| Budget Amount *help |
¥29,770,000 (Direct Cost: ¥22,900,000、Indirect Cost: ¥6,870,000)
Fiscal Year 2015: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2014: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
Fiscal Year 2013: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2012: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Outline of Final Research Achievements |
Human imaging studies have suggested that dysfunction of the amygdala-anterior cingulate loop may cause affective disorder and anxiety disorder. However, the existence and function of the loop are still unknown. In the present study, we examined the neural connectivity and responsiveness of the anterior cingulate cortex using monkeys, which have brain structures and function similar to those of humans. We found that, unlike other frontal areas, the anterior cingulated cortex has dense connections with temporal areas related to emotional behavior, such as the temporal pole, perirhinal cortex, and the amygdala. We also found that some anterior cingulate neurons responded to emotional stimuli, such as photos of other monkey faces and snakes. These characteristics of the anterior cingulate may form the basis of its function of emotional regulation.
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