| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2014: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2013: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2012: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
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| Outline of Final Research Achievements |
We designed efficient molecular catalyst systems of CO2-addition reactions by utilization of CO2 adducts formed from molecular bases. For example, imidazolium-2-carboxylates derived from N-heterocyclic carbenes and CO2 can serve as effective organocatalysts for synthesis of five-membered cyclic urethanes from tertiary aziridines.
We also developed the carboxylative cyclization of propargylamines catalyzed by NHC-gold complexes to yield a series of cyclic urethanes. For the cyclization of allenylmethylamines, the related NHC-silver complexes were found to be advantageous. These catalytic cycles were also supported by synthetic studies on alkenylgold complexes as the model intermediates.
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