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Skeletal muscle hypertrophy induced by KAATSU training and its molecular mechanisms and application to older adults with sarcopenia

Research Project

Project/Area Number 24300189
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionDokkyo Medical University (2015)
The University of Tokyo (2012-2014)

Principal Investigator

Nakajima Toshiaki  獨協医科大学, 医学部, 教授 (50227790)

Co-Investigator(Renkei-kenkyūsha) KANO YUTAKA  電気通信大学, 情報理工学(系)研究科, 教授 (90293133)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2012: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Keywordssarcopenia / anti-aging / muscle hypertrophy / Kaatsu training / rat skeletal muscle / 高齢者 / 筋蛋白質合成系 / ミトコンドリア / Sarcopenia / Anti-aging / Muscle hypertrophy / 筋酸素分圧 / 筋蛋白合成 / KAATSU training / mTOR / 筋タンパク合成
Outline of Final Research Achievements

Sarcopenia, the loss of muscle mass, is an important problem in the older population. We have performed several clinical and basic researches. (1) Effects of KAATSU training using low-intensity resistance exercise, using either resistance machines or elastic bands on muscle strength/mass and its safety in older adults. We found that KAATSU training, even using elastic bands for resistance, enhanced muscle activation and increases muscle strength and mass in older subjects. (2) Basic studies using rat KAATSU model. Acute low-intensity isometric electrical contractions under restrction of muscle blood flow (RMBF) significantly decreased microvascular pO2, and enhanced phosphorylation of mTOR signaling including ribosomal protein S6, compared with control. And, this EMS stimulation under RMBF significantly enhanced muscle strength/mass and enhanced skeletal muscle oxidative capacity, glucose/monocarboxylate transporter, and mitochondrial biogenesis in rat KAATSU model.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (55 results)

All 2016 2015 2014 2013 2012 Other

All Journal Article (19 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 19 results,  Acknowledgement Compliant: 4 results,  Open Access: 2 results) Presentation (34 results) (of which Int'l Joint Research: 10 results,  Invited: 14 results) Book (2 results)

  • [Journal Article] Repetitive restriction of muscle blood flow enhances mTOR signaling pathways in a rat model.2016

    • Author(s)
      Nakajima T, Yasuda T, Koide S, Yamasoba T, Obi S, Toyoda S, Sato Y, Inoue T, KanoY
    • Journal Title

      Heart Vessels

      Volume: In press Issue: 10 Pages: 1685-1695

    • DOI

      10.1007/s00380-016-0801-6

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Effects of low-load, elastic band resistance training combined with blood flow restriction on muscle size and arterial stiffness in older adults.2015

    • Author(s)
      Yasuda T, Fukumura K, Uchida Y, Koshi H, Iida H, Masamune K, Yamasoba T, Sato Y, Nakajima T.
    • Journal Title

      The Journals of Gerontology, Series A: Biological Sciences

      Volume: 印刷中 Issue: 8 Pages: 950-958

    • DOI

      10.1093/gerona/glu084

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effects of detraining after blood flow restricted elastic band training on muscle adaptations and arterial stiffness in older adults.2015

    • Author(s)
      Yasuda T, Fukumura K, Iida H, Nakajima T.
    • Journal Title

      SpringerPlus

      Volume: 4 Issue: 1 Pages: 348-348

    • DOI

      10.1186/s40064-015-1132-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Effect of low-load resistance exercise to volitional exhaustion on muscle swelling: Comparison of blood flow restriction and non-blood flow restriction.2015

    • Author(s)
      Yasuda T, Fukumura K, Iida H, Nakajima T.
    • Journal Title

      European Journal of Applied Physiology

      Volume: 115 Issue: 5 Pages: 919-926

    • DOI

      10.1007/s00421-014-3073-9

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Relationship between chronotropic incompetence and β-blockers based on changes in chronotropic response during cardiopulmonary exercise testing.2015

    • Author(s)
      Takano N, Takano H, Fukuda T, Kikuchi H, Oguri G, Fukumura K, Iwasawa K, Nakajima T.
    • Journal Title

      International Journal of Cardiology Heart & Vessels

      Volume: 6 Pages: 12-18

    • DOI

      10.1016/j.ijcha.2014.11.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Angiogenic potential of early and late outgrowth endothelial progenitor cells is dependent on the time of emergence.2015

