y., Miyamoto,K., Jimura, K.,Setsuie,R.and Miyashita, Y
    • Journal Title

      PLoS Biol.

      Volume: 13(6)

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Avian sarcoma leukosis virus receptor-envelope system for simultaneous dissection of multiple neural circuits in mammalian brain.2015

    • Author(s)
      Matsuyama, M., Ohashi, Y., Tsubota, T., Yaguchi, M., Kato, S., Kobayashi, K. and Miyashita, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A.

      Volume: 112 Issue: 22 Pages: 2947-2956

    • DOI

      10.1073/pnas.1423963112

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Dynamically allocated hub in task-evoked network predicts the vulnerable.2015

    • Author(s)
      Osada,T., Adachi,Y., Miyamoto,K., Jimura, K.,Setsuie,R.and Miyashita, Y
    • Journal Title

      PLoS Biol.

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effects of rTMS of pre-supplementary motor area on fronto basal ganglia network activity during stop-signal task2015

    • Author(s)
      Watanabe, T., Hanajima, R., Shirota, Y., Tsutsumi, R., Shimizu, T., Hayashi, T., Terao, Y., Ugawa, Y., Katsura, M., Kunimatsu, A., Ohtomo, K., Hirose, S., Miyashita, Y. and Konishi, S.
    • Journal Title

      J. Neurosci.

      Volume: 35 Issue: 12 Pages: 4813

    • DOI

      10.1523/jneurosci.3761-14.2015

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cofilin1 Controls Transcolumnar Plasticity in Dendritic Spines in Adult Barrel Cortex2015

    • Author(s)
      Tadashi Tsubota, Reiko Okubo-Suzuki, Yohei Ohashi, Keita Tamura, Koshin Ogata, Masae Yaguchi, Makoto Matsuyama, Kaoru Inokuchi, Yasushi Miyashita
    • Journal Title

      PLOS Biology

      Volume: 13(2) Issue: 2 Pages: e1002070-e1002070

    • DOI

      10.1371/journal.pbio.1002070

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Computational principles of microcircuits for visual object processing in the macaque temporal cortex.2014

    • Author(s)
      Hirabayashi, T. and Miyashita, Y.
    • Journal Title

      Trends in Neurosci.

      Volume: 37 Issue: 3 Pages: 178-187

    • DOI

      10.1016/j.tins.2014.01.002

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Two distinct neural mechanisms underlying indirect reciprocity2014

    • Author(s)
      Watanabe T, Takezawa M, Nakawake Y, Kunimatsu A, Yamasue H, Nakamura M, et al
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America

      Volume: 111(11) Issue: 11 Pages: 3990-3995

    • DOI

      10.1073/pnas.1318570111

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Distinct neuronal interactions in anterior inferotemporal areas of macaque monkeys during retrieval of object association memory.2014

    • Author(s)
      Hirabayashi, T., Tamura, K., Takeuchi, D., Takeda, M., Koyano, W.K., and Miyashita, Y.
    • Journal Title

      J. Neurosci.

      Volume: 34 Issue: 28 Pages: 9377-9388

    • DOI

      10.1523/jneurosci.0600-14.2014

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Dissociable memory traces within the macaque medial temporal lobe predict subsequent recognition performance.2014

    • Author(s)
      Miyamoto, K., Adachi, Y., Osada, T., Watanabe, T., Kimura, HM., Setsuie, R., Miyashita, Y.
    • Journal Title

      The Journal of Neuroscience

      Volume: 34 Issue: 5 Pages: 1988-1997

    • DOI

      10.1523/jneurosci.4048-13.2014

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Network-dependent modulation of brain activity during sleep.2014

    • Author(s)
      Watanabe T, Kan S, Koike T, Misaki M, Konishi S, Miyauchi S, Miyashita Y, and Masuda N.
    • Journal Title

      NeuroImage

      Volume: 98 Pages: 1-10

    • DOI

      10.1016/j.neuroimage.2014.04.079

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Bidirectional effects on inter-hemispheric resting-state functional connectivity induced by excitatory and inhibitory repetitive transcranial magnetic stimulation.2013

