| Budget Amount *help |
¥45,890,000 (Direct Cost: ¥35,300,000、Indirect Cost: ¥10,590,000)
Fiscal Year 2014: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2013: ¥14,950,000 (Direct Cost: ¥11,500,000、Indirect Cost: ¥3,450,000)
Fiscal Year 2012: ¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
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| Outline of Final Research Achievements |
Hypervalent iodine compounds are very attractive as alternative resources for heavy metal oxidants green & sustainable chemistry. However, iodine is also a rare element resource in halogen elements. Therefore, the catalytic use of iodine sources are much better from a standpoint of element strategy. Thus, we developed several designer iodine catalysts for selective oxidative reactions: (1) chiral quaternary ammonium hypoiodide-catalyzed enantioselective dehydogenative coupling reactions to provide O, and N-heterocycles, (2) chiral iodosoarene-catalyzed enantioselective dearomatizations ti provide spirocyclic sompounds, (3) IBS-catalyzed regioselective oxidation of 2-substituted phenols to 1,2-qinols. In particular, 2-silylmethyl substituent of phenols are effecyive for IBS-catalyzed regioselective oxidation.
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