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Development of a mouse MRI using a superconducting bulk magnet

Research Project

Project/Area Number 24360034
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied physics, general
Research InstitutionUniversity of Tsukuba

Principal Investigator

KOSE Katsumi  筑波大学, 数理物質系, 教授 (60186690)

Co-Investigator(Kenkyū-buntansha) NAKAMURA Takashi  理化学研究所, 分子構造解析ユニット, 専任技師 (60321791)
TERADA Yasuhiko  筑波大学, 数理物質系, 助教 (20400640)
Research Collaborator TAMADA Daiki  
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
KeywordsMRI / 高温超伝導 / 超伝導磁石 / バルク磁石
Outline of Final Research Achievements

We developed a magnetic resonance (MR) microscope using a high critical-temperature superconducting bulk magnet. The bulk magnet comprises six annular bulk superconductors (two end bulk magnets : 60 mm OD, 28 mm ID, and 23 mm height, four inner bulk magnets : 60 mm OD, 36 mm ID, and 18.5 mm height) made of c-axis oriented single-domain EuBa2Cu3Oy crystals. The magnet was energized using a superconducting NMR magnet for high-resolution NMR spectroscopy operating at 4.7 T. The trapped magnetic field was homogenized using a single-layer shim-coil developed in our group. The inhomogeneity of the trapped magnetic field measured with MR imaging was 15.4 ppm (peak-to-peak) in the 8.4 mm diameter and 10 mm long cylindrical region. Three-dimensional MR images of a chemically-fixed mouse fetus acquired with 50 micrometer cube voxels demonstrated the usefulness of our system.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (13 results)

All 2014 2013

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (10 results)

  • [Journal Article] Two-dimensional Compressed Sensing using the Cross-sampling Approach for Low-field MRI Systems2014

    • Author(s)
      Daiki Tamada, Katsumi Kose
    • Journal Title

      IEEE Transactions on Medical Imaging

      Volume: 33 Issue: 9 Pages: 1905-1912

    • DOI

      10.1109/tmi.2014.2326864

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Coupled circuit numerical analysis of eddy currents in an open MRI system2014

    • Author(s)
      Md. Shahadat Hossain Akram, Yasuhiko Terada, Ishi Keiichiro, Katsumi Kose
    • Journal Title

      J Magn Reson

      Volume: 245 Pages: 1-11

    • DOI

      10.1016/j.jmr.2014.05.001

    • NAID

      120007136616

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Experimental evaluation of the magnetization process in a high Tc bulk superconducting magnet using magnetic resonance imaging.2013

    • Author(s)
      Daiki Tamada, Takashi Nakamura, Yoshitaka Itoh, Katsumi Kose
    • Journal Title

      Physica C

      Volume: 492 Pages: 174-177

    • NAID

      120007136827

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Presentation] k-space power distributionを用いたCompressed Sensingサンプリング最適化手法の検討2014

    • Author(s)
      玉田大輝,巨瀬勝美
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      ホテルグランヴィア京都(京都市下京区)
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Coupled circuit simulation of Z-and X-gradient eddy currents in a 9.4T narrow-bore MRI system2014

    • Author(s)
      アクラム エムディ シャハダト ホサイン,寺田康彦,巨瀬勝美
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      ホテルグランヴィア京都(京都市下京区)
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Temporal-spatial responses of planar X-gradient eddy currents by solid angle coupled circuit method2014

    • Author(s)
      アクラム エムディ シャハダト ホサイン,寺田康彦,巨瀬勝美
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      ホテルグランヴィア京都(京都市下京区)
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 高次の静磁場不均一性を考慮したSelf-Calibrated Compressed Sensingアルゴリ ズムの開発2014

    • Author(s)
      玉田大輝,巨瀬勝美
    • Organizer
      第42回日本磁気共鳴医学会大会
    • Place of Presentation
      ホテルグランヴィア京都(京都市下京区)
    • Year and Date
      2014-09-18 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] 高温超伝導バルク磁石におけるマイスナー効果を考慮した勾配磁場コイルの開発2014

    • Author(s)
      玉田大輝,仲村高志,巨瀬勝美
    • Organizer
      第18回NMRマイクロイメージング研究会
    • Place of Presentation
      金沢勤労者プラザ(石川県金沢市)
    • Year and Date
      2014-08-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] Measurements of the Magnetic Field Distribution in the High Tc Superconducting Bulk Magnet During the Magnetization Process2013

    • Author(s)
      玉田大輝, 仲村高志, 巨瀬勝美
    • Organizer
      International Society for Magnetic Resonance in Medicine
    • Place of Presentation
      Salt Lake City, Utah, USA
    • Year and Date
      2013-04-22
    • Related Report
      2012 Annual Research Report
  • [Presentation] MR microscopy using a high Tc superconducting bulk magnet.2013

    • Author(s)
      D. Tamada, T. Nakamura, K. Kose
    • Organizer
      12th International Conference on Magnetic Resonance Microscopy
    • Place of Presentation
      Fitzwilliam College, Cambridge, UK
    • Related Report
      2013 Annual Research Report
  • [Presentation] Measurements of the Magnetic Field Distribution in the High Tc Superconducting Bulk Magnet During the Magnetization Process2013

    • Author(s)
      Daiki Tamada, Takashi Nakamura, Katsumi Kose
    • Organizer
      21th Annual Meeting & Exhibition (ISMRM)
    • Place of Presentation
      Salt lake city,USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] MR Microimaging Using a High Tc Superconducting Bulk Magnet with Compressed Sensing2013

    • Author(s)
      Daiki Tamada, Takashi Nakamura, Katsumi Kose
    • Organizer
      21th Annual Meeting & Exhibition (ISMRM)
    • Place of Presentation
      Salt lake city,USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] 新規設計による高温超伝導バルク磁石を用いたMRIの開発2013

    • Author(s)
      玉田大輝,巨瀬勝美,柳陽介,伊藤佳孝,仲村高志
    • Organizer
      第17回NMRマイクロイメージング研究会
    • Place of Presentation
      キャンパスイノベーションセンター,田町(東京)
    • Related Report
      2013 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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