    • Author(s)
      Watanabe T, Abe O, Kuwabara H, Yahata N, Takano Y, Iwashiro N, Natsubori T, Aoki Y, Takao H, Kawakubo Y, Kamio Y, Kato N, Miyashita Y, Kasai K, and Yamasue H.
    • Journal Title

      Human Brain Mapping

      Volume: 35 Issue: 5 Pages: 1896-1905

    • DOI

      10.1002/hbm.22300

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Microcircuits for hierarchical elaboration of object coding across primate temporal areas.2013

    • Author(s)
      Hirabayashi T, Takeuchi D, Tamura K, Miyashita Y.
    • Journal Title

      Science

      Volume: 341 Issue: 6142 Pages: 191-195

    • DOI

      10.1126/science.1236927

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Characterization of the properties of seven promoters in the motor cortex of rats and monkeys after lentiviral vector-mediated gene2013

    • Author(s)
      Yaguchi M., et al.
    • Journal Title

      Human Gene Therapy Methods

      Volume: 24 Issue: 6 Pages: 333-344

    • DOI

      10.1089/hgtb.2012.238

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Functional relevance of micromodules in the human association cortex delineated with high- resolution fMRI2013

    • Author(s)
      Hirose S., Watanabe T., Wada H., Imai Y., Machida T., Shirouzu I., Miyashita Y., Konishi S
    • Journal Title

      Cerebral Cortex

      Volume: 23 Issue: 12 Pages: 2863-2871

    • DOI

      10.1093/cercor/bhs268

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Functional differentiation of memory retrieval network in macaque posterior parietal cortex2013

    • Author(s)
      Miyamoto, K., Osada, T., Adachi, Y., Matsui, T., Kimura, HM. Miyashita
    • Journal Title

      Neuron

      Volume: 77 Issue: 4 Pages: 787-799

    • DOI

      10.1016/j.neuron.2012.12.019

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional micro-circuit recruited during retrieval of object association memory in monkey perirhinal cortex.2013

    • Author(s)
      Hirabayashi, T., Takeuchi, D. and Tamura, K. and Miyashita, Y.
    • Journal Title

      Neuron

      Volume: 77 Issue: 1 Pages: 192-203

    • DOI

      10.1016/j.neuron.2012.10.031

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional Connectivity between Anatomically Unconnected Areas is Shaped by Collective Network-Level Effects in the Macaque Cortex2012

    • Author(s)
      Adachi Y, Osada T, Spoms O, Watanabe T, Matsui T, Miyamoto K, Miyashita Y
    • Journal Title

      Cerebral Cortex

      Volume: (掲載決定)(印刷中) Issue: 7 Pages: 1586-1592

    • DOI

      10.1093/cercor/bhr234

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Optogenetic manipulation of Purkinje cell activity in vivo2012

    • Author(s)
      Tsubota T., et al
    • Journal Title

      Neuroscience

      Volume: (In Press)(印刷中)(掲載確定) Pages: 137-144

    • DOI

      10.1016/j.neuroscience.2012.03.014

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Functional dissociation between anterior and posterior temporal cortical regions during retrieval of remote memory2012

    • Author(s)
      Watanabe T., Kimura H. M., Hirose S., Wada H., Imai Y., Machida T., Shirouzu I., Miyashita Y., Konishi S
    • Journal Title

      Journal of Neuroscience

      Volume: 32 Issue: 28 Pages: 9659-9670

    • DOI

      10.1523/jneurosci.5553-11.2012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Local signal time-series during rest used for areal boundary mapping in individual human brains2012

    • Author(s)
      Hirose S., Watanabe T., Jimura K., Katsura M., Kunimatsu A., Abe O., Ohtomo K., Miyashita Y., Konishi S
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 5 Pages: e36496-e36496

    • DOI

      10.1371/journal.pone.0036496

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficiency of go/no-go task performance implemented in the left hemisphere2012

    • Author(s)
      Hirose S., Chikazoe J., Watanabe T., Jimura K., Kunimatsu A., Abe O., Ohtomo K., Miyashita Y., Konishi S
    • Journal Title

      Journal of Neuroscience

      Volume: 32 Issue: 26 Pages: 9059-9065

    • DOI

      10.1523/jneurosci.0540-12.2012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neurodynamics of Cognitive Set Shifting in Monkey Frontal Cortex and Its Causal Impact on Behavioral Flexibility.2012

