| Project/Area Number |
24310085
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Ibaraki University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
SATO Masahide 宇都宮大学, 工学研究科, 准教授 (10261504)
SUZUKI Noboru 宇都宮大学, 工学研究科, 教授 (40134259)
GONDA Kohsuke 東北大学, 医学系研究科, 教授 (80375435)
GONDA Kohsuke 東北大学, 医学系研究科, 教授 (90203710)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥20,800,000 (Direct Cost: ¥16,000,000、Indirect Cost: ¥4,800,000)
Fiscal Year 2014: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
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| Keywords | ナノ粒子 / カプセル / コア－シェル / 造影剤 / 画像医療診断 / 分散凝集 / 液相法 / カプセル化 / シリカ / Au / ゾル-ゲル / 医療画像診断 / 表面修飾 |
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| Outline of Final Research Achievements |
Luminescent semiconductor nanoparticles (QDs) are expected to be used as a fluorescent marker for medical diagnostics. Among various methods for reducing harm of Cd contained in QD, encapsulating, or coating of contrast agents with materials inert to living bodies is a good candidate. Meanwhile, materials that have both properties of fluorescence and X-ray absorption will be used for imaging targets by multiple techniques. The present work developed methods for preparing the QDs coated with silica (QD/SiO2), the QD/SiO2 particles on which Au nanoparticles were immobilized (QD/SiO2/Au particles), and the QD/SiO2/Au particles coated with silica (QD/SiO2/Au/SiO2 multi-layered particles).
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