Construction of capsule-like coorporative molecular recognizing structures from saccharide-recognizing host molecules
| Project/Area Number |
24350066
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Functional materials chemistry
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| Research Institution | University of Toyama |
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Principal Investigator |
ABE Hajime 富山大学, 大学院医学薬学研究部(薬学), 准教授 (10324055)
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| Co-Investigator(Renkei-kenkyūsha) |
INOUYE Masahiko 富山大学, 大学院医学薬学研究部(薬学), 教授 (60211752)
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| Project Period (FY) |
2012-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2012: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Keywords | 糖認識 / ホスト分子 / カプセル型分子 / 集積構造 / フェノール / ピリジン / 繊維状構造 / トリフェノール / 水素結合 / 自己組織化 / 糖 / ホスト・ゲスト化学 / エチニルピリジン / 大環状化合物 / 薗頭反応 |
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| Outline of Final Research Achievements |
By applying artificial host molecules as parts, higher-order structures such as capsule-like and fibril structures have been built. Coordinative groups were introduced on the ortho positions of triphenolic host molecules, and the product tridentates were treated with a Pd(II) precursor to give M3L2-type capsule-like complex, which showed host ability. Macrocyclic host molecules consisted of 2,6- and 3,6-pyridylene rings were observed to self-associate by pi-stacking, and AFM images showed fibril structures. Tricationic derivative incorporated melamine with self-aggregate into cotton-like structure.
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Report
(5 results)
Research Products
(34 results)
