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Estimating removal of unculturable waterborne virus during drinking water treatment by using VLPs

Research Project

Project/Area Number 24360211
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Civil and environmental engineering
Research InstitutionHokkaido University

Principal Investigator

MATSUSHITA Taku  北海道大学, 工学(系)研究科(研究院), 准教授 (30283401)

Co-Investigator(Kenkyū-buntansha) MATSUI Yoshihiko  北海道大学, 大学院工学研究院, 教授 (00173790)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥16,900,000 (Direct Cost: ¥13,000,000、Indirect Cost: ¥3,900,000)
Fiscal Year 2014: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2013: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2012: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Keywords土木環境システム / 水質汚濁・土壌汚染防止・浄化 / ウイルス / 浄水処理
Outline of Final Research Achievements

Recombinant norovirus VLP and some waterborne pathogenic viruses (poliovirus and adenovirus) were artificially added to a wide variety of raw water for drinking water that were obtained from actual drinking water treatment plants in Japan, and virus removal during conventional coagulation-sedimentation treatment was investigated. The removals of the waterborne pathogenic viruses were found to be 0-2.5 logs, which were lower than that of bacteriophage MS2 but higher than that of bacteriophage phiX174. The observations suggest that not MS2 but phiX174 could be a conservative surrogate of the waterborne pathogenic viruses. However, further study is still required for the suggestion by using a wide variety of treatment conditions.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (19 results)

All 2014 2013 2012

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 1 results) Presentation (13 results) (of which Invited: 1 results)

  • [Journal Article] Virus removal by an in-line coagulation-ceramic microfiltration process with high-basicity polyaluminum coagulation pretreatment2014

    • Author(s)
      Shirasaki, N., Matsushita, T., Matsui, Y., Urasaki, T., Kimura, M. and Ohno, K.
    • Journal Title

      Water Science and Technology: Water Supply

      Volume: 14(3) Issue: 3 Pages: 429-437

    • DOI

      10.2166/ws.2013.218

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improved virus removal by high-basicity polyaluminum coagulants compared to commercially available aluminum-based coagulants2014

    • Author(s)
      Shirasaki, N., Matsushita, T., Matsui, Y., Oshiba, A., Marubayashi, T. and Sato, S.
    • Journal Title

      Water Research

      Volume: 48 Pages: 375-386

    • DOI

      10.1016/j.watres.2013.09.052

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Investigating norovirus removal by microfiltration, ultrafiltration, and precoagulation-microfiltration processes using recombinant norovirus virus-like particles and real-time immuno-PCR2013

    • Author(s)
      Matsushita, T., Shirasaki, N., Tatsuki, Y. and Matsui, Y.
    • Journal Title

      Water Research

      Volume: 47 Issue: 15 Pages: 5819-5827

    • DOI

      10.1016/j.watres.2013.07.004

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adsorptive virus removal with super-powdered activated carbon2013

    • Author(s)
      Matsushita, T.
    • Journal Title

      Separation and Purification Technology

      Volume: 107 Pages: 79-84

    • DOI

      10.1016/j.seppur.2013.01.017

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ウイルス処理に有効な新規アルミニウム系凝集剤の開発2012

    • Author(s)
      白崎伸隆,松下拓,松井佳彦,大芝淳
    • Journal Title

      土木学会論文集G (環境)

      Volume: 68(7)

    • NAID

      130004962424

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Difference in behaviors of F-specific DNA and RNA bacteriophages during coagulation-rapid sand filtration and coagulation-microfiltration processes2012

    • Author(s)
      Shirasaki, N., Matsushita, T., Matsui, Y., Urasaki, T., and Ohno, K.
    • Journal Title

      Water Science and Technology : Water Supply

      Volume: 12(5) Issue: 5 Pages: 666-673

    • DOI

      10.2166/ws.2012.041

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] Development of novel high-basicity polyaluminum chloride for effective virus removal2014

    • Author(s)
      Marubayashi, T., Shirasaki, N., Matsushita, T., Matsui, Y. and Oshiba, A.
    • Organizer
      IWA World Water Congress
    • Place of Presentation
      Lisbon, PortugalLisbon, Portugal
    • Year and Date
      2014-09-21 – 2014-09-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Development of novel high-basicity polyaluminum chloride for effective virus removal2014