    • Author(s)
      Kamigaki, T., Fukushima, T., Tamura, K. and Miyashita, Y.
    • Journal Title

      J. Cogn. Neurosci.

      Volume: 24 Issue: 11 Pages: 2171-2185

    • DOI

      10.1162/jocn_a_00277

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diminished Medial Prefrontal Activity Behind Autistic Social Judgments of Incongruent Information.2012

    • Author(s)
      渡部喬光
    • Journal Title

      PLoS One

      Volume: 7 Issue: 6 Pages: e39561-e39561

    • DOI

      10.1371/journal.pone.0039561

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] To bet, or not to bet : that is the question of SEF spikes2012

    • Author(s)
      Miyamoto, K., Hirabayashi, T., Miyashita, Y.
    • Journal Title

      Neuron

      Volume: 75 Issue: 3 Pages: 358-360

    • DOI

      10.1016/j.neuron.2012.07.012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A glass-coated tungsten microelectrode enclosing optical fibers for optogenetic exploration in primate deep brain structures2012

    • Author(s)
      Tamura K., et al.
    • Journal Title

      Journal of Neuroscience Methods

      Volume: Vol.211, Issue 1 Issue: 1 Pages: 49-57

    • DOI

      10.1016/j.jneumeth.2012.08.004

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] fMRI activity in the macaque cerebellum evoked by intracortical microstimulation of the primary somatosensory cortex : evidence for polysynaptic propagation2012

    • Author(s)
      Matsui, T, Koyano, KW, Tamura, K, Osada, T, Adachi, Y, Miyamoto, K, Chikazoe, J, Kamigaki, K, Miyashita, Y
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 10 Pages: e47515-e47515

    • DOI

      10.1371/journal.pone.0047515

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] FoxP2 is a parvocellular-specific transcription factor in the visual thalamus of monkeys and ferrets.2012

    • Author(s)
      Iwai L., Ohashi Y. van der List D., Usrey W. M., Miyashita Y., Kawasaki H.
    • Journal Title

      Cerebral Cortex

      Volume: - Issue: 9 Pages: 2204-2212

    • DOI

      10.1093/cercor/bhs207

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Efficient ArchT-mediated optogenetic inhibition by red-shifted off-peak 594-nm light in vivo.2016

    • Author(s)
      Setsuie, R., Tamura, K., Takeda, M., Miyamoto, K. and Miyashita, Y.
    • Organizer
      SfN's 46th annual meeting
    • Place of Presentation
      サンディエゴ(米国)
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Hierarchical prefrontal network arising from frontal pole area 10 during contextual memory retrieval.2016

    • Author(s)
      Osada,T., Adachi, Y., Miyamoto, K., Jimura, K., Setsuie, R., Watanabe, T. and Miyashita, Y.
    • Organizer
      第39回日本神経科学大会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Inter-area signal targeting translaminar processing during successful memory retrieval in macaque temporal cortex.2015

    • Author(s)
      Takeda, M., Koyano, W.K., Hirabayashi, T., Adachi, Y., Ishii, T., Miyashita, Y.
    • Organizer
      SfN 45th annual meeting
    • Place of Presentation
      McCormick Place in Chicago, U.S.A.
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Hub-centric prefrontal network predicts lesion-effective site for contextual memory in macaques.2015

    • Author(s)
      Osada, T., Adachi, Y., Miyamoto, K., Jimura, K., Setsuie, R., Watanabe, T. Miyashita, Y
    • Organizer
      SfN 45th annual meeting
    • Place of Presentation
      McCormick Place in Chicago, U.S.A.
    • Year and Date
      2015-10-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cognitive memory in the primate cortex: global network and local circuit.2014

    • Author(s)
      Miyashita, Y.
    • Organizer
      International Symposium 2014 ‘Vision, Memory, Thought : how cognition emerges from neural network’
    • Place of Presentation
      Ito International Research Center, The University of Tokyo(東京都文京区)
    • Year and Date
      2014-12-06 – 2014-12-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Microcircuits for hierarchical coding of object-object association across inferotemporal areas of macaques.2014

    • Author(s)
      Hirabayashi, T., Tamura, K., Takeuchi, D., Takeda, M., Koyano, K. W. and Miyashita, Y.
    • Organizer
      The Society for Neuroscience 44rd Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dissociable memory formation processes within the macaque medial temporal lobe.2014

