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Identifying older adults physical activity pattern to delay the cognitive decline process

Research Project

Project/Area Number 24300240
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied health science
Research InstitutionNational Center for Geriatrics and Gerontology

Principal Investigator

PARK Hyuntae  独立行政法人国立長寿医療研究センター, 老年学・社会科学研究センター, 研究員 (10506976)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2014: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Keywords認知機能 / 身体活動 / 脳機能 / 加齢 / 軽度認知症 / 高齢者 / 老年症候群 / 認知症 / 加齢・老化 / 運動 / 生活習慣
Outline of Final Research Achievements

Age-related decrements in cognitive function have been atrophy in brain structure and cognitive impairment. However, the relationships between the difference of daily physical activity and brain cortical activity associated with short term memory processes in older adults remain unclear. The current study found that higher physically activity older adults showed increased activation in the middle frontal gyrus, cingulate gyrus, fusiform gyrus, inferior parietal gyrus, supramarginal regions compared with lower physically activity older adults, it appears possible that this finding might be explained by cognitive efficiency. In addition, physical function in the elderly, especially walking speed, was revealed to be an important factor to predict cognitive function and flail or pre-frail and long-term screening and assessment.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (35 results)

All 2015 2014 2013 2012

All Journal Article (17 results) (of which Peer Reviewed: 17 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (14 results) (of which Invited: 4 results) Book (4 results)

  • [Journal Article] Effects of a 12-week healthy-life exercise program on oxidized low-density lipoprotein cholesterol and carotid intima-media thickness in obese elderly women2015

    • Author(s)
      Park J, Park H, Lim S, Park J
    • Journal Title

      J Phys Therapy Sci

      Volume: 27 Pages: 1-5

    • NAID

      130005072247

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Association Between Kidney Function and Cognitive Decline in Community-Dwelling, Elderly Japanese People.2015

    • Author(s)
      Lee S, Shimada H, Park H, Makizako H, Lee S, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T.
    • Journal Title

      J Am Med Dir Assoc.

      Volume: 16 Issue: 4 Pages: 349.e1-349.e5

    • DOI

      10.1016/j.jamda.2014.12.009

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Going outdoors and cognitive function among community-dwelling older adults: Moderating role of physical function.2015

    • Author(s)
      Harada K, Lee S, Park H, Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Suzuki T.
    • Journal Title

      Geriatr Gerontol Int.

      Volume: in press Issue: 1 Pages: 1-5

    • DOI

      10.1111/ggi.12437

    • NAID

      120005997092

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Objectively measured physical activity, brain atrophy, and white matter lesions in older adults with mild cognitive impairment.2015

    • Author(s)
      Doi T, Makizako H, Shimada H, Tsutsumimoto K, Hotta R, Nakakubo S, Park H, Suzuki T.
    • Journal Title

      Experimental Gerontology

      Volume: 62 Pages: 1-6

    • DOI

      10.1016/j.exger.2014.12.011

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Moderate-intensity physical activity, hippocampal volume, and memory in older adults with mild cognitive impairment.2015

    • Author(s)
      Makizako H, Liu-Ambrose T, Shimada H, Doi T, Park H, Tsutsumimoto K, Uemura K, Suzuki T.
    • Journal Title

      J Gerontol A Biol Sci Med Sci.

      Volume: 70 Issue: 4 Pages: 480-6

    • DOI

      10.1093/gerona/glu136

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of enteric-coated lactoferrin supplementation on the immune function of elderly individuals: A randomised, double-blind, placebo-controlled trial2015

    • Author(s)
      H. Kawakami, H. Park, S. Park, H. Kuwata, R.J. Shephard, Y. Aoyagi
    • Journal Title

      International Dairy Journal

      Volume: 47 Pages: 79-85

    • DOI

      10.1016/j.idairyj.2015.02.001

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Depressive symptoms in older adults are associated with decreased cerebral oxygenation of the prefrontal cortex during a trail-making test.2015

    • Author(s)
      Uemura K, Shimada H, Doi T, Makizako H, Park H, Suzuki T.
    • Journal Title

      Arch Gerontol Geriatr.

