• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

UV resonance Raman investigation on detection of higher order structural changes of heme proteins and elucidation of functional regulation mechanism

Research Project

Project/Area Number 24350086
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Chemistry related to living body
Research InstitutionUniversity of Hyogo

Principal Investigator

KITAGAWA Teizo  兵庫県立大学, 生命理学研究科, 名誉教授 (40029955)

Co-Investigator(Kenkyū-buntansha) OGURA Takashi  兵庫県立大学, 生命理学研究科, 教授 (70183770)
NAGATOMO Shigenori  筑波大学, 数理物質科学研究科, 講師 (80373190)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000)
Fiscal Year 2014: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2013: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2012: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Keywords生物物理 / 蛋白質 / シグナル伝達 / 生体分子 / 分子認識 / 振動分光 / 共鳴ラマン散乱
Outline of Final Research Achievements

Cavity mutant human Hb, which lacks the Fe-His bond in either the α or β subunit but can bind four O2 molecules, was prepared. Its oxygen binding curve was determined, and higher order structural changes upon O2 binding were investigated with 1H NMR, V- and UV-resonance Raman, and nearUV CD spectra. Spectroscopic measurements revealed that the quaternary structure change did not occur upon ligand binding. The absence of Fe-His bond in α froze Hb in T while that of β raised the affinity of α. Resonance Raman spectra of NO sensor protein, mammalian sGC and its model protein, bacterial H-NOX, were investigated.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (102 results)

All 2015 2014 2013 2012

All Journal Article (45 results) (of which Peer Reviewed: 44 results,  Acknowledgement Compliant: 3 results,  Open Access: 4 results) Presentation (57 results) (of which Invited: 10 results)

  • [Journal Article] Infrared and Raman spectroscopic investigation of the reaction mechanism of cytochrome c oxidase2015

    • Author(s)
      Satoru Nakashima, Takashi Ogura, Teizo Kitagawa
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1847 Issue: 1 Pages: 86-97

    • DOI

      10.1016/j.bbabio.2014.08.002

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Formation and Characterization of a Reactive Chromium(V)-Oxo Complex: A Mechanistic Insight into Hydrogen-Atom Transfer Reactions2015

    • Author(s)
      H. Kotani, S. Kaida, T. Ishizuka, M. Sakaguchi, T. Ogura, Y. Shiota, K. Yoshizawa, T. Kojima
    • Journal Title

      Chemical Science

      Volume: 6 Issue: 2 Pages: 945-955

    • DOI

      10.1039/c4sc02285h

    • NAID

      120007130469

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Higdla is a oositive regulaator of cytochrome c oxidase2015

    • Author(s)
      T. Hayashi, Y. Asano, Y. Shintani, H. Aoyama, H. Kioka, O. Tsukamoto, M. Hikita, K. Shinzawa-Itoh, K. Takajuji, S. Higo, H. Kato, S. Yamazaki, K. Matsuoka, A. Nakano, H. Asanuma, M. Asakura, T. Minamino, Y. Goto, T. Ogura, M. Kitakaze, I. Komuro, Y. Sakata, T. Tsukihara, S. Yoshikawa, S. Takashima
    • Journal Title

      Proc. Nat. Acad. Sci. U.S.A.

      Volume: 112 Issue: 5 Pages: 1553-1558

    • DOI

      10.1073/pnas.1419767112

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Resonance Raman spectroscopy with chemical state selectivity on histidine and acetamide using synchrotro radiation2015

    • Author(s)
      M. Saito, F. D. Amico, G. Camisasca, F. Benchivonga, R. Cucini, A. Gossini, E. Principi, T. Ogura, and C. Masciovecchio
    • Journal Title

      Bu.. Chem. Soc. Jpn

      Volume: 88 Issue: 4 Pages: 591-596

    • DOI

      10.1246/bcsj.20140367

    • NAID

      130005064988

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Involvement of propionate side chians of the hee in circular dichroism of myoglobin: experimental and theoretical analyses2015

    • Author(s)
      M. Nagai, C. Kobayashi, Y. Nagai, K. Imai, N. Mizusawa, H. Sakurai, S. Neya, M. Kayanuma, M. Shoji and S. Nagatomo
    • Journal Title

      J. Phys. Chem. B

      Volume: 119 Pages: 1275-1287

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Picobiology revealed by vibrational spectroscopy2014

    • Author(s)
      Teizo Kitagawa
    • Journal Title

      Journal Spectroscopic Society of Japan

      Volume: 63 Pages: 49-61

    • NAID

      40020077942

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Highly Reactive Nonheme Iron(III)-Iodosylarene Complexes in Alkane Hydroxylation and Sulfoxidation Reactions2014

    • Author(s)
      S. Hong, B. Wang, M. S. Seo, Y. M. Lee, M. J. Kim, H. Kim, T. Ogura, R. Garcia-Serres, M. Clemancey, J. M. Latour, W. Nam
    • Journal Title

      Angewant Chemie Intl. Edi.

