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Study of the effect of assisted reproductive technology on benavioral development in children, in the light of the development of the health education program

Research Project

Project/Area Number 24300228
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied health science
Research InstitutionThe University of Tokyo

Principal Investigator

SASAKI TSUKASA  東京大学, 教育学研究科(研究院), 教授 (50235256)

Co-Investigator(Kenkyū-buntansha) OKAI TAKASHI  昭和大学, 医学部, 教授 (40126016)
SHINOHARA KAZUYUKI  長崎大学, 大学病院, 教授 (30226154)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2014: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2013: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2012: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Keywords生殖医療 / 行動発達 / 自然妊娠 / 顕微授精 / 体外受精 / 出産年齢 / 新鮮胚 / 凍結胚 / 行動・情緒発達(CBCL) / 対人反応(SRS) / 顕微受精 / 出生体重 / 保健教育 / 生涯教育 / 行動・情緒発達(CBCL) / 行動・情緒発達 (CBCL) / 発達障害 / 健康教育 / 人工授精
Outline of Final Research Achievements

The present study compared behavioral development, using parent-reported questionnaires, between 4--5 year old children born after assisted reproduction technology (ART) and those of natural conception (NC). Better behavioral deveopment was observed in the ART group than the NC group. No difference was observed when the ART group was divided into subgroups according to the type of ART (ICSI vs. IVS, and fresh vs. frozen embryos) compared with the NC group. These results were summarized in a brochure and distributed to lay people including the participants, asking for their impressions on the results and the brochure. On the basis of the replies, we are currently developing a health literacy program on ART and its effect on behavioral development in the chiidren.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (8 results)

All 2013 2012 Other

All Journal Article (6 results) (of which Peer Reviewed: 5 results) Presentation (1 results) Remarks (1 results)

  • [Journal Article] 生殖補助医療と行動発達2013

    • Author(s)
      島田 隆史、佐々木 司
    • Journal Title

      精神科

      Volume: 第24巻第3号 Pages: 328-334

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Parental age and assisted reproductive technology in autism spectrum disorders, attention deficit hyperactivity disorder, and Tourette syndrome in a Japanese population.2012

    • Author(s)
      Shimada T, Atsushi Kitamoto b, Ayako Todokoro a, AyakaIshii-Takahashi a, Hitoshi Kuwabara c, Soo-YungKim c, Kei-ichiro Watanabe d, Iwao Minowa a, Toshikazu Someya a, Hiroshi Ohtsu e, Osuga Y; Kano Y; Kasai K, Nobumasa Kato N, Sasaki T
    • Journal Title

      Research in Autism Spectrum Disorders

      Volume: 6 Issue: 1 Pages: 500-507

    • DOI

      10.1016/j.rasd.2011.07.010

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electrophysiological Responses in Mothers to Their Own and Unfamiliar Child's Gaze Information.2012

    • Author(s)
      Doi H., Shinohara K.
    • Journal Title

      Brain and Cognition

      Volume: 80(2) Issue: 2 Pages: 266-276

    • DOI

      10.1016/j.bandc.2012.07.009

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Event-Related Potentials Elicited in Mothers by Their Own and Unfamiliar Infants' Faces with Crying and Smiling Expression2012

    • Author(s)
      Doi H, Shinohara K
    • Journal Title

      Neuropsychologia

      Volume: 50(6) Issue: 7 Pages: 1297-1307

    • DOI

      10.1016/j.neuropsychologia.2012.02.013

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Bodily movement of approach is detected faster than that of receding.2012

    • Author(s)
      Doi, H., Shinohara, K.
    • Journal Title

      Psychnomic Bulletin & Review

      Volume: 19(5) Pages: 858-863

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Perceived parental rejection mediates the influence of serotonin transporter gene (5-HTTLPR) polymorphisms on impulsivity in Japanese2012

    • Author(s)
      Nishikawa S, Nishitani S, Fujisawa TX, Noborimoto l, Kitahara T, Takamura T, Shinohara K.
    • Journal Title

      PLoS One.

      Volume: 7(10) Issue: 10 Pages: e47608-e47608

    • DOI

      10.1371/journal.pone.0047608

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 現代の社会生活が発達に与える影響

    • Author(s)
      佐々木 司
    • Organizer
      第40回 日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ
    • Related Report
      2013 Annual Research Report
  • [Remarks] 東京ARTコホート研究

    • URL

      http://art.p.u-tokyo.ac.jp

    • Related Report
      2015 Annual Research Report

URL: 

Published: 2012-04-24   Modified: 2019-07-29  

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