Development of a mouse MRI using a superconducting bulk magnet
| Project/Area Number |
24360034
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied physics, general
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| Research Institution | University of Tsukuba |
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Principal Investigator |
KOSE Katsumi 筑波大学, 数理物質系, 教授 (60186690)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Takashi 理化学研究所, 分子構造解析ユニット, 専任技師 (60321791)
TERADA Yasuhiko 筑波大学, 数理物質系, 助教 (20400640)
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| Research Collaborator |
TAMADA Daiki
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
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| Keywords | MRI / 高温超伝導 / 超伝導磁石 / バルク磁石 |
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| Outline of Final Research Achievements |
We developed a magnetic resonance (MR) microscope using a high critical-temperature superconducting bulk magnet. The bulk magnet comprises six annular bulk superconductors (two end bulk magnets : 60 mm OD, 28 mm ID, and 23 mm height, four inner bulk magnets : 60 mm OD, 36 mm ID, and 18.5 mm height) made of c-axis oriented single-domain EuBa2Cu3Oy crystals. The magnet was energized using a superconducting NMR magnet for high-resolution NMR spectroscopy operating at 4.7 T. The trapped magnetic field was homogenized using a single-layer shim-coil developed in our group. The inhomogeneity of the trapped magnetic field measured with MR imaging was 15.4 ppm (peak-to-peak) in the 8.4 mm diameter and 10 mm long cylindrical region. Three-dimensional MR images of a chemically-fixed mouse fetus acquired with 50 micrometer cube voxels demonstrated the usefulness of our system.
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Report
(4 results)
Research Products
(13 results)
