Development of pulmonary rehabilitation improving prognosis by focusing on cough and swallowing functions.
| Project/Area Number |
24300187
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Toho University (2013-2015)
Tohoku University (2012) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KOHZUKI Masahiro 東北大学, 医学系研究科, 教授 (70234698)
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| Co-Investigator(Renkei-kenkyūsha) |
OSAKA Ken 東北大学, 歯学研究科, 教授 (60300935)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2012: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Keywords | 咳 / 嚥下障害 / 咳嗽障害 / 誤嚥性肺炎 / 呼吸リハビリテーション / 間質性肺炎 / Somatic cough syndrome / Unexplained cough / Ｄｙｓｔｕｓｓｉａ / Ａｓｐｉｒａｔｉｏｎ ｐｎｅｕｍｏｎｉａ / 咳嗽 / 咳衝動 / 性差 / 咳嗽評価法 / 咳反射 / 振動刺激 / 呼吸困難 / 痛み / TRPV1 / TRPA1 / 医療費 / 予後 |
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| Outline of Final Research Achievements |
In order to improve the prognosis of the respiratory patients who received the pulmonary rehabilitation, we developed the efficient rehabilitation program focusing on dyspnea, dysphagia and dystussia. We developed the several methods to inhibit cough in patients with excessive cough. We also developed the methods to ameliorate dyspnea in respiratory patients with shortness of breathing. In addition, we developed the methods to restore the functioning cough in patients with aspiration pneumonia. Using the methods, we found the paradigm shift of pulmonary rehabilitation. Program in interstitial pneumonia is to recover swallowing function and inhibit cough reflex sensitivity. Program in COPD and aspiration pneumonia is to slow the functional decline “dementia → dysphagia → dystussia → atussia → silent aspiration.” Atussia is ultimate dysfunction of cough physiology, and aspiration with atussia is called silent aspiration, which leads to the development of aspiration pneumonia.
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Report
(5 results)
Research Products
(27 results)
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[Journal Article] Royal jelly prevents the progression of sarcopenia in aged mice in vivo and in vitro2013
Author(s)
Kaijun Niu, Hui Guo, Yinting Guo, Satoru Ebihara, Masanori Asada, Takashi Ohrui, Katsutoshi Furukawa, Masakazu Ichinose,Kazuhiko Yanai, Yukitsuka Kudo, Hiroyuki Arai, Tatsuma Okazaki, and Ryoichi Nagatomi
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Journal Title
Journal of Gerontology: Biological Sciences
Volume: (掲載確定)
Issue: 12
Pages: 1482-1492
DOI
Related Report
Peer Reviewed
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[Journal Article] Impact of blunted perception of dyspnea on medical care use and expenditure, and mortality in elderly people.2012
Author(s)
Ebihara S, Niu K, Ebihara T, Kuriyama S, Hozawa A, Ohmori-Matsuda K, Nakaya N, Nagatomi R, Arai H, Kohzuki M, Tsuji I.
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Journal Title
Front Physiol.
Volume: 3
Pages: 238-238
DOI
Related Report
Peer Reviewed
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