The mechanisms for deterioration of thermoregulatory responses in older people and the counter measure against their heat illness
| Project/Area Number |
24240089
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Shinshu University |
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Principal Investigator |
NOSE Hiroshi 信州大学, 学術研究院医学系, 教授 (40128715)
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| Co-Investigator(Kenkyū-buntansha) |
KAMIJO Yoshi-ichiro 信州大学, 学術研究院医学系, 講師 (40372510)
OKAZAKI Kazunobu 大阪市立大学, 都市健康・スポーツ研究センター, 准教授 (70447754)
HIGUCHI Keiichi 信州大学, 学術研究院医学系, 教授 (20173156)
TANIGUCHI Shun'ichiro 信州大学, 学術研究院医学系, 教授 (60117166)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥47,710,000 (Direct Cost: ¥36,700,000、Indirect Cost: ¥11,010,000)
Fiscal Year 2014: ¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Fiscal Year 2013: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
Fiscal Year 2012: ¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000)
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| Keywords | スポーツ生理学 / 運動生理学 / 体温調節能 / 血液量 / インシュリン / 中高年者 / 暑熱耐性 / 熱中症予防 / 生活習慣病 / 遺伝子修飾 / 運動トレーニング / 糖質・乳蛋白質 / 糖質・乳タンパク質 |
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| Outline of Final Research Achievements |
We examined any merits of the supplementation of a mixture of carbohydrate and protein during exercise training. First, we divided older men into 2 groups; carbohydrate + protein (Pro-CHO) and carbohydrate (CHO) supplementation groups. After 2-mo training, we found that thermoregulatory responses more improved with more increases in plasma volume and albumin content in Pro-CHO than CHO but arterial blood pressure decreased in both groups. Second, we divided older women into 3 groups; control (CNT), low (L-Pro-CHO), and high carbohydrate + protein (H-Pro-CHO) supplementation during interval walking training. After 5-mo training, we found that muscle strength, plasma volume, and inflammatory genes methylation increased more in H-Pro-CHO than CNT. In addition, the inter-individual variation of renal Na+ reabsorption rate in response to plasma insulin concentration during OGTT was smaller in H-Pro-CHO than in CNT. Thus, the supplementation might enhance the benefits of exercise training.
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Report
(4 results)
Research Products
(43 results)
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[Journal Article] NFkB2 gene as anoble candidate epidemiologically responding to interval walking training.2015
Author(s)
Zhang Y, Hashimoto S, Fujii C, Hida S, Ito K, Matsumura T, Sakaizawa T, Morikawa M, Masuki S, Nose H, Higuchi K, Nakajima K, Taniguchi S
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Journal Title
Int. J. Sports. Med.
Volume: in press
Issue: 09
Pages: 769-775
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] The factors affecting adherence to a long-term interval walking training program in middle-aged and older people2015
Author(s)
Masuki S, Mori M, Tabara Y, Sakurai A, Hashimoto S, Morikawa M, Miyagawa K, Sumiyoshi E, Miki T, Higuchi K, and Nose H
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Journal Title
J. Appl. Physiol.
Volume: 118
Issue: 5
Pages: 595-603
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Book] 浮腫2014
Author(s)
能勢 博
Total Pages
315
Publisher
医薬ジャーナル社
Related Report
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