    • Author(s)
      Minami Y, Nakajima T, Ikutomi M, Morita T, Komuro I, Sata M, Sahara M.
    • Journal Title

      Int J Cardiol

      Volume: 186 Pages: 305-314

    • DOI

      10.1016/j.ijcard.2015.03.166

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Diverse Contribution of Bone Marrow-derived Late-outgrowth Endothelial Progenitor Cells to Vascular Repair under Pulmonary Arterial Hypertension and Arterial Neointimal Formation.2015

    • Author(s)
      Ikutomi M, Sahara M, Nakajima T, Minami Y, Morita T, Hirata Y, Komuro I, Nakamura F, Sata M.
    • Journal Title

      J Mol Cell Cardiol.

      Volume: 82 Pages: 121-135

    • DOI

      10.1016/j.yjmcc.2015.07.019

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Thermo-sensitive Transient Receptor Potential Vanilloid (TRPV) Channels Regulate IL-6 Expression in Mouse Adipocytes.2015

    • Author(s)
      Kikuchi H, Oguri G, Yamamoto Y, Takano N, Tanaka T, Takahashi M, Nakamura F, Yamasoba T, Komuro I, Obi S, Nakajima, T.
    • Journal Title

      Cardiovascular Pharmacology

      Volume: 4 Issue: 04 Pages: 4-4

    • DOI

      10.4172/2329-6607.1000156

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 心臓リハビリテーションの費用効用分析2015

    • Author(s)
      原湖南、福村和也、小林廉毅、小室一成、中島敏明
    • Journal Title

      心臓リハビリテーション (JJCR)

      Volume: 20

    • NAID

      40021137419

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 先制予防を可能にする実践的試み:加圧トレーニング。2015

    • Author(s)
      中島敏明、福村和也、安田智洋
    • Journal Title

      心臓リハビリテーション(JJCR)20: 51-55, 2015.

      Volume: 20 Pages: 51-55

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Muscle size and arterial stiffness after blood flow-restricted low-intensity resistance training in older adults.2014

    • Author(s)
      Yasuda Y, Fukumura K, Fukuda T, Uchida Y, Iida H, Meguro M, Sato Y, Yamasoba T, Nakajima T.
    • Journal Title

      Scand J Med Sci Sports

      Volume: 24 Issue: 5 Pages: 799-806

    • DOI

      10.1111/sms.12087

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of low-intensity, elastic band resistance exercise combined with blood flow restriction on muscle activation.2014

    • Author(s)
      Yasuda T, Fukumura K, Fukuda T, Iida H, Imuta H, Sato Y, Yamasoba T, Nakajima T.
    • Journal Title

      Scandinavian Journal of Medicine and Science in Sports

      Volume: 24 Pages: 55-61

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of detraining after blood flow restricted low-intensity training on muscle size and strength in older adults2014

    • Author(s)
      Yasuda T, Fukumura K, Sato Y, Yamasoba T, Nakajima T
    • Journal Title

      Aging Clinical and Experimental Research

      Volume: (in press) Issue: 5 Pages: 561-564

    • DOI

      10.1007/s40520-014-0208-0

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hemostatic and inflammatory responses to blood flow-restricted exercise in patients with ischemic heart diseases : a pilot study.2013

    • Author(s)
      Madarame H, Kurano M, Fukumura K, Fukuda T, Nakajima T
    • Journal Title

      Clin Physiol Funct Imaging

      Volume: 33 Issue: 1 Pages: 11-17

    • DOI

      10.1111/j.1475-097x.2012.01158.x

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cardiac rehabilitation increases exercise capacity with a reduction of oxidative stress.2013

    • Author(s)
      Fukuda T, Kurano M, Fukumura K, Yasuda T, Iida H, Morita T, Yamamoto Y, Takano N, Komuro I, Nakajima T.
    • Journal Title

      Korean Circ J.