      Volume: 53 Issue: 25 Pages: 6388-6392

    • DOI

      10.1002/anie.201402537

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of damage-free crystal structure of an X-ray sensitive protein using an XFEL2014

    • Author(s)
      Hirata K, Shinzawa-Itoh K, Yano N, Takemura S, Kato K, Hatanaka M, Muramoto K, Kawahara T, Tsukihara T, Yamashita E, Tono K, Ueno G, Hikima T, Murakami H, Inubushi Y, Yabashi M, Ishikawa T, Yamamoto M, Ogura T, Sugimoto H, Shen J-R, Yoshikawa S, Ago H
    • Journal Title

      Nature Methods

      Volume: 11 Issue: 7 Pages: 734-736

    • DOI

      10.1038/nmeth.2962

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the electron density of the heme Fe atom o the Fe-Histidine coordination bond in deoxy myoglobin2014

    • Author(s)
      R. Nishimura, T. Shibata, H. Tai, I. Ishigami, S. Yanagisawa, T. Ogura, S. Neya, A. Suzuki, Y. Yamamoto
    • Journal Title

      Bull. Chem. Soc. Jpn.

      Volume: 87 Issue: 8 Pages: 905-911

    • DOI

      10.1246/bcsj.20130331

    • NAID

      130004153305

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Geometric control of nuclearity in copper(I)/dioxygen chemistry2014

    • Author(s)
      T. Abe, Y. Morimoto, T. Tano, K. Mieda, H. Sugimotok N. Fujieda, T. Ogura, and S. Itoh
    • Journal Title

      Inorganic Chemistry

      Volume: 53 Issue: 16 Pages: 8786-8794

    • DOI

      10.1021/ic501461n

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electronic control of ligand-binding preference of a myoglobin mutant2014

    • Author(s)
      R. Nishimura, D. Matsumoto, T. Shibata, S. Yanagisawa, T. Ogura, H. Tai, T. Matsuo, S. Hirota, S. Neya, A. Suzuki, Y. Yamamoto
    • Journal Title

      Inorganic Chemistry

      Volume: 53 Issue: 17 Pages: 9156-9165

    • DOI

      10.1021/ic5011924

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of ligand flexibility on the electronic structure of oxidized Ni(III)-phenoxide complexes2014

    • Author(s)
      M. Kawai, T. Yamaguchi, S. Masaoka, F. Tani, T. Kohzuma, L. Chiang, T. Storr, K. Mieda, T. Ogura, r. K. Szilagyi, and Y. Shimazaki
    • Journal Title

      Inorganic Chemistry

      Volume: 53 Issue: 19 Pages: 10195-10202

    • DOI

      10.1021/ic501181k

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of proton motive force on the structure and dynamics of bovine cytochrome c oxidase in phospholipid visicles2014

    • Author(s)
      T. Nomura, S. Yanagisawa, K. Shinzawa-Itoh, S. Yoshikawa, and T. Ogura
    • Journal Title

      Biochemistry

      Volume: 53 Issue: 40 Pages: 6382-6391

    • DOI

      10.1021/bi501022j

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interplay between phase transition of DPPC bilayer and photoisomerization of doped stilbene molecule2014

    • Author(s)
      K. Nakazawa, M.Hishida, S. Nagatoo, Y. Yamamura, and K. Saito
    • Journal Title

      Chemistry Letters

      Volume: 43 Pages: 1352-1354

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recentant nematic phase in 4-alkyl-4'-cyanobiphenyl(nCB) binary mixtures2014

    • Author(s)
      S. Fujimura, Y. Yamamura, M. Hishida, S. Nagatomo, and K. Saito
    • Journal Title

      Liquid Crystals

      Volume: 41 Pages: 927-932

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Copper complexes supported by an N2S-tridentate ligand as active site models of copper monooxygenases2014

    • Author(s)
      Shinobu Itoh, et al.
    • Journal Title

      Dalton Trans.

      Volume: 42 Issue: 12 Pages: 4871-4877

    • DOI

      10.1039/c3dt52952e

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of Carboxylate Donors in O-O Bond Scission of Peroxodiiron(III) to High-Spin Oxodiiron(IV) with a New Carboxylate-Containing Dinucleating Ligand2014

    • Author(s)
      M. Kodera, T. Tsuji, T. Yasunaga, Y. Kawahara, T. Hirano, Y. Hitomi, T. Nomura, T. Ogura, Y. Kobayashi, Sajith P. K., Y. Shiota, and K. Yoshizawa
    • Journal Title

      Chem. Sci.

      Volume: 5 Issue: 6 Pages: 2282-2292

    • DOI

      10.1039/c3sc51541a

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Effective Pumping Proton Collection Facilitated by a Copper Site (CuB) of Bovine Heart Cytochrome c Oxidase, Revealed by a Newly Developed Time-resolved Infrared System2013

    • Author(s)
      Minoru Kubo, Satoru Nakashima, Satoru Yamaguchi, Takashi Ogura, Masao Mochizuki, Jiyoung Kang, Masaru Tateno, Kyoko Shinzawa-Itoh, Koji Kato and Shinya Yoshikawa
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Issue: 42 Pages: 30259-30269

    • DOI

      10.1074/jbc.m113.473983

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Redox Properties of Mononuclear Copper(II)-Superoxide Complex2013

    • Author(s)
      Shinobu Itoh
    • Journal Title

      Inorg. Chem.

