Treatment Time Reduction in Ultrasound Thermal Therapy using Cavitation Bubbles in a Large Region
| Project/Area Number |
24300178
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Tohoku University |
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Principal Investigator |
YOSHIZAWA Shin 東北大学, 工学(系)研究科(研究院), 准教授 (30455802)
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| Co-Investigator(Kenkyū-buntansha) |
UMEMURA Shin-ichiro 東北大学, 大学院医工学研究科, 教授 (20402787)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2014: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2012: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Keywords | 超音波治療 / キャビテーション / HIFU / マイクロバブル / 非線形超音波 |
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| Outline of Final Research Achievements |
High-intensity focused ultrasound has attracted much attention as a modality for the noninvasive thermal treatment of cancer. However, it has a problem of long treatment time. The objective of this study is to develop a method for the ultrasonic heating with high efficiency by using cavitation clouds generated in a large region. Cavitation clouds were generated and used in a large region by electronically scanning HIFU focus in a plane perpendicular to the HIFU propagation direction. Applying this method to a tissue mimicking phantom, the temperature rise measured with a thermocouple was two to three times of that without cavitation generation. The coagulation volume of chicken breast tissues showed a high efficiency of the developed method for a HIFU thermal treatment.
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Report
(4 results)
Research Products
(14 results)