    • Author(s)
      Shirasaki, N., Marubayashi, T., Matsushita, T., Matsui, Y. and Oshiba, A.
    • Organizer
      IWA World Water Congress
    • Place of Presentation
      Lisbon Convention Centre, Lisbon, Portugal
    • Related Report
      2013 Annual Research Report
  • [Presentation] 全国の水道原水を用いた水系感染症ウイルスの凝集処理性評価及びウイルス処理性指標の模索2014

    • Author(s)
      丸林拓也, 白崎伸隆, 松下拓, 松井佳彦
    • Organizer
      第48回日本水環境学会年会
    • Place of Presentation
      東北大学, 仙台
    • Related Report
      2013 Annual Research Report
  • [Presentation] Evaluating norovirus removal during drinking water treatment by using recombinant norovirus virus-like particles.2013

    • Author(s)
      Matsushita, T., Shirasaki, N., Matsui, Y., Tatsuki, Y. and Oshiba, A.
    • Organizer
      2nd International Doctoral Symposium with Partner Universites
    • Place of Presentation
      Hokkaido University, Sapporo, Japan
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Estimating norovirus removal performance in an in-line coagulation-ceramic microfiltration process by using recombinant norovirus VLPs and immuno-PCR method2013

    • Author(s)
      Shirasaki, N., Matsushita, T., Matsui, Y. and Tatsuki, Y.
    • Organizer
      IWA Membrane Technology Conference (IWA-MTC 2013)
    • Place of Presentation
      Westin Harbour Castle, Toronto, Canada
    • Related Report
      2013 Annual Research Report
  • [Presentation] ウイルス様粒子とImmuno-PCR法を併用したノロウイルスの膜ろ過処理性評価及び処理メカニズムの解明2013

    • Author(s)
      白崎伸隆, 田附雄一, 松下拓, 松井佳彦
    • Organizer
      第50回環境工学研究フォーラム
    • Place of Presentation
      北海道大学, 札幌
    • Related Report
      2013 Annual Research Report
  • [Presentation] インライン凝集-セラミック膜ろ過処理によるノロウイルス粒子の効果的除去2013

    • Author(s)
      白崎伸隆,田附雄一,松下拓,松井佳彦
    • Organizer
      第68回土木学会年次学術講演会
    • Place of Presentation
      日本大学, 千葉
    • Related Report
      2013 Annual Research Report
  • [Presentation] アルミニウム系及び鉄系凝集剤の塩基度がウイルスの処理性に与える影響2013

    • Author(s)
      丸林拓也, 白崎伸隆, 松下拓, 松井佳彦
    • Organizer
      第47回日本水環境学会年会
    • Place of Presentation
      大阪工業大学(大阪府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Virus removal by a coagulation-microfiltration process2012

    • Author(s)
      Shirasaki, N., Matsushita, T., and Matsui, Y.
    • Organizer
      The 4th IWA Asia-Pacific Young Water Professionals Conference 2012
    • Place of Presentation
      Tokyo International Forum (Japan)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effective removal of virus by high-basicity polyaluminum coagulation treatment2012

    • Author(s)
      Shirasaki, N., Matsushita, T., Matsui, Y., and Sato, S.
    • Organizer
      Particle Separation Conference
    • Place of Presentation
      Jerusalem Church (Germany)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ウイルス処理に有効な新規アルミニウム系凝集剤の開発2012

    • Author(s)
      白崎伸隆, 松下拓, 松井佳彦, 大芝淳
    • Organizer
      第49回環境工学研究フォーラム
    • Place of Presentation
      京都大学(京都府)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ウイルス様粒子と新規イムノPCR法を併用したヒトノロウイルスの膜ろ過処理性評価2012

    • Author(s)
      白崎伸隆, 田附雄一, 松下拓, 松井佳彦
    • Organizer
      第67回土木学会年次学術講演会
    • Place of Presentation
      名古屋大学(愛知県)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 凝集剤中のアルミニウム形態がウイルスの処理性に与える影響2012

    • Author(s)
      白崎伸隆, 大芝淳, 松下拓, 松井佳彦
    • Organizer
      第63回全国水道研究発表会
    • Place of Presentation
      くにびきメッセ(島根県)
    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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