      Volume: 59 Issue: 2 Pages: 422-428

    • DOI

      10.1016/j.archger.2014.07.003

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Habitual physical activity and milk intake in the elderly2015

    • Author(s)
      Kawakami H, Park H, Park S, Aoyagi Y
    • Journal Title

      Milk Science

      Volume: 63 Pages: 145-153

    • NAID

      130005003552

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Depressive symptoms and cognitive performance in older adults.2014

    • Author(s)
      Shimada H, Park H, Makizako H, Doi T, Lee S, Suzuki T.
    • Journal Title

      Journal of Psychiatric Research

      Volume: 57 Pages: 149-156

    • DOI

      10.1016/j.jpsychires.2014.06.004

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A large, cross-sectional observational study of serum BDNF, cognitive function, and mild cognitive impairment in the elderly.2014

    • Author(s)
      Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Lee S, Park H, Suzuki T
    • Journal Title

      Frontiers in Aging Neuroscience

      Volume: (未定)(印刷中) Pages: 1-9

    • DOI

      10.3389/fnagi.2014.00069

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Brain activation during dual-task walking and executive function among older adults with mild cognitive impairment : a fNIRS study2013

    • Author(s)
      Doi T, Makizako H, Shimada H, Park H, Tsutsumimoto K, Uemura K, Suzuki T
    • Journal Title

      Aging Clin Exp Res

      Volume: 25(5) Issue: 5 Pages: 539-544

    • DOI

      10.1007/s40520-013-0119-5

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between going outdoors daily and activation of the prefrontal cortex during verbal fluency tasks among older adults : a near-infrared spectroscopy study.2013

    • Author(s)
      Makizako H, Doi T, Shimada H, Part H, Uemura K, Yoshida D, Tsutsumimoto K, Anan Y, Suzuki T.
    • Journal Title

      Archives of Gerontology and Geriatrics

      Volume: 56 Issue: 1 Pages: 118-123

    • DOI

      10.1016/j.archger.2012.08.017

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Six-minute walking distance is correlated with memory and brain volume in older adults with mild cognitive impairment : A voxel-based morphometry study2013

    • Author(s)
      Makizako H, Shimada H, Doi T, Park H, Suzuki T.
    • Journal Title

      Dementia and Geriatric Cognitive Disorders Extra

      Volume: 3(1) Issue: 1 Pages: 223-32

    • DOI

      10.1159/000354189

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Combined Prevalence of Frailty and Mild Cognitive Impairment in a Population of Elderly Japanese People.2013

    • Author(s)
      Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Ito T, Lee S, Park H, Suzuki T.
    • Journal Title

      J Am Med Dir Assoc.

      Volume: 14 Pages: 518-518

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effectiveness of rehabilitation based on recreational activities: A systematic review2013

    • Author(s)
      Kamioka H, et al
    • Journal Title

      World Journal of Meta-Analysis

      Volume: 1 Issue: 1 Pages: 27-46

    • DOI

      10.13105/wjma.v1.i1.27

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Performance-based assessments and demand for personal care in older Japanese people : a cross-sectional study2013

    • Author(s)
      Shimada H, Suzuki T, Suzukawa M, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Ito T, et al
    • Journal Title

      BMJ Open

      Volume: 3(4) Issue: 4 Pages: 1-7

    • DOI

      10.1136/bmjopen-2012-002424

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of multicomponent exercise on cognitive function in older adults with amnestic mild cognitive impairment : A randomized controlled trial.2013

    • Author(s)
      Suzuki T, Shimada H, Makizako H, Doi T, Yoshida D, Tsutsumimoto K, Anan Y, Uemura K, Lee S, Park H.
    • Journal Title

      BMC Neurology

      Volume: 12 Issue: 1 Pages: 128-128

    • DOI

      10.1186/1471-2377-12-128

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Sensitive task measure of memory function on the story recall test in patients with mild cognitive impairment and mild Alzheimer's disease2015

    • Author(s)
      Park H, Sohn SW, Park JH, Park H
    • Organizer
      Alzheimer's Association International Conference
    • Place of Presentation
      Washinton DC, USA
    • Year and Date
      2015-07-18 – 2015-07-23
    • Related Report
      2014 Annual Research Report
  • [Presentation] Habitual physical activity and efficiency of cognitive networks during memory task in older adults2015

    • Author(s)
      Park H, Shimada H, Makizako H, Lee S, Doi T, Thuthumimoto K, Lee S, Harada K, Bae S, Suzuki T
    • Organizer
      Organization for Human Brain Mapping
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2015-06-14 – 2015-06-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] Health benefits of dancing, exercise and physical activity.2014

    • Author(s)
      Park H.
    • Organizer
      2014 Asian Game International Sports Science Conference
    • Place of Presentation
      Inchon,Korea
    • Year and Date
      2014-08-20 – 2014-08-22
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] EFFECTS OF MULTICOMPONENT EXERCISE IN OLDER ADULTS WITH MILD COGNITIVE IMPAIRMENT2014

