| Project/Area Number |
24360075
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Fluid engineering
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
TSUKIYA Tomonori 独立行政法人国立循環器病研究センター, 研究所, 室長 (00311449)
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| Co-Investigator(Kenkyū-buntansha) |
HORIGUCHI Hironori 大阪大学, 基礎工学研究科, 准教授 (60314837)
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| Co-Investigator(Renkei-kenkyūsha) |
MIZUNO Toshihide 国立循環器病研究センター, 研究所, 室長 (40426515)
TAKEWA Yoshiaki 国立循環器病研究センター, 研究所, 室長 (20333405)
TSTSUMI Eisuke 国立循環器病研究センター, 研究所, 部長 (00216996)
TSUJIMOTO Yoshinobu 大阪大学, 基礎工学研究科, 教授 (50112024)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥10,920,000 (Direct Cost: ¥8,400,000、Indirect Cost: ¥2,520,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2013: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 人工心臓 / 血液 / 数値流体力学 / 遠心ポンプ / 流体機械 / 医療機器 / ポンプ / 右心補助 / 動圧軸受 / 両心補助 |
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| Outline of Final Research Achievements |
A implantable centrifugal blood pump was developed as a blood pump for an implantable right ventricular assit device, that are required to make a mechanical circulatory support for severe heart failure. The centrifugal blood pump was designed with the aid of computational fluid dynamics software, and a prototype was manufactured. The basic performances as a blood pump for right ventricular assist was confirmed, while a minor modification was needed in the design of the hydrodynamic bearings that is one of the key components to obtain sufficient antithrombogenicity for a long-term use. The modified pump demonstrated that the amount of broked blood cells by passing through the pump was within a clinically acceptable range.
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