      Volume: 52 Issue: 18 Pages: 10431-10437

    • DOI

      10.1021/ic401261z

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Near-UV Circular dichroism and UV resonance Raman spectra of tryptophan residues as a structural marker of proteins.2013

    • Author(s)
      Biswajit Pal, Katsuhiro Tanaka, Shigeo Takenaka, and Teizo Kitagawa
    • Journal Title

      J. Porphyrins Phthalocyanines

      Volume: 17 Issue: 03 Pages: 240-246

    • DOI

      10.1142/s1088424613500375

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Near-UV Circular dichroism and UV resonance Raman spectra of tryptophan residues as a structural marker of proteins.2013

    • Author(s)
      Shigenori Nagatomo, Masako Nagai, Takashi Ogura, and Teizo Kitagawa
    • Journal Title

      J. Physical Chemistry B

      Volume: 117 Issue: 32 Pages: 9343-9363

    • DOI

      10.1021/jp404685x

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mononuclear manganese-peroxo and bis(μ-oxo)dimanganese complexes bearing a common N-methylated macrocyclic ligand2013

    • Author(s)
      Hyeona Kang, Jaeheung Cho, Kyung-Bin Cho, Takashi Nomura, Takashi Ogura, Wonwoo Nam
    • Journal Title

      Chemistry

      Volume: 19 Issue: 42 Pages: 14119-14125

    • DOI

      10.1002/chem.201301641

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electronic Control of Discrimination between O2 and CO in Myoglobin Lacking the Distal Histidine Residue2013

    • Author(s)
      R. Nishimura, T. Shibata, I. Ishigami, T. Ogura, H. Tai, S. Nagao, T. Matsuo, S Hirota, O. Shoji, Y. Watanabe, K. Imai, S. Neya, A. Suzuki, Y. Yamamoto
    • Journal Title

      Inorg. Chem.

      Volume: 53 Issue: 2 Pages: 1091-1099

    • DOI

      10.1021/ic402625s

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxo-sulfido- and oxo-selenido-molybdenum(VI) complexes possessing dithiolene ligand related to the active sites of hydroxylases of molybdoenzymes: Low temperature preparation and characterisation2013

    • Author(s)
      Shinobu Itoh, et al.
    • Journal Title

      Chem. Commun.

      Volume: 49 Issue: 39 Pages: 4358-4360

    • DOI

      10.1039/c2cc35345h

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A new series of bis(ene-1,2-dithiolato)tungsten(IV), -(V), -(VI) complexes as reaction centre models of tungsten enzymes: preparation, crystal structures and spectroscopic properties2013

    • Author(s)
      Shinobu Itoh, et al.
    • Journal Title

      Dalton Trans.

      Volume: 42 Issue: 9 Pages: 3059-3070

    • DOI

      10.1039/c2dt32179c

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Resonance Raman spectral properties of FMN of bovine heart NADH:ubiquinoneoxidoreductase suggesting a mechanism for the prevention of spontaneous production of reactive oxygen species2013

    • Author(s)
      Hikita M, Shinzawa-Itoh K, Moriyama M, Ogura T, Kihira K, Yoshikawa S
    • Journal Title

      Biochemistry

      Volume: 52(1) Issue: 1 Pages: 98-104

    • DOI

      10.1021/bi3011972

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of Hydrogen-Bonded Oligomers in Associating Liquid by 'H NMR : 1-Phenyl-1-cyclohexanol2013

    • Author(s)
      Shigenori Nagatomo, Megumi Nobuhira, Yasuhisa Yamamura, Masato Sumita, and Kazuya Saito
    • Journal Title

      Bull. Chem. Soc. Jpn.

      Volume: (印刷中) Issue: 5 Pages: 569-576

    • DOI

      10.1246/bcsj.20120322

    • NAID

      10031167848

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radical localization in a series of symmetric Ni^<II> complexes with oxidized salen ligands2013

    • Author(s)
      Linus Chiang, Amelie Kochem, Olivier Jarjayes, Tim J. Dunn, Herve Vezin, Miyuki Sakaguchi, Takashi Ogura, Maylis Orio, Yuichi Shimazaki, Fabrice Thomas and Tim Storr
    • Journal Title

      Chemistry-A European Journal

      Volume: 18 Issue: 44 Pages: 14117-14127

    • DOI

      10.1002/chem.201201410

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction of dimeric horse cytochrome c with cyanide ion2013

    • Author(s)
      Ari Dwi Nugraheni, Satoshi Nagao, Sachiko Yanagisawa, Takashi Ogura and Shun Hirota
    • Journal Title

      J Biol Inorg Chem

      Volume: 18 Issue: 3 Pages: 383-390

    • DOI

      10.1007/s00775-013-0982-8

    • NAID

      120005716871

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between the Electron Density of the Heme Fe Atom and the Vibrational Frequencies of the Fe-Bound Carbon Monoxide in Myoglobin2013

    • Author(s)
      R. Nishimura, T. Shibata, H. Tai, I. Ishigami, T. Ogura, S. Nagao, T. Matsuo, S. Hirota, K. Imai, S. Neya, A. Suzuki, and Y, Yamamoto
    • Journal Title

      Inorg. Chem.

      Volume: 52 Issue: 6 Pages: 3349-3355

    • DOI

      10.1021/ic3028447

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Resonance Raman Study on Indoleamine 2,3-Dioxygenase: Control of Reactivity by Substrate-Binding2013

    • Author(s)
      Sachiko Yanagisawa, Masayuki Hara, Hiroshi Sugimoto, Yoshitsugu Shiro and Takashi Ogura
    • Journal Title

      Chem. Phys.