    • Author(s)
      Miyamoto, K., Adachi Y., Osada, T., Watanabe, T., Setsuie, R., Kimura, M.H., Watanabe, T. and Miyashita, Y.
    • Organizer
      The Society for Neuroscience 44rd Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dissecting multiple neuronal pathways in mammalian brain using Avian sarcoma and leukosis virus envelope-receptor pairs.2014

    • Author(s)
      Matsuyama, M., Ohashi, Y., Tsubota, T., Yaguchi, M., Mamada, K., Kato, S., Kobayashi, K. and Miyashita, Y.
    • Organizer
      The Society for Neuroscience 44rd Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Distribution of neurons responsible for visual stimulus-stimulus association memory in the macaque perirhinal cortex area 36.2014

    • Author(s)
      Koyano, W.K., Takeda, M., Matsui, T., Ohashi, Y., Hirabayashi, T., Kakizawa, K., Watanabe, T. and Miyashita, Y.
    • Organizer
      The Society for Neuroscience 44rd Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Fronto-temporal mechanisms involved in rapid formation of pair-association memory.2014

    • Author(s)
      Jimura, K., Hirose, S., Wada, H., Yoshizawa, Y., Imai, Y., Akahane, M., Machida, T. Shirouzu, I., Koike, Y., Miyashita, Y. and Konishi S.
    • Organizer
      The Society for Neuroscience 44rd Annual Meeting
    • Place of Presentation
      Walter E. Washington Convention Center(USA)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] Three orthogonal Gate-Tag vectors for pathway-specific gene trasfer in the mammalian brain.2014

    • Author(s)
      Matsuyama, M., Ohashi,Y., Tsubota,T., Yaguchi,M., Mamada,K., Kato,S.,
    • Organizer
      The 37th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] Dissociable activity patterns in the macaque medial temporal lobe during memory encoding predict subsequent recognition performance.2014

    • Author(s)
      Miyamoto, K., Adachi,Y., Osada,T., Watanabe,T., Kimura,M.H., Setsuie,R.,Watanabe, F.T. and Miyashita, Y.
    • Organizer
      The 37th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Related Report
      2014 Annual Research Report
  • [Presentation] Short-term changes in behavioral efficiency and brain activity associated with response inhibition.2014

    • Author(s)
      Hirose S, Jimura K, Kunimatsu A, Abe O, Ohtomo K,Miyashita Y and Konishi S
    • Organizer
      The 91st Annual Meeting of the Physiology Society of Japan
    • Place of Presentation
      Kagoshima University, Korimoto Campus(鹿児島市)
    • Year and Date
      2014-03-16 – 2014-03-18
    • Related Report
      2013 Annual Research Report
  • [Presentation] Directional signal flow between different classes of memory neurons during retrieval of object association memory in macaque inferior temporal cortex.2013

    • Author(s)
      Hirabayashi T, Takeuchi D, Tamura K, Takeda M, Koyano KW and Miyashita Y
    • Organizer
      The Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(USA)
    • Year and Date
      2013-11-09 – 2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] MRI-assisted single-unit recording revealed precise neuronal map in the perirhinal cortices of macaque monkeys performing a visual–association task.2013

    • Author(s)
      Koyano WK, Takeda M, Matsui T, Ohashi Y, Hirabayashi T, Kakizawa K, Watanabe T and Miyashita Y
    • Organizer
      The Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(USA)
    • Year and Date
      2013-11-09 – 2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] Neural correlates of primacy and recency effects in macaque memory retrieval network.2013

    • Author(s)
      Miyamoto K, Osada T, Adachi Y, Mastui T, Kimura MH, Watanabe T, Setsuie R and Miyashita Y
    • Organizer
      The Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(USA)
    • Year and Date
      2013-11-09 – 2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] Across-areal signal flow between area 36 and TE of macaques performing the pair-association task.2013

    • Author(s)
      Takeda M, Koyano WK, Hirabayashi T, Ishi T, Watanabe T and Miyashita Y
    • Organizer
      The Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(USA)
    • Year and Date
      2013-11-09 – 2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] EGFP expressions in the cerebral cortex of rats and monkeys under control of various promoters after lentiviral transduction.2013