      Volume: 43 Issue: 7 Pages: 481-487

    • DOI

      10.4070/kcj.2013.43.7.481

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo imaging of intracellular Ca^<2+> after muscle contractions and direct Ca^<2+> injection in rat skeletal muscle in diabetes2013

    • Author(s)
      Hiroaki Eshima, Yoshinori Tanaka, Takashi Sonobe, Tadakatsu Inagaki, Toshiaki Nakajima, David C. Poole, and Yutaka Kano
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 15;305(6) Issue: 6 Pages: R610-R618

    • DOI

      10.1152/ajpregu.00023.2013

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of low-intensity, elastic band resistance exercise combined with blood flow restriction on muscle activation.2013

    • Author(s)
      Yasuda T, Fukumura K, Fukuda T, Iida H, Imuta H, Sato Y, Yamasoba T, Nakajima T.
    • Journal Title

      Scandinavian Journal of Medicine & Science in Sports

      Volume: 印刷中 Issue: 1 Pages: 55-61

    • DOI

      10.1111/j.1600-0838.2012.01489.x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cardiac rehabilitation decreases plasma pentraxin 3 in patients with cardiovascular diseases.2012

    • Author(s)
      Fukuda T, Kurano M, Iida H, Takano H, Tanaka T, Yamamoto Y, Ikeda K, Nagasaki M, Monzen K, Uno K, Kato M, Shiga T, Maemura K, Matsuda N, Yamashita Y, Hirata Y, Nagai R, Nakajima T.
    • Journal Title

      Eur J Prev Cardiol

      Volume: 19 Issue: 6 Pages: 1393-1400

    • DOI

      10.1177/1741826711422990

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cardiac output response to exercise in chronic cardiac failure patients Role of stroke volume.2012

    • Author(s)
      Fukuda T, Matsumoto A, Kurano M, Takano H, Iida H, Morita T, Yamashita H, Hirata Y, Nagai R, Nakajima T.
    • Journal Title

      Int Heart J

      Volume: 153 Pages: 1293-298

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Skeletal Muscle Hypertrophy Induced by Novel KAATSU Rehabilitation and Prevention of Sarcopenia.2015

    • Author(s)
      Nakajima T
    • Organizer
      KAATSU International Symposium 2015
    • Place of Presentation
      Boston
    • Year and Date
      2015-11-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 血流制限下の電気刺激によるトレーニングによるラット骨格筋各種蛋白発現に及ぼす効果について2015

    • Author(s)
      中島敏明、安田智洋、狩野豊
    • Organizer
      第21回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-07-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 温熱刺激は骨格筋細胞でのインターロイキン6と熱ショック蛋白90αの産生を増大する。2015

    • Author(s)
      小尾正太郎、井上晃男、中島敏明
    • Organizer
      第21回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-07-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 加圧トレーニングの体組成、動脈硬化指標におよぼす影響2015

    • Author(s)
      堤博美、宮内拓史、高尾奈那、川口紗苗、那須加奈子、坂田和房、中島敏明、佐藤義昭、木村穣
    • Organizer
      第21回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-07-18
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Chronic isometric electrical stimulation under blood flow restriction enhances MCT1, GLUT4, and PGC1α protein expression in rat KAATSU model.2015

    • Author(s)
      Nakajima T, Yasuda T, Tomaru T, Kano Y
    • Organizer
      第79回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effects of methyglyoxal on human cardiac fibroblast: Roles of transient receptor potential ankyrin 1 (TRPA1) channels.2015

    • Author(s)
      Oguri A, Nakajima T, Yamamoto Y, Kikuchi H, Takano N, Tanaka T, Komuro I
    • Organizer
      第79回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Thermo-sensitive transient receptor potential vanilloid (TRPV) channels regulate IL-6 expression in mouse adipocytes.2015

    • Author(s)
      Kikuchi H, Nakajima T, Oguri G, Yamamoto Y, Takano N, Tanaka T, Takahashi M, Morita T, Nakamura F, Komuro I.
    • Organizer
      第79回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Effect of elastic-band resistance training combined with blood flow restriction on muscle performance and vascular function in older adults.2015

    • Author(s)
      Yasuda T, Fukumura K, Tomaru T, Nakajima T
    • Organizer
      第79回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Arterial stiffness is increased in patients with age-related macular degeneration.2015

    • Author(s)
      Tomaru T, Nakajima T, Tsutsumi T.
    • Organizer
      第79回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Abnormal frequency power within QRS complex in ischemic cardiomyopathy with ventricular arrhythmia and implications of its causes from computer simulation.2015

    • Author(s)
      Takano N, Tsutsumi T, Okamoto Y, Takano H, Iwasawa K, Tomaru T, Suzuki H, Nakajima T
    • Organizer
      第79回日本循環器学会総会・学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] パネルディスカッション 加圧トレーニングの臨床応用効果と基礎的研究。2014