      Volume: in press Pages: 178-183

    • DOI

      10.1016/j.chemphys.2013.02.032

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2) : Conversion from His119/Cys170 coordination to His119/His171 coordination2012

    • Author(s)
      Takeshi Uchida, Ikuko Sagami, Toru Shimizu, Koichiro Ishimori, and Teizo Kitagawa
    • Journal Title

      J. Inorg. Biochem.

      Volume: 108 Pages: 188-195

    • DOI

      10.1016/j.jinorgbio.2011.12.005

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Near-UV circular dichroism and UV resonance Raman spectra of individual trytophan residues in human hemoglobin and their changes upon the quaternary structure transition2012

    • Author(s)
      Masako Nagai, Shigenori Nagatomo, Yukifumi Nagai, Kenichi Ohkubo, Kiyohiro Imai, and Teizo Kitagawa
    • Journal Title

      Biochemistry

      Volume: 51 Issue: 30 Pages: 5932-5941

    • DOI

      10.1021/bi300347x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An intermediate conformational state during ligand binding to cytochrome c oxidase detected by time-resolved resonance Raman analyses of heme peripheral groups2012

    • Author(s)
      Izumi Ishigami, Takeshi Nishigaki, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, Satoru Nakashima and Takashi Ogura
    • Journal Title

      Chem. Lett.

      Volume: 2 Issue: 2 Pages: 178-180

    • DOI

      10.1246/cl.2012.178

    • NAID

      130004426495

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Site-specific protein dynamics in communication pathway from sensor to signaling domain of oxygen sensor protein, HemAT-Bs : time-resolved ultraviolet resonance Raman study2012

    • Author(s)
      S. El-Mashtoly, M. Kubo, Y. Gu, H. Sawai, S. Nakashima, T. Ogura, S. Aono, T. Kitagawa
    • Journal Title

      J. Biol. Chem

      Volume: 287 Issue: 24 Pages: 19973-19984

    • DOI

      10.1074/jbc.m112.357855

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Copper(I)-Dioxygen Reactivity in a Sterically Demanding Tripodal Tetradentate tren Ligand. Formation and Reactivity of a Mononuclear Copper(II) End-on Superoxo Complex2012

    • Author(s)
      Shinobu Itoh, et al.
    • Journal Title

      Eur. J. Inorg. Chem.

      Volume: 2012 Issue: 29 Pages: 4574-4578

    • DOI

      10.1002/ejic.201200177

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-innocent ligand behaviour of a bimetallic Cu complex employing a bridging catecholate2012

    • Author(s)
      Tim J. Dunn, Linus Chiang, Caterina F. Ramogida, Mike I. Webb, Didier Savard, Miyuki Sakaguchi, Takashi Ogura, Yuichi Shimazaki and Tim Storr
    • Journal Title

      Dalton Transactions

      Volume: 41 Issue: 26 Pages: 7905-7914

    • DOI

      10.1039/c2dt30444a

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] [Fe^<IV>=O(TBC)(CH3CN)]^<2+> : Comparative Reactivity of Iron(IV)-Oxo Species with Constrained Equatorial Cyclam Ligation2012

    • Author(s)
      Samuel A. Wilson, Junying Chen, Seungwoo Hong, Yong-Min Lee, Martin Clemancey, Ricardo Garcia-Serres, Takashi Nomura, Takashi Ogura, Jean-Marc Latour, Britt Hedman, Keith O. Hodgson, Wonwoo Nam, and Edward I. Solomon
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 134 Issue: 28 Pages: 11791-11806

    • DOI

      10.1021/ja3046298

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tuning the geometries of a de novo blue copper protein by axial interactions2012

    • Author(s)
      Daigo Shiga, Yusuke Hamano, Misato Kamei, Yasuhiro Funahashi, Hideki Masuda, Miyuki Sakaguchi, Takashi Ogura and Toshiki Tanaka
    • Journal Title

      Journal of Biological Inorganic Chemistry

      Volume: 17 Issue: 7 Pages: 1025-1031

    • DOI

      10.1007/s00775-012-0916-x

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the Axial Ligand on the Reactivity of the Oxoiron(IV) Porphyrin p-Cation Radical Complex: Higher Stabilization of the Product State Relative to the Reactant State2012

    • Author(s)
      A. Takahashi, D. Yamaki, K. Ikemuma, T. Kurahashi, T. Ogura, M. Hada, and H. Fujii
    • Journal Title

      Inorg. Chem.

      Volume: 51(13) Issue: 13 Pages: 7296-7305

    • DOI

      10.1021/ic3006597

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reversible O-O Bond Scission of Peroxodiiron(III) to High-Spin Oxodiiron(IV) in Dioxygen Activation of a Diiron Center with a Bis-tpa Dinucleating Ligand as a Soluble Methane Monooxygenase Model2012

    • Author(s)
      Masahito Kodera, Yuka Kawahara, Yutaka Hitomi, Takashi Nomura, Takashi Ogura, and Yoshio Kobayashi
    • Journal Title

      J. Am. Chem. Soc.

      Volume: 134 Issue: 32 Pages: 13236-13239

    • DOI

      10.1021/ja306089q

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanistic insights into catalytic oxidations of organic compounds by ruthenium (IV)-oxo complexes with pyridylamine ligands2012

    • Author(s)
      Shingo Ohzu, Tomoya Ishizuka, Yuichiro Hirai, Hua Jiang, Miyuki Sakaguchi, Takashi Ogura, Shunichi Fukuzumi, Takahiko Koj ima
    • Journal Title

      Chemical Science

      Volume: 3 Issue: 12 Pages: 3421-3431

    • DOI

      10.1039/c2sc21195e

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chromium(IV)-peroxo complex formation and its nitric oxide dioxygenase reactivity2012

