Intracortical mechanism of go/no-go movements
| Project/Area Number |
24300143
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | Tamagawa University |
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Principal Investigator |
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
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| Keywords | 神経科学 / 神経生理学 / 大脳皮質 / 運動発現 / 脳・神経 / 生理学 / ラット / 運動野 / 神経細胞 |
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| Outline of Final Research Achievements |
In this study, we examined how cortical pyramidal neurons and interneurons encode information for motor functions in rats performing a behavioral task requiring do or do not execute a motor action intentionally. We analyzed multi-neuronal activity that was recorded from the forelimb areas of primary and secondary motor cortices through 16 or 32ch multichannel silicon probe(s) during their task performance. We found that basal spike properties and functional activity are very similar between these two motor areas, but the functional activity was more adaptive in the secondary motor cortex than the primary one. These observations suggest that the secondary motor cortex may be functionally differentiated to integrate motor information with internal state information for an adaptation to goal-directed behaviors.
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Report
(5 results)
Research Products
(34 results)