    • Author(s)
      中島敏明
    • Organizer
      第33回日本臨床運動療法学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-09-06 – 2014-09-10
    • Related Report
      2014 Annual Research Report
  • [Presentation] Skeletal Muscle Hypertrophy Induced by Novel KAATSU Rehabilitation and Prevention of Sarcopenia (Invited Lecture).2014

    • Author(s)
      Nakajima T, Yasuda T, Koide S, Sato Y, Morita T, Tomaru T, Kano Y.
    • Organizer
      International Academy of Cardiology Annual Scientific Sessions 2014 19th World Congrss on Heart Disease
    • Place of Presentation
      Boston, MA, USA)
    • Year and Date
      2014-07-25 – 2014-07-28
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Repetitive Application of Restriction of Muscle Blood Flow Enhances mTOR Signaling Pathways in a Rat Model.2014

    • Author(s)
      Nakajima T, Yasuda T, Koide S, Sato Y, Tomaru T, Kano Y.
    • Organizer
      International Academy of Cardiology Annual Scientific Sessions 2014 19th World Congrss on Heart Disease
    • Place of Presentation
      Boston, MA, USA.
    • Year and Date
      2014-07-24 – 2014-07-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] )シンポジウム2:日本心臓リハビリテーション学会20周年特別企画2.先制予防を可能にする実践的試み。2014

    • Author(s)
      中島敏明
    • Organizer
      第20回日本心臓リハビリテーション学会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] パネルディスカッションポジウム8。心疾患患者に対する加圧トレーニングの理論と実践。2014

    • Author(s)
      中島敏明
    • Organizer
      第20回日本心臓リハビリテーション学会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 血流制限下トレーニングは、骨格筋GLUT4及びMCT1タンパクの発現を亢進する:ラット加圧モデルによる検討。2014

    • Author(s)
      中島敏明、安田智洋、小出誠一郎、佐藤義昭、狩野豊。
    • Organizer
      第20回日本心臓リハビリテーション学会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 血流制限下のセラバンドトレーニングと脱トレーニングが高齢者の筋サイズ、筋力と血管機能に及ぼす影響。2014

    • Author(s)
      安田智洋、福村和也、飯田陽子、輿日登美、佐藤義昭、中島敏明
    • Organizer
      第20回日本心臓リハビリテーション学会
    • Place of Presentation
      京都
    • Year and Date
      2014-07-19 – 2014-07-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] シンポジウム06(運動にアンチエイジング効果はあるか?) 加圧トレーニングの効果。2014

    • Author(s)
      中島敏明
    • Organizer
      第14回日本抗加齢医学会総会
    • Place of Presentation
      大阪、国際会議場
    • Year and Date
      2014-06-06 – 2014-06-08
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Muscle size and arterial compliance after blood flow-restricted low-intensity resistance training in olderly adults.2013

    • Author(s)
      Yasuda T, Fukumura K, Fukuda T, Uchida Y, Iida H, Ohtsuka T, Chujo Y, Meguro M, Sato Y, Nakajima T.
    • Organizer
      The 60th American College of Sports Medicine
    • Place of Presentation
      Indianapolis, Indiana, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Repetitive restriction of muscle blood flow enhances mTOR signalingpathways in rat Kaatsu model.2013

    • Author(s)
      Nakajima T, Yasuda T, Koide S, Takano N, Sato Y, Kano T.
    • Organizer
      The 60th American College of Sports Medicine
    • Place of Presentation
      Indianapolis, Indiana, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Repetitive restriction of muscle blood flow enhances mTOR signaling pathways in a rat model.2013

    • Author(s)
      Nakajima T, Yasuda T, Koide S, Sato Y, Takano N, Yamasoba T, Komuro I, Kano Y.
    • Organizer
      The Scientific Sessions, American Heart Association
    • Place of Presentation
      Dallas, Texas, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] イブニングセミナー 加圧トレーニングの理論と実践2013

    • Author(s)
      中島敏明
    • Organizer
      第86回日本整形外科学会学術総会
    • Place of Presentation
      広島グリーンアリーナリーガロイヤルホテル、広島
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 加圧除圧刺激による筋蛋白質合成系mTORの活性化2013