    • Author(s)
      Yokoyama, A., Han, J. E., Cho, J., Kubo, M., Ogura, T., Siegler, M. A., Karlin, K. D., Nam, W
    • Journal Title

      J. Am. Chem. Soc

      Volume: Vol. 134 Issue: 37 Pages: 15269-15272

    • DOI

      10.1021/ja307384e

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis, Characterization, and Reactivity of Hypochlorito-Iron(III) Porphyrin Complexe2012

    • Author(s)
      Zhiqi Cong, Sachiko Yanagisawa, Takuya Kurahashi, Takashi Ogura, Satoru Nakashima, and Hiroshi Fujii
    • Journal Title

      J. Am. Chem. Soc

      Volume: 134 Issue: 51 Pages: 20617-20620

    • DOI

      10.1021/ja3108774

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Resonance Raman Application in Investigations of Cytochrome c Oxidase2012

    • Author(s)
      Takashi Ogura
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1817 Issue: 4 Pages: 575-578

    • DOI

      10.1016/j.bbabio.2011.11.016

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 金属中心-タンパク質間の情報伝達ダイナミクス:赤外分光法による検出2015

    • Author(s)
      小倉尚志
    • Organizer
      分子研研究会「生物無機化学の最先端の今後の展望」
    • Place of Presentation
      岡崎コンファレンスセンター(愛知県岡崎市)
    • Year and Date
      2015-01-06 – 2015-01-07
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Different roles of the fe-His bonds of the a and b subunits toward the quaternary structure change of human hemoglobin; Oxygen binding properties, resonance Raman, 1H NMR, and near-UV CD studies of cavity mutants2014

    • Author(s)
      Teizo Kitagawa
    • Organizer
      7th Asian Biological Inorganic Chemistry Conference
    • Place of Presentation
      Gold Coast, Australia
    • Year and Date
      2014-11-30 – 2014-12-05
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Vibrational spectroscopic investigation of molecular mechanisms of aerobic respiration2014

    • Author(s)
      T. Ogura
    • Organizer
      Advances in Live Single-cell Thermal Imaging and Manipulation
    • Place of Presentation
      沖縄科学技術大学院大学シーサイドハウス(沖縄県国頭郡恩納村)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Function and structure of mutant hemoglobins with proximal histidine replaced by glycine in either a or b subunits2014

    • Author(s)
      S. Nagatomo, Y. Nagai, Y. Aki, H. Sakurai, N. Maruyama, K. Imai, N. Mizusawa, T. Ogura, T. Kitagawa and m. Nagai
    • Organizer
      日本生物物理学会第52回年会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Resonance Raman investigation of structural changes of heme of sGC caused by substrate, ligand and effectors2014

    • Author(s)
      Teizo Kitagawa
    • Organizer
      8th International Conference on Porphyrins and Phthalocyanines
    • Place of Presentation
      istanbul, Turkey
    • Year and Date
      2014-06-22 – 2014-06-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Cooperative structural dynamics of proton pumping elements in cytochrome c oxidase as studied by onnovative infrared spectroscopy2014

    • Author(s)
      T. Ogura, S. Nakashima, M. Kubo, S.Yamaguchi, M. Mochizuki, K. Shinzawa-itoh, S. Yoshikawa
    • Organizer
      8th International Conference on Porphyrins and Phthalocyanines (ICPP-8)
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2014-06-22 – 2014-06-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Visible and UV resonance Raman study on indoleamine 2,3-dioxygenase2014

    • Author(s)
      S. Yanagasawa, M. Hara, K. E. Kayama, H. Sugimoto, Y. Shiro, and T. Ogura
    • Organizer
      8th International Conference on Porphyrins and Phthalocyanines (ICPP-8)
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2014-06-22 – 2014-06-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] チトクロムc酸化酵素の酸化還元反応の時間分解赤外吸収測定を目的とした酸素肺フローシステムの開発2014

    • Author(s)
      西口達人, 引田理英, 新澤-伊藤恭子, 吉川信也, 中島 聡, 小倉尚志
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 時間分解振動分光法によるチトクローム酸化酵素の反応初期過程2014

    • Author(s)
      中島 聡, 久保 稔, 石上 泉, 新澤-伊藤恭子, 吉川信也, 小倉尚志
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Peroxide-reactivity of copper complexes supported by tridentate ligands having cyclic-diamine frameworks2014

    • Author(s)
      Tsukasa Abe, Takashi Ogura, Yuma Morimoto, Hideki Sugimoto, Nobutaka Fujieda, and Shinobu Itoh
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] ヘム鉄の電子密度の変化がデオキシミオグロビンのFe-His配位結合に及ぼす影響2014

    • Author(s)
      西村 龍, 柴田友和, 太 虎林, 石上 泉, 柳澤幸子, 小倉尚志, 根矢三郎, 鈴木秋弘, 山本泰彦
    • Organizer
      日本化学会第94春季年会
    • Place of Presentation
      名古屋大学 東山キャンパス(愛知県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Resonance Raman Study on Cytochrome c Oxidase Reconstituted in the Phospholipids Vesicles2013

    • Author(s)
      Takashi Nomura, Sachiko Yanagisawa, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, and Takashi Ogura
    • Organizer
      The 4th Georgian Bay International Conference on Bioinorganic Chemistry (CanBIC-4)
    • Place of Presentation
      Parry Sound, Canada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Interaction Between Heme and Heme-Cu Binuclear center in Cytochrome c oxidase2013

