| Budget Amount *help |
¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2014: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
|
|---|
| Outline of Final Research Achievements |
Oligomerization and spatial orientation is a highly effective strategy for control and extension of functions of biomaterials. In this study, we selected biomineralization as a bioreaction and the p53 tetramerization domain structure as a spatial control element. We evaluated the effect of precisely defining the spatial orientation, arrangement and valency of the biomineralization peptide on the produced nanostructures. The results clearly have demonstrated that oligomerization and spatial orientation of biomineralization peptides via the spatial control element can effectively control the formation, structures and functions of metal nanoparticles.
|