    • Author(s)
      中島敏明、安田智洋、小出誠一郎、高野奈美、佐藤義昭、小室一成、狩野豊
    • Organizer
      第19回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      仙台国際センター、仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 心臓病患者におけるエラスティクバンドを用いた低強度加圧レジスタンス運動の筋活動に及ぼす効果。2013

    • Author(s)
      福田平、安田智洋、福村和也、飯田陽子、佐藤義昭、小室一成、中島敏明
    • Organizer
      第19回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      仙台国際センター、仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 血流制限下の低強度筋力トレーニングが高齢者の筋サイズ、筋力、血管機能に及ぼす影響。2013

    • Author(s)
      安田智洋、福村和也、福田平、飯田陽子、内田佑介、目黒美葉、佐藤義昭、小室一成、    中島敏明
    • Organizer
      第19回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      仙台国際センター、仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] 糖尿病骨格筋におけるCa2+制御タンパク質の変化。2013

    • Author(s)
      江島弘晃,小出誠一郎, 中島敏明,狩野豊
    • Organizer
      第68回日本体力医学会学術集会
    • Place of Presentation
      日本教育会館・学術総合センター、東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 運動中の筋酸素分圧および肥大因子活性に及ぼす血流制限の影響2013

    • Author(s)
      小出誠一郎,須藤みず紀,佐藤義昭,安田智洋,中島敏明、 狩野豊
    • Organizer
      第68回日本体力医学会学術集会
    • Place of Presentation
      日本教育会館・学術総合センター、東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 中高年者における運動中の心拍出係数、1回拍出係数の動態の検討2013

    • Author(s)
      福田平、松本晃裕、蔵野美葉、安田智洋,飯田陽子、森田敏宏、中島敏明
    • Organizer
      第68回日本体力医学会学術集会
    • Place of Presentation
      日本教育会館・学術総合センター、東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] 長期ディトレーニングが加圧トレーニング後の筋力、筋サイズに及ぼす影響。2013

    • Author(s)
      安田智洋,福村和也、中島敏明
    • Organizer
      第68回日本体力医学会学術集会
    • Place of Presentation
      日本教育会館・学術総合センター、東京
    • Related Report
      2013 Annual Research Report
  • [Presentation] Repetitive Restriction of Muscle Blood Flow Enhances mTOR Signaling Pathways in Rat KAATSU Model.2013

    • Author(s)
      Nakajima T, Yasuda T, Takano N, Koide S, Sato Y, Kano Y
    • Organizer
      第77回日本循環器学会総会・学術集会
    • Place of Presentation
      横浜 パシフィコ横浜
    • Related Report
      2012 Annual Research Report
  • [Presentation] 加圧トレーニングと臨床効果2013

    • Author(s)
      中島敏明
    • Organizer
      第12回日本再生医療学会総会 ランチョンセミナー
    • Place of Presentation
      横浜 パシフィコ横浜(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 運動中の筋酸素分圧、発揮張力、肥大因子タンパク発現に及ぼす血流制限の影響:ラット加圧モデルによる検討。2012

    • Author(s)
      小出誠一郎、狩野豊、須藤みず紀、安田智洋、高野奈美、佐藤義昭、中島敏明
    • Organizer
      第18回日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      大宮 大宮ソニックシティ
    • Related Report
      2012 Annual Research Report
  • [Presentation] 運動中の筋酸素分圧動態に及ぼす血流制限の影響2012

    • Author(s)
      小出誠一郎, 狩野豊, 須藤みず紀, 佐藤義昭, 安田智洋, 中島敏明
    • Organizer
      第67回日本体力医学会学術集会
    • Place of Presentation
      岐阜 長良川国際会議場
    • Related Report
      2012 Annual Research Report
  • [Presentation] ラット加圧モデルにおけるmTORシグナルへの影響について

    • Author(s)
      中島敏明
    • Organizer
      第6回東京アンチエイジングアカデミー
    • Place of Presentation
      キアラ東京、東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Book] 加圧トレーニングの効果2013

    • Author(s)
      中島敏明
    • Publisher
      循環器内科 Cardiology
    • Related Report
      2012 Annual Research Report
  • [Book] トッピクス2.加圧トレーニングと心臓リハビリテーション(まとめ)2013

    • Author(s)
      中島敏明
    • Publisher
      日本心臓リハビリテーション(JJCR)
    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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