| Project/Area Number |
24360342
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Kobe University |
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Principal Investigator |
AKIHIKO Kondo 神戸大学, 工学(系)研究科(研究院), 教授 (40205547)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Tsutomu 神戸大学, 大学院工学研究科, 准教授 (90436551)
OGINO Chiaki (MATSUMOTO Takuya / YAMADA Ryosuke) 神戸大学, 大学院工学研究科, 准教授 (00313693)
松本 拓也 神戸大学, 学内共同利用施設等, 助教 (40727161)
山田 亮祐 神戸大学, 自然科学系先端融合研究環, 助教 (40608626)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2012: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Keywords | バイオリファイナリー / 細胞表層提示 / バイオリファイなリー / オーム解析 / バイオマス |
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| Outline of Final Research Achievements |
The development of efficient utilization of renewable biomass resources is one of the important issues to overcome the environmental / energy problems. We have developed cell surface display system, which is a powerful tool due to endowing the biomass degrading activity on the host cells. Here, we developed comprehensive approaches to develop cell surface display applicable for other useful microorganisms. As a results, several kinds of anchor proteins have been developed and enables them to providing biomass degrading activity. In addition, using cell surface engineered microorganisms, direct production from biomass was achieved.
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