Development of highly atom-efficient addition reactions with catalytic functionalizations
| Project/Area Number |
24245021
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Kyoto University |
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Principal Investigator |
TSUJI Yasushi 京都大学, 工学(系)研究科(研究院), 教授 (30144330)
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| Co-Investigator(Renkei-kenkyūsha) |
FUJIHARA Tetsuaki 京都大学, 大学院工学研究科, 助教 (30374698)
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| Project Period (FY) |
2012-05-31 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥37,570,000 (Direct Cost: ¥28,900,000、Indirect Cost: ¥8,670,000)
Fiscal Year 2014: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
Fiscal Year 2013: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
Fiscal Year 2012: ¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
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| Keywords | カルボニル化合物 / 遷移金属触媒 / 官能基化 / パラジウム触媒 / 銅触媒 / 高選択的反応 / カルボニル基 / 付加反応 / イリジウム触媒 / 酸塩化物 / 高選択的 / アルキン / 脱カルボニル化反応 / 立体選択的 / 位置選択的 |
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| Outline of Final Research Achievements |
Highly selective and efficient functionalizations of unsaturated substrates such as alkynes and 1,2-dienes (allenes) have been developed by utilizing acid chlorides, aldehydes, formamides, and carbon dioxides as functionality sources. Unlike former transformations, proper choice of central metals and ligands of the catalyst prevent loss of the functionalities during the catalytic reactions. Further addition of hydrosilanes, silylboranes, and diboranes to the catalytic systems realized reductive, silylative, and borylative functionalizations.
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Report
(4 results)
Research Products
(24 results)
