Hypervalent Iodine-Catalyzed Organic Reactions Directed towards GSC
| Project/Area Number |
24245020
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (A)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Nagoya University |
|---|
Principal Investigator |
Ishihara Kazuaki 名古屋大学, 工学(系)研究科(研究院), 教授 (40221759)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
Uyanik Muhammet 名古屋大学, 大学院工学研究科, 助教 (20452188)
|
|---|
| Project Period (FY) |
2012-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥45,890,000 (Direct Cost: ¥35,300,000、Indirect Cost: ¥10,590,000)
Fiscal Year 2014: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2013: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2012: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
|
|---|
| Keywords | 超原子価ヨウ素 / 不斉触媒 / ヨウ素触媒 / 脱芳香族化反応 / 脱水素カップリング / 酸化的カップリング / キノール / 酸化反応 / 触媒 / ヨウ素 / 超原子価 / 次亜ヨウ素酸塩 / 次亜塩素酸塩 / 触媒・科学プロセス / 合成化学 / 有機化学 / 環境対応 / 有機工業化学 / 触媒・化学プロセス |
|---|
| Outline of Final Research Achievements |
Hypervalent iodine compounds are very attractive as alternative resources for heavy metal oxidants green & sustainable chemistry. However, iodine is also a rare element resource in halogen elements. Therefore, the catalytic use of iodine sources are much better from a standpoint of element strategy. Thus, we developed several designer iodine catalysts for selective oxidative reactions: (1) chiral quaternary ammonium hypoiodide-catalyzed enantioselective dehydogenative coupling reactions to provide O, and N-heterocycles, (2) chiral iodosoarene-catalyzed enantioselective dearomatizations ti provide spirocyclic sompounds, (3) IBS-catalyzed regioselective oxidation of 2-substituted phenols to 1,2-qinols. In particular, 2-silylmethyl substituent of phenols are effecyive for IBS-catalyzed regioselective oxidation.
|
Report
(4 results)
Research Products
(66 results)
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Hypervalent Iodine Catalyses2012
Author(s)
Kazuaki Ishihara
Organizer
The Fifth International Forum on Homogeneous Catalysis
Place of Presentation
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry (SIOC), Shanghai, China
Related Report
Invited
-
[Presentation] Hypervelent Iodine Catalyses2012
Author(s)
Kazuaki Ishihara
Organizer
6th International Meeting on Halogen Chemistry (HALCHEM-VI)
Place of Presentation
Department of Inorganic & Physical Chemistry, Indian Institute of Science, Bangalore 560012, India
Related Report
Invited
-
-
-
-
-
-
-
-
-
