| Project/Area Number |
24256006
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 海外学術 |
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| Research Field |
Surgical dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
FURUKAWA Hiroo (NIIMI Teruyuki) 愛知学院大学, 心身科学部, 教授 (70291763)
MINAMI Katsuhiro 愛知学院大学, 歯学部, 講師 (70346162)
SAKAI Eiko 愛知学院大学, 心身科学部, 教授 (80148254)
YAMANAKA Katsumi 名古屋学芸大学, 栄養学部, 教授 (40351209)
OTSUKA Takanobu 名古屋市立大学, 医学研究科, 教授 (10185316)
SENDA Akira 愛知学院大学, 歯学部, 教授 (80097584)
HATTORI Masami 愛知学院大学, 歯学部, 教授 (50113072)
MAEDA Hatsuhiko 愛知学院大学, 歯学部, 教授 (30175591)
INOUE Makoto 愛知学院大学, 薬学部, 教授 (50191888)
IKEDA Yayoi 愛知学院大学, 歯学部, 教授 (00202903)
SHIMAZAKI Yoshihiro 愛知学院大学, 歯学部, 教授 (10291519)
MITANI Akio 愛知学院大学, 歯学部, 教授 (50329611)
NOMOTO Shuji 愛知学院大学, 歯学部, 教授 (40300967)
TAKEBE Jun 愛知学院大学, 歯学部, 教授 (50295995)
FUJITANI Morioki 愛知学院大学, 歯学部, 教授 (60190055)
YOSHIDA Waka 愛知学院大学, 歯学部, 講師 (10513210)
HAYAKAWA Toko 愛知学院大学, 心身科学部, 講師 (90609710)
IMURA Hideto 愛知学院大学, 歯学部, 講師 (10513187)
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| Research Collaborator |
YAMAUCHI Fuko
NAGATA Erika
AKASHI Junko
ITO Masaaki
NATSUME Nagana
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| Project Period (FY) |
2012-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2016: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Keywords | モンゴル / 口唇裂 / 口蓋裂 / 乳製品 / 予防 / 先天異常の予防 / チーズの効果 / 疫学研究 |
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| Outline of Final Research Achievements |
(1)Epidemiological investigation of the relationship between the eating habits and occurrence of cleft lip and/or palate (CL/P) in Mongolia. Significant differences were observed in the intake of dairy products, meat and eggs by mothers of CL/P patients from that by mothers of normal children, suggesting the intake of those food may have the effect of preventing the occurrence of CL/P.Smoking habits of mothers of CL/P patients were also different from mothers of children without CL/P. There could be a possibility that smoking habits affect the occurrence of CL/P.
(2)Confirmation of the effect of Mongolian cheese on occurrence of CL/P in A/J mice. The percentage of dead fetuses was 7.1% in the experimental group of A/J mice fed with Mongolian cheese, which was significantly 20.6% in the control group.As for incidence of CL/P, the incidence of CL/P in the experimental group was 6.5%, which was significantly lower than 11.7% of that in the control group (p=0.041).
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