Understanding the neural substrates of anxiety through mind-brain-body interactions: Integrative investigations from psychology, psychiatry and psychosomatic medicine
Project/Area Number |
24330210
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Experimental psychology
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Research Institution | Keio University |
Principal Investigator |
Umeda Satoshi 慶應義塾大学, 文学部, 教授 (90317272)
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Co-Investigator(Kenkyū-buntansha) |
MIMURA Masaru 慶應義塾大学, 医学部, 教授 (00190728)
MORIGUCHI Yoshiya 独立行政法人国立精神・神経医療研究センター, 精神保健研究所, 研究員 (40392477)
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Co-Investigator(Renkei-kenkyūsha) |
TERASAWA Yuri 慶應義塾大学, 文学部, 助教 (30585790)
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Project Period (FY) |
2012-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2014: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2013: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2012: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
|
Keywords | 不安 / 情動 / 内受容感覚 / 島皮質 / 自律神経障害 / 自律神経反応 / 脳機能画像 / 神経心理学 / 不安障害 / パニック障害 / 心身医学 |
Outline of Final Research Achievements |
Many recent studies have investigated the mechanisms of anxiety and panic symptoms, but causal factors of them remain unresolved. To understanding the neural substrates of anxiety, we focused on the mind-brain-body interactions from integrative perspectives including psychology, psychiatry and psychosomatic medicine. A series of experimental studies using MRI and EEG showed the importance of interoception, the involvement of the insular cortex, and that the dysfunction of this mechanism was observed in autonomic disorders.
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Report
(5 results)
Research Products
(42 results)
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[Journal Article] Fear conditioning induced by interpersonal conflicts in healthy individuals.2015
Author(s)
Tada, M., Uchida, H.,, Maeda, T., Konishi, M., Umeda, S., Terasawa, Y., Nakajima, S., Mimura, M., Miyazaki, T., & Takahashi, T.
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Journal Title
PLOS ONE
Volume: -
Issue: 5
Pages: e0125729-e0125729
DOI
Related Report
Peer Reviewed / Open Access
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[Presentation] Structural brain abnormalities in postural tachycardia syndrome: A VBM-DARTEL study.2015
Author(s)
Umeda, S., Harrison, N. A., Gray, M. A., Mathias, C. J., & Critchley, H. D.
Organizer
Neuroscience 2015
Place of Presentation
McCormick Place, Chicago, USA
Year and Date
2015-10-17
Related Report
Int'l Joint Research
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[Presentation] Insular lesion and attenuated sensitivity to the emotions of others2015
Author(s)
Terasawa, Y., Kurosaki, Y., Ibata, Y., Moriguchi, Y., & Umeda, S.
Organizer
Neuroscience 2015
Place of Presentation
McCormick Place, Chicago, USA
Year and Date
2015-10-17
Related Report
Int'l Joint Research
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[Presentation] Dissociation between interoceptive and emotional awareness in alexithymia.2014
Author(s)
Terasawa, Y., Moriguchi, Y., Kanayama, Y., Oba, K., Motomura, Y., Umeda, S., & Mishima, K.
Organizer
The 20th International Conference on Functional Mapping of the Human Brain.
Place of Presentation
ドイツ・ハンブルク
Year and Date
2014-06-08 – 2014-06-12
Related Report
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[Presentation] Neutral basis for autogenic training2013
Author(s)
H. Murakami, R. Katsunuma, K. Oba, Y. Terasawa, Y. Motomura, Y. Kanayama, K. Mishima, Y. Moriguchi, H. Matsuda
Organizer
The 71st Annual Meeting of the American Psychosomatic Society
Place of Presentation
Miami, FL, USA
Year and Date
2013-04-16
Related Report
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[Presentation] Neurofeedback-guided Mindfulness-based Attention Training with Real time FMRI2013
Author(s)
Y. Moriguchi, K. Oba, H. Murakami, R. Katsunuma, Y. Terasawa, Y. Kanayama, A. Hida, T. Hanakawa, K. Mishima
Organizer
Symposium 135: New Innovations in Neuroimaging of Autonomic Regulation in The 7 1st Annual Scientific Meeting of American Psychosomatic Society
Place of Presentation
Miami, FL, USA
Year and Date
2013-04-15
Related Report
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[Presentation] Application of real-time fMRI to cockroach phobia2013
Author(s)
Y. Moriguchi, K. Oba, H. Murakami, R. Katsunuma, Y. Terasawa, Y. Kanayama, A. Hida, T. Hanakawa, K. Mishima
Organizer
71st Annual Scientific Meeting, American Psychosomatic Society
Place of Presentation
Miami, FL, USA
Year and Date
2013-04-14
Related Report
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[Presentation] Bodily responses and the vulnerability to anxiety: An fMRI investigation2013
Author(s)
Umeda, S., Harrison, N. A., Gray, M. A., Mathias, C. J., & Critchley, H. D.
Organizer
The 6th annual meeting of the Social & Affective Neuroscience Society
Place of Presentation
San Francisco, USA
Related Report
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[Presentation] Association between emotional awareness and neural correlates of interoception2013
Author(s)
Terasawa, Y., Moriguchi, Y., Kanayama, Y., Oba, K., Motomura, Y., Umeda, S. & Mishima, K.
Organizer
The 53th Annual Meeting of the Society for Psychophysiological Research
Place of Presentation
Florence, Italy
Related Report
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