    • Author(s)
      Miyuki Sakaguchi, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, and Takashi Ogura
    • Organizer
      The 4th Georgian Bay International Conference on Bioinorganic Chemistry (CanBIC-4)
    • Place of Presentation
      Parry Sound, Canada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Detection of tryptophan as bound substrate in indoleamine 2,3-dioxygenase2013

    • Author(s)
      Sachiko Yanagisawa, Masayuki Hara, Hiroshi Sugimoto, Yoshitsugu Shiro, and Takashi Ogura
    • Organizer
      The 4th Georgian Bay International Conference on Bioinorganic Chemistry (CanBIC-4)
    • Place of Presentation
      Parry Sound, Canada
    • Related Report
      2013 Annual Research Report
  • [Presentation] Identification of functionally important conformational changes in cytochrome c oxidase2013

    • Author(s)
      Takashi Ogura
    • Organizer
      The 4th Georgian Bay International Conference on Bioinorganic Chemistry (CanBIC-4)(招待講演)
    • Place of Presentation
      Parry Sound, Canada
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ドメインスワップしたシトクロムc多量体の形成および安定性に影響を及ぼす因子2013

    • Author(s)
      廣田 俊, Ari Dwi Nugraheni, 山城信裕, 安藤勇輝, 長尾 聡, Zhonghua Wang, 柳澤幸子, 小倉尚志
    • Organizer
      第40回生体分子科学討論会
    • Place of Presentation
      大阪大学吹田キャンパス(大阪府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 基質結合型インドールアミン2,3 ジオキシゲナーゼの基質の検出-紫外共鳴ラマン分光法2013

    • Author(s)
      柳澤幸子, 原 雅行, 杉本 宏, 城 宜嗣, 小倉尚志
    • Organizer
      第40回生体分子科学討論会
    • Place of Presentation
      大阪大学吹田キャンパス(大阪府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 休止酸化型チトクロムc酸化酵素の酸化還元部位の化学構造2013

    • Author(s)
      坂口美幸, 新澤-伊藤恭子, 吉川信也, 小倉尚志
    • Organizer
      感応性化学種が拓く新物質科学第2回公開シンポジウム
    • Place of Presentation
      九州大学医学部百年記念講堂(福岡県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 酵素反応中に見られる感応性化学種の振動分光法による補足と精密構造解析2013

    • Author(s)
      小倉尚志
    • Organizer
      感応性化学種が拓く新物質科学第2回公開シンポジウム
    • Place of Presentation
      九州大学医学部百年記念講堂(福岡県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] チトクロムc酸化酵素の高効率プロトンポンプを可能にするタンパク質構造ダイナミクス: 振動分光法2013

    • Author(s)
      小倉尚志
    • Organizer
      第13回日本蛋白質科学会年会
    • Place of Presentation
      とりぎん文化会館(鳥取県)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Real time observation of water-channel closure controlled by CuB in bovine cytochrome c oxidase using a novel high-sensitivity infrared system2013

    • Author(s)
      Minoru Kubo, Satoru Nakashima, Satoru Yamaguchi, Takashi Ogura, Masao Mochizuki, Jiyoung Kang, Masaru Tateno, Kyoko Shinzawa-Itoh, Koji Kato, and Shinya Yoshikawa
    • Organizer
      International Conference on BioInorganic Chemistry ICBIC-16
    • Place of Presentation
      Grenoble, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] Mechanism for ligand discrimination in myoglobin2013

    • Author(s)
      Yasuhiko Yamamoto, Ryu Nishimura, Tomokazu Shibata, Hulin Tai, Izumi Ishigami, Takashi Ogura, Satoshi Nagao, Takashi Matsuo, Shun Hirota, Kiyohiro Imai, Saburo Neya, and Akihiro Suzuki
    • Organizer
      International Conference on BioInorganic Chemistry ICBIC-16
    • Place of Presentation
      Grenoble, France
    • Related Report
      2013 Annual Research Report
  • [Presentation] High-resolution femtosecond crystallography at SACLA, a challenge of reducing the X-ray radiation damage on super molecular assemblies2013

    • Author(s)
      Hideo Ago, Kunio Hirata, Go Ueno, Hironori Murakami, Takehiko Tosha, Tamao Hisano, Minoru Kubo, Hiroshi Sugimoto, Yoshitsugu Shiro, Masaki Yamamoto, Eiki Yamashita, Jian-Ren Shen, Kyoko Shinzawa-Ito, Koji Kato, Miki Hatanaka, Shuhei Takemura, Naomine Yano, Takashi Ogura, Shinya Yoshikawa, and Tomitake Tsukihara
    • Organizer
      11th International Conference on Biology and Synchrotron Radiation (BSR)
    • Place of Presentation
      Grand Elysee Hotel Hamburg, Germany
    • Related Report
      2013 Annual Research Report
  • [Presentation] 完全酸化型チトクロム c 酸化酵素の酸化還元活性金属中心とアザイドの相互作用の分光学的研究2013

    • Author(s)
      Masahide Hikita, Akima Yamamoto, Tomoko Maeda, Kyoko Shinzawa-Itoh, Takashi Ogura, and Shinya Yoshikawa
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 発  表  標  題 チトクロムc 酸化酵素の酸素還元反応における赤外吸収測定を目的とした酸素肺フローシステムの開発2013