    • Author(s)
      Yaguchi M, Ohashi Y, Tsubota T, Sato A, Koyano WK, Wang N, Matsuyama M, Sekine T and Miyashita Y
    • Organizer
      The Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(USA)
    • Year and Date
      2013-11-09 – 2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] Hierarchal neural network underlying resolution of incongruent nonverbal and verbal social information.2013

    • Author(s)
      Watanabe T, Yahata N, Kawakubo Y, Inoue H, Takano Y, Iwashiro N, Natsubori T, Takao H, Sasaki H, Gonoi W, Murakami M, Katsura M, Kunimatsu A, Abe O, Kasai K Miyashita Y and Yamasue H
    • Organizer
      The Society for Neuroscience 43rd Annual Meeting
    • Place of Presentation
      San Diego Convention Center(USA)
    • Year and Date
      2013-11-09 – 2013-11-13
    • Related Report
      2013 Annual Research Report
  • [Presentation] Lentivirus-mediated RNAi for local knockdown of NMDAR1 in adult rat barrel cortex.2013

    • Author(s)
      Tsubota T, Ohashi Y, Tamura K, Yaguchi M, Matsuyama M, Sekine T and Miyashita Y
    • Organizer
      The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference center(京都市)
    • Year and Date
      2013-06-20 – 2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] Modular structures within macaque memory retrieval network implement functional differentiation during serial probe recognition task.2013

    • Author(s)
      Miyamoto K, Osada T, Adachi Y, Matsui T, Kimura HM, Watanabe T Setsuie R and Miyashita Y
    • Organizer
      The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference center(京都市)
    • Year and Date
      2013-06-20 – 2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] Inter-regional task-related functional correlation in temporo-parietal networks: A functional MRI study of recency judgments.2013

    • Author(s)
      Hirose S, Kimura HM, Kunimatsu A, Abe O, Ohtomo K, Miyashita Y and Konishi S
    • Organizer
      The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference center(京都市)
    • Year and Date
      2013-06-20 – 2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] cross-areal analysis of mnemonic backward signal flow between area 36 and TE of macaques.2013

    • Author(s)
      Takeda M, Koyano KW and Miyashita Y
    • Organizer
      The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference center(京都市)
    • Year and Date
      2013-06-20 – 2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] Simplicity of human brain networks: resting-state functional brain networks can be accurately described by a pairwise maximum entropy model.2013

    • Author(s)
      Watanabe T, Hirose S, Wada H, Imai Y, Machida T, Shirouzu I, Konishi S, Miyashita Y and Masuda T
    • Organizer
      The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference center(京都市)
    • Year and Date
      2013-06-20 – 2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] Comparison of seven promoters in the rat and monkey cerebral cortices using lentiviral vectors.2013

    • Author(s)
      Yaguchi M, Ohashi Y, Tsubota T, Sato A, Koyano WK, Wang N, Matsuyama M, Sekine T and Miyashita Y
    • Organizer
      The 36th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Kyoto International Conference center(京都市)
    • Year and Date
      2013-06-20 – 2013-06-22
    • Related Report
      2013 Annual Research Report
  • [Presentation] Differences in Anatomical Basis of Local vs Global Resting State Networks.2013

    • Author(s)
      Adachi Y and Miyashita Y
    • Organizer
      The 19th Annual Meeting of the Organization for Human Brain Mapping
    • Place of Presentation
      Washington State Convention Center in Seattle(USA)
    • Year and Date
      2013-06-16 – 2013-06-20
    • Related Report
      2013 Annual Research Report
  • [Presentation] Temporal neocortex shows antero-posterior functional dissociation during retrieval of remote memory.

    • Author(s)
      Watanabe, T., Kimura, H., Hirose, S., Wada, H., Imai, Y., Machida, T., Shirouzu, I., Miyashita, Y. and Konishi, S.
    • Organizer
      The 18th Annual Meeting of Organization of Huma Brain Mapping
    • Place of Presentation
      China National Convention Center Beijing, China
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cell-type-specific optogenetic inhibition of Purkinje cells reveals cerebellar control of blood pressure maintenance during postural alterations.