    • Author(s)
      Hiroyuki Shimada, Hyuma Makizako, Takehiko Doi, Hyuntae Park, Kota Tsutsumimoto, Takao Suzuki
    • Organizer
      Alzheimer's Association International Conference
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2014-07-12 – 2014-07-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] Objectively Measured Physical Activity And Calcaneal Bone Health In Older Japanese Adults: The Nakanojo Study.2013

    • Author(s)
      Park H, Shephard RJ, Park S, Aoyagi Y.
    • Organizer
      3rd International Conference on Ambulatory Monitoring of Physical Activity and Movement
    • Place of Presentation
      Massachusetts(アメリカ)(発表確定)
    • Year and Date
      2013-06-17
    • Related Report
      2012 Annual Research Report
  • [Presentation] Objectively Measured Physical Activity And Appendicular Lean Tissue In Older Japanese Adults: The Nakanojo Study.2013

    • Author(s)
      Shephard RJ, Park H, Park S, Aoyagi Y.
    • Organizer
      3rd International Conference on Ambulatory Monitoring of Physical Activity and Movement
    • Place of Presentation
      Massachusetts(アメリカ)(発表確定)
    • Year and Date
      2013-06-17
    • Related Report
      2012 Annual Research Report
  • [Presentation] Active living communities: promoting health through physical activities.2013

    • Author(s)
      Hyuntae Park
    • Organizer
      WHO Global Forum on Innovation for Ageing Populations
    • Place of Presentation
      kobe international conference center, 神戸
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Activity living Communities: Promoting physical activity for brain health and healthy aging2013

    • Author(s)
      Hyuntae Park
    • Organizer
      International Symposium on Geriatrics and Gerontology
    • Place of Presentation
      Aichi Health Praza Hall、愛知
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Physical Activity, Lifestyle and Cognitive Function.2013

    • Author(s)
      Hyuntae Park
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics
    • Place of Presentation
      COEX Convention & Exhibition Center, Seoul, Korea
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Prevention of Cognitive Decline Among The Commnity Elderly Women.2013

    • Author(s)
      Suzuki T, Yoshida D, Makisako H, Park H, Lee S, Shimada H.
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics
    • Place of Presentation
      COEX Convention & Exhibition Center, Seoul, Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Volunteer activity and functional capacity among community-dwelling older adults in Japan: A 3 year longitudinal study.2013

    • Author(s)
      Lee S, Saito T, Park H, Shimada H, Kai I
    • Organizer
      The 20th IAGG World Congress of Gerontology and Geriatrics
    • Place of Presentation
      COEX Convention & Exhibition Center, Seoul, Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Physical activity and musculoskeletal health in older adults.2012

    • Author(s)
      Park H
    • Organizer
      (Active Life) The 7th International Sport Science Symposium
    • Place of Presentation
      早稲田大学東伏見キャンパス(東京都)(招待講演)
    • Year and Date
      2012-09-03
    • Related Report
      2012 Annual Research Report
  • [Presentation] Physical activity, lifestyle and cognitive function.2012

    • Author(s)
      Park H
    • Organizer
      International Association of Gerontology and Geriatrics
    • Place of Presentation
      ソウル(韓国)
    • Year and Date
      2012-06-23
    • Related Report
      2012 Annual Research Report
  • [Presentation] Habitual Physical Activity is Associated With Cognitive Function And The Risk Factors For Hip Fracture In Older Adults.2012

    • Author(s)
      Park H. Kwon Y, Kim E, Park J, Park S.
    • Organizer
      American College of Sports Medicine 59th AnnualMeeting
    • Place of Presentation
      San Francisco(アメリカ)
    • Year and Date
      2012-05-30
    • Related Report
      2012 Annual Research Report
  • [Book] Ecercise for older adults2015

    • Author(s)
      Park H, Kang S, Kim H, Lee K,
    • Total Pages
      258
    • Publisher
      Daehan Media
    • Related Report
      2014 Annual Research Report
  • [Book] Dementia Care and Manegement2015

    • Author(s)
      Park H, Park K
    • Total Pages
      41
    • Publisher
      Seriyun Co. Ltd
    • Related Report
      2014 Annual Research Report
  • [Book] Environmental factors and Exercise Science2014

    • Author(s)
      Park H, Park S
    • Total Pages
      180
    • Publisher
      Doang-A Publishing
    • Related Report
      2014 Annual Research Report
  • [Book] Healt Care and Management2014

    • Author(s)
      Park H, Kim E, Kwon Y, Jung H, Park S
    • Total Pages
      261
    • Publisher
      Dong-A Publishing
    • Related Report
      2014 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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