    • Author(s)
      Tatsuhito Nishiguchi, Masahide Hikita, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, Satoru Nakashima, and Takashi Ogura
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] インドールアミン2,3 ジオキシゲナーゼの基質トリプトファンの検出-紫外共鳴ラマン分光法2013

    • Author(s)
      achiko Yanagisawa, Masayuki Hara, Hiroshi Sugimoto, Yoshitsugu Shiro, and Takashi Oguara
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] タンパク質中のトリプトファン残基の近紫外円二色性と紫外共鳴ラマンスペクトルの特性2013

    • Author(s)
      higenori Nagatomo, Masako Nagai, Takashi Ogura, and Teizo Kitagawa
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] Interaction Between Heme and Heme-Cu Binuclear Center in Cytochrome c Oxidase2013

    • Author(s)
      Miyuki Sakaguchi, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, and Takashi Ogura
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      京都国際会館(京都府)
    • Related Report
      2013 Annual Research Report
  • [Presentation] 生体高分子の機能制御におけるゆらぎの役割2013

    • Author(s)
      長友重紀
    • Organizer
      つくばソフトマター研究会2013
    • Place of Presentation
      筑波大学(茨城県)
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] ヘモグロビンの機能制御における四次構造変化、α鎖,β鎖の役割:共鳴ラマン分光による研究2013

    • Author(s)
      長友重紀
    • Organizer
      第26回生物無機化学夏季セミナー(生物無機化学研究会)
    • Place of Presentation
      茨城県、阿字ケ浦クラブ
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Thermodynamic Study of Cyclic Oligomers via Hydrogen Bonds in Organic Liquids2013

    • Author(s)
      higenori Nagatomo, Yasuhisa Yamamura, Kazuya Saito
    • Organizer
      The Fifth International Symposium on the New Frontiers of Thermal Studies of Materials.
    • Place of Presentation
      Yokohama Media and Communications Center(神奈川県)
    • Related Report
      2013 Annual Research Report
  • [Presentation] チトクロムc酸化酵素によるプロトンポンプ反応の研究:時間分解赤外および共鳴ラマン分光法2013

    • Author(s)
      小倉尚志
    • Organizer
      分子研研究会「生物物質科学の展望」
    • Place of Presentation
      分子研明大寺地区(愛知県)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 生体配位化学における高解像度の虫眼鏡:振動分光法2013

    • Author(s)
      小倉尚志
    • Organizer
      分子研研究会「生体配位化学の最前線と展望」
    • Place of Presentation
      分子研明大寺地区(愛知県)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ミトコンドリア呼吸鎖電子伝達複合体Iに含まれるFMNの共鳴ラマンスペクトル2013

    • Author(s)
      引田理英、新澤伊藤恭子、森山昌和、小倉尚志、木平清人、吉川信也
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学びわこ・くさつキャンパス(滋賀県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] インドールアミン2, 3-ジオキシゲナーゼの共鳴ラマンスペクトル:基質結合による反応性の調節2013

    • Author(s)
      柳澤幸子、原 雅之、杉本 宏、城宜嗣、小倉尚志
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学びわこ・くさつキャンパス(滋賀県
    • Related Report
      2012 Annual Research Report
  • [Presentation] カルボン酸含有二核化配位子(BPG2E)を用いたパーオキソ二核鉄(III)錯体のO-O結合の開裂と基質酸化活性2013

    • Author(s)
      平野智也、河原由佳、人見穣、小寺政人、小林義男、野村高志、小倉尚志
    • Organizer
      日本化学会第93春季年会
    • Place of Presentation
      立命館大学びわこ・くさつキャンパス(滋賀県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Molecular Science of the Proteins in Organelles, Physiological Molecular Science of Membrane Proteins2012

    • Author(s)
      Takashi Ogura
    • Organizer
      分子高次系機能解明のための分子科学成果公開シンポジウム
    • Place of Presentation
      東京工業大学すずかけ台キャンパス(東京都)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒト成人ヘモグロビンへのベザフィブラートの結合による酸素親和性低下に関連した三次構造変化の解明2012

    • Author(s)
      長友重紀,濱田洋実,吉川裕之,斎藤一弥
    • Organizer
      第39回生体分子科学討論会
    • Place of Presentation
      東北大学片平さくらホール(宮城県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] トリプトファンの近紫外円二色性及び紫外共鳴ラマンに基づくヘモグロビンの四次構造変化の解明2012

    • Author(s)
      長井雅子,長友重紀,長井幸史,大久保賢一,今井清博,北川禎三
    • Organizer
      第39回生体分子科学討論会
    • Place of Presentation
      東北大学片平さくらホール(宮城県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 共鳴ラマン分光法によるインドールアミン2,3ジオキシゲナーゼの反応機構の研究2012

    • Author(s)
      柳澤幸子,原雅行,杉本宏,城宜嗣,小倉尚志
    • Organizer
      第39回生体分子科学討論会
    • Place of Presentation
      東北大学片平さくらホール(宮城県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Structural features in Functions of Heme Proteins Revealed by Resonance Raman Spectroscopy2012

    • Author(s)
      Teizo Kitagawa
    • Organizer
      国際プルフィリン・フタロシャニン学会
    • Place of Presentation
      Jeju (Korea)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cooperative Dynamics of the Two Hemes in Cytochrome c Oxidase upon Ligand Binding Identified by Time-Resolved Resonance Raman Spectroscopy2012