    • Author(s)
      Tsubota, T., Y. Ohashi, Tamura, K., Yaguchi, M., Matsuyama, M. Sekine, T. and Miyashita, Y.
    • Organizer
      The 35th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya Congress Center
    • Related Report
      2012 Annual Research Report
  • [Presentation] Memory retrieval-related fMRI activity in the macaque posterior parietal cortex.

    • Author(s)
      Miyamoto, K., Osada, T., Adachi, Y., Matsui, T., Kimura, H. M. and Miyashita, Y.
    • Organizer
      The 35th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya Congress Center
    • Related Report
      2012 Annual Research Report
  • [Presentation] Advances in experimental and theoretical approaches to understanding functional architecture of neural circuits: Granger causality analysis in monkey temporal cortex during perceptual and memory task.

    • Author(s)
      Hirabayashi, T., Takeuchi, D., Tamura, K. and Miyashita, Y.
    • Organizer
      The 35th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya Congress Center
    • Related Report
      2012 Annual Research Report
  • [Presentation] Antero-posterior functional difference in the temporal neocortex during retrieval of remote memory.

    • Author(s)
      Watanabe, T., Kimura, H.M., Hirose, S., Wada, H., Imai, Y., Machida, T., Shirouzu, I., Miyashita, Y. and Konishi, S. 5. Watanabe, T., Kimura, H.M., Hirose, S., Wada, H., Imai, Y., Machida, T., Shirouzu, I., Miyashita, Y. and Konishi, S.
    • Organizer
      The 35th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      Nagoya Congress Center
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cerebellar regulation of blood pressure during postural alterations revealed by Purkinje cell-specific optogenetic inhibition.

    • Author(s)
      Tsubota, T., Ohashi, Y., Tamura, K., Yaguchi, M., Matsuyama, M., Sekine, T. and Miyashita, Y.
    • Organizer
      The 42nd annual meeting of the Society for Neuroscience
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center, U.S.A.
    • Related Report
      2012 Annual Research Report
  • [Presentation] Applying optogenetics to macaque deep brain structures: Development of a glass-coated tungsten optrode enclosing optical fibers.

    • Author(s)
      Tamura, K., Ohashi, Y., Tsubota, T., Takeuchi, D., Hirabayashi, T., Yaguchi,M.,Matsuyama, M., Sekine, T. and Miyashita, Y.
    • Organizer
      The 42nd annual meeting of the Society for Neuroscience
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center, U.S.A.
    • Related Report
      2012 Annual Research Report
  • [Presentation] Convergence of category-specific information in the temporal neocortex during retrieval of remote memory.

    • Author(s)
      Watanabe, T., Kimura, H.M., Hirose, S., Wada, H., Katsura, M., Imai, Y., Machida, T., Shirouzu, I., Miyashita, Y. and Konishi, S.
    • Organizer
      The 42nd annual meeting of the Society for Neuroscience
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center, U.S.A.
    • Related Report
      2012 Annual Research Report
  • [Presentation] Human association cortex is composed of functionally relevant micro-modules: a high-resolution fMRI study using resting-state functional connectivity.

    • Author(s)
      Hirose, S., Watanabe, T., Wada, H., Imai, Y., Machida, T., Shirouzu, I., Miyashita, Y. and Konishi, S.
    • Organizer
      The 90th Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Tower Hall Funabori Tokyo
    • Related Report
      2012 Annual Research Report
  • [Presentation] Differences in Anatomical Basis of Local vs Global Resting State Networks.

    • Author(s)
      Adachi, Y. and Miyashita, Y.
    • Organizer
      The 19th Annual Meeting of the Organization for Human Brain Mapping.
    • Place of Presentation
      Washington State Convention Center in Seattle, U.S.A.
    • Related Report
      2012 Annual Research Report
  • [Remarks] Miyashita Lab.

    • URL

      http://www.physiol.m.u-tokyo.ac.jp/

    • Related Report
      2016 Annual Research Report
  • [Remarks] Department of Physiology Miyashita Lab.

    • URL

      http://www.physiol.m.u-tokyo.ac.jp/

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
  • [Remarks] Department of Physiology Miyashita Lab.

    • URL

      http://www.physiol.m.u-tokyo.ac.jp/index.html

    • Related Report
      2012 Annual Research Report

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Published: 2012-11-27   Modified: 2019-07-29  

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