Genetic and molecular mechanism for information processing in the brain of the silkworm, Bombyx mori
| Project/Area Number |
24248011
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied entomology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SHIMADA Toru 東京大学, 農学生命科学研究科, 教授 (20202111)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥45,110,000 (Direct Cost: ¥34,700,000、Indirect Cost: ¥10,410,000)
Fiscal Year 2014: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Fiscal Year 2013: ¥14,170,000 (Direct Cost: ¥10,900,000、Indirect Cost: ¥3,270,000)
Fiscal Year 2012: ¥20,800,000 (Direct Cost: ¥16,000,000、Indirect Cost: ¥4,800,000)
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| Keywords | 鱗翅目 / 産卵行動 / 吐糸・営繭行動 / 光周反応 / 休眠 / 遺伝子ノックアウト / RNA-seq / 営繭行動 / 配偶行動 / 脳機能 / 腹部神経節 / 連鎖解析 / 摂食行動 |
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| Outline of Final Research Achievements |
To understand the brain function in lepidopteran insects, the silkworm mutants for the brain responses to environment or situation are invaluable genetic resources. In this project, strain "u80", which shows abnormal oviposition behavior without copulation, the mutant "Fl", which makes malformed cocoons because of abnormal spinning behavior, and the variant "Lm(e)", which shows photoperiodism in larval stages for diapause properties in the next generation, were utilized for genetic analyses, i.e. trials for positional clonings. As the results, the responsible regions for u80, Fl, and Lm(e) were localized on limited regions on chromosomes 10, 7, and 1, respectively.
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Report
(4 results)
Research Products
(9 results)
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[Journal Article] Mutation of a novel ABC transporter gene is responsible for the failure to incorporate uric acid in the epidermis of ok mutants of the silkworm, Bombyx mori2013
Author(s)
Lingyan Wang, Takashi Kiuchi, Tsuguru Fujii, Takaaki Daimon, Muwang Lia, Yutaka Banno, Shingo Kikuta, Takahiro Kikawada, Susumu Katsuma, Toru Shimada
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Journal Title
Insect Biochemistry and Molecular Biology
Volume: 43
Issue: 7
Pages: 562-571
DOI
Related Report
Peer Reviewed
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