    • Author(s)
      Takashi Ogura, Izumi Ishigami, Takeshi Nishigaki, Satoru Nakashima, Kyoko Shinzawa-Itoha, and Shinya Yoshikawa
    • Organizer
      The 7th International Conference on Porphyrins and Phthalocyanines
    • Place of Presentation
      Jeju (Korea)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dioxygenation reaction of indoleamine 2,3-dioxygenase as studied by resonance Raman spectroscopy2012

    • Author(s)
      Sachiko Yanagisawa, Masayuki Hara, Hiroshi Sugimoto, Yoshitsugu Shiro, and Takashi Ogura
    • Organizer
      The 7th International Conference on Porphyrins and Phthalocyanines
    • Place of Presentation
      Jeju (Korea)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Proton Pump Mechanism of Cytochrome c Oxidase Elucidated by Highly Sensitive Time-Resolved IR Spectroscopy2012

    • Author(s)
      Satoru Nakashima, Minoru Kubo, Satoru Yamaguchi, Takashi Ogura, Masao Mochizukia, Kyoko Shinzawa-Itoh, and Shinya Yoshikawa
    • Organizer
      The 7th International Conference on Porphyrins and Phthalocyanines
    • Place of Presentation
      Jeju (Korea)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Protein Dynamics of Cytochrome c Oxidase Studied by Time-Resolved Resonance Raman and Infrared Spectroscopy : Coupling between 0_2 Reduction and H^+-Pumping2012

    • Author(s)
      Takashi Ogura
    • Organizer
      国際ラマン分光学会
    • Place of Presentation
      Bangalore (India)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of Heme Rotation around the Heme Normal by 90 °on Resonance Raman Spectra of Heme Proteins : Observation for Heme Oxygenase2012

    • Author(s)
      Sachiko Yanagisawa, Hiroshi Fujii, Saburo Neya, Takashi Ogura, and Teizo Kitagawa
    • Organizer
      国際ラマン分光学会
    • Place of Presentation
      Bangalore (India)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Essence in oxygen affinity regulation of human adult hemoglobin : Change of Fe-His bond length by quaternary or tertiary structure change2012

    • Author(s)
      Shigenori Nagatomo, Yasuhisa Yamamura, and Kazuya Saito
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Substitution effects of Gly for the proximal His of α subunits on the structure and oxygen binding function of human hemoglobin2012

    • Author(s)
      Yayoi Aki, Yukifumi Nagai, Kiyohiro Imai, Shigenori Nagatomo, Takashi Ogura, Teizo Kitagawa, and Masako Nagai
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] An Intermediate Conformation of Cytochrome Oxidase in the Ligand-Free State Identified by Time-Resolved Resonance Raman Spectroscopy2012

    • Author(s)
      Izumi Ishigami, Takeshi Nishigaki, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, Satoru Nakashima, and Takashi Ogura
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] The assignment of the resonance Raman bands of heme a peripheral substituents in cytochrome c oxidase2012

    • Author(s)
      Miyuki Sakaguchi, Yukie Katayama, Hiroshi Fujii, Hideo Shimada, and Takashi Ogura
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Ultraviolet Resonance Raman Study on Indoleamine 2, 3-Dioxygenase2012

    • Author(s)
      Masayuki Hara, Sachiko Yanagisawa, Hiroshi Sugimoto, Yoshitsugu Shiro, and Takashi Ogura
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of Heme Rotation around the Heme Normal by 90°on Resonance Raman Spectra of Heme Proteins; Observation for Heme Oxygenase2012

    • Author(s)
      Sachiko Yanagisawa, Hiroshi Fujii, Saburo Neya, Takashi Ogura, and Teizo Kitagawa
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Time-Resolved IR Analyses of Proteins Using a Novel Pulse Flow System Synchronized with Pump/Probe Lasers2012

    • Author(s)
      Minoru Kubo, Satoru Nakashima, Masao Mochizuki, Kyoko Shinzawa-Itoh, Shinya Yoshikawa, Takashi Ogura, and Teizo Kitagawa
    • Organizer
      The 50th Annual Meeting of the Biophysical Society of Japan
    • Place of Presentation
      Nagoya University (Aichi)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Structural Mechanism of Target Molecule Recognition by Gas Sensor Heme Proteins2012

    • Author(s)
      Teizo. Kitagawa
    • Organizer
      アジア生物無機化学会
    • Place of Presentation
      香港(中国)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 巨大タンパク質内での反応を観る:時間分解赤外および共鳴ラマン分光法2012

    • Author(s)
      小倉尚志
    • Organizer
      第1回分光イノベーションシンポジウム
    • Place of Presentation
      東京工業大学・百年記念館(東京都)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Relation among Fe-His bond, fluctuations of helices and oxygen affinity of hemoglobin in T-state and R-state2012

    • Author(s)
      Shigenori Nagatomo, Yukiko Ozeki, Yasuhisa Yamamura, and Kazuya Saito
    • Organizer
      Molecular Science of Fluctuations toward Biological Functions, 6th International Symposium
    • Place of Presentation
      Kyoto University (Kyoto)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ヒトヘモグロビンの酸素結合機能における近位ヒスチジンの役割2012

    • Author(s)
      丸山夏未,安芸弥生,長井幸史,今井清博,長友重紀,小倉尚志,北川禎三,長井雅子
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場・マリンメッセ福岡(福岡県)
    • Related Report
      2012 Annual Research Report

URL: 

Published: 2012-04-24   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi