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Study on x-ray computed tomography with ingredient decomposing radiography by multi-variate analysis

Research Project

Project/Area Number 24360394
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Nuclear engineering
Research InstitutionKyoto University

Principal Investigator

KANNO Ikuo  京都大学, 工学(系)研究科(研究院), 教授 (50234167)

Co-Investigator(Kenkyū-buntansha) IIDA Hidehiro  独立行政法人国立循環器病研究センター, 画像診断医学部, 画像診断医学部長 (30322720)
渡辺 賢一  名古屋大学, 工学(系)研究科(研究院), 准教授 (30324461)
Co-Investigator(Renkei-kenkyūsha) WATANABE Kenichi  名古屋大学, 工学研究科, 准教授 (30324461)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2014: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2013: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2012: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
KeywordsX線 / コンピュータ断層撮影 / 被曝 / 透過測定 / エネルギー分解 / 透過撮影 / 画像再構成 / 被曝量 / 多変量解析 / 低被曝 / エネルギー分解CT / 物質弁別
Outline of Final Research Achievements

An acrylic phantom had a diameter of 3 cm. A 5 mm diameter iodine region and a 2 mm diameter aluminum rod were in the phantom. Employed transXend detector consisted of six Si(Li) segment detectors with the dimensions of 10x10x1 mm. Two dimensional maps were obtained for acrylic-iodine thicknesses, and acrylic-aluminum thicknesses with x and y axises as ratios of measured electric currents by the segment detectors. The acrylic phantom was scanned from 0 and 90 degrees with the scan step of 0.4 mm. The thicknesses of acrylic, iodine and aluminum at each scan point were estimated, and the thickness distributions of materials were obtained. With these thickness distributions, tomographies were reconstructed by ML-EM method. With our method, tomograpies were obtained by a small number of transmission measurements.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (24 results)

All 2015 2014 2013 2012 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 4 results) Presentation (16 results) (of which Invited: 4 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Low-dose Exposure Energy-Resolved X-ray Computed Tomography using a Contrast Agent with a High-energy K-edge2014

    • Author(s)
      Y.Yamashita, I. Kanno, 他.
    • Journal Title

      Journal of Nuclear Science and Technology

      Volume: 51 Issue: 1 Pages: 91-97

    • DOI

      10.1080/00223131.2013.849621

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Measurement of effective atomic numbers using energy-resolved computed tomography2014

    • Author(s)
      Yoshiki Yamashita, Masashi Kimura, Masaru Kitahara, Takumi Hamaguchi, Ikuo Kanno,Masahiko Ohtaka, Makoto Hashimoto, Kuniaki Ara and Hideaki Onabe
    • Journal Title

      Journal of Nuclear Science and Technology

      Volume: 51 Issue: 10 Pages: 1256-1263

    • DOI

      10.1080/00223131.2014.919881

    • NAID

      120005624357

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Energy- resolved Computed Tomography Measurements of Iron Solution and Adipose as a Simulation for Estimating the Iron Concentration in the Human Liver2013

    • Author(s)
      Y.Yamashita, I. Kanno, 他.
    • Journal Title

      Journal of Nuclear Science and Technology

      Volume: 50 Issue: 4 Pages: 376-380

    • DOI

      10.1080/00223131.2013.773163

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Computed Tomography Reconstruction from Two Transmission Measurements for Iodine-marked Cancer Detection2013

    • Author(s)
      I.Kanno, K.Shima, 他.
    • Journal Title

      Journal of Nuclear Science and Technology

      Volume: 50 Issue: 10 Pages: 1020-1033

    • DOI

      10.1080/00223131.2013.830077

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Low Dose Exposure Diagnosis with a transxend Detector Aiming for Iodine - marked Cancer Detection2012

    • Author(s)
      I. Kanno, H. Shilazaki, R. Imaura, Y. Yamashita, K. Shima, M. ohtaka, M. Hashiioto. K. Ara and H. Onabe
    • Journal Title

      J. Nucl. Sci. Technol.

      Volume: 49 Pages: 937-946

    • NAID

      120005323011

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] エネルギー分解 X 線コンピュータ断層撮影法を用いた種々の物質の実効原子番号測定2015

    • Author(s)
      神野郁夫,井上福太郎,丸山能央,木村優志,大高雅彦,橋本 周,荒 邦章,尾鍋秀明
    • Organizer
      日本原子力学会
    • Place of Presentation
      茨城大学
    • Year and Date
      2015-03-20 – 2015-03-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] エネルギー分解X線コンピュータ断層撮影法による造影剤量低減の可能性2015

    • Author(s)
      伊良皆 拓,桑原 潤一,神野 郁夫,伊藤 秋男,中村 光宏,平岡 眞寛
    • Organizer
      応用物理学会
    • Place of Presentation
      東海大学
    • Year and Date
      2015-03-11 – 2015-03-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 第三世代コンピュータ断層撮影に対応する電流測定・エネルギー分解X線検出器の開発2015

    • Author(s)
      叶井 絵梨,神野 郁夫,山下 良樹,小川 剛史,眞正 浄光
    • Organizer
      応用物理学会
    • Place of Presentation
      東海大学
    • Year and Date
      2015-03-11 – 2015-03-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 健康診断における癌のスクリーニングを目的とした低被ばくX線コンピュータ断層撮影法の開発2015

    • Author(s)
      船引 綾乃,山内 一輝,神野 郁夫,大高 雅彦,橋本 周,荒 邦章,尾鍋 秀明
    • Organizer
      応用物理学会
    • Place of Presentation
      東海大学
    • Year and Date
      2015-03-11 – 2015-03-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] Current-mode transXend detector for Energy Resolved CT and its applications2014

    • Author(s)
      I. Kanno
    • Organizer
      7th Korea-Japan Joint Meeting of Medical Physics
    • Place of Presentation
      大韓民国プサン
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] フラットパネル検出器を搭載した汎用CT装置による実効原子番号測定2014

    • Author(s)
      伊良皆拓,桑原潤一,神野郁夫,伊藤秋男,中村光宏,平岡眞寛
    • Organizer
      応用物理学会
    • Place of Presentation
      北海道大学
    • Year and Date
      2014-09-17 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Effective Atomic Number Measurement with Energy-resolved X-ray Computed Tomography2014

    • Author(s)
      I. Kanno, Y. Yamashita, M. Kimura, F. Inoue
    • Organizer
      New Developments in Photo Detectors
    • Place of Presentation
      フランス・ツール
    • Year and Date
      2014-06-30 – 2014-07-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] 電流モード検出器transXendを用いたエネルギー分解コンピュータ断層撮影法2013

    • Author(s)
      神野郁夫
    • Organizer
      日本学術振興会第186委員会
    • Place of Presentation
      放射線医学総合研究所
    • Year and Date
      2013-11-06
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Computed Tomography of Acrylic Phantom with Iodine and Aluminum Resoctructed by Two Transmission Measurements2013

    • Author(s)
      I. Kanno, K. Shima, et al.
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      ソウル
    • Year and Date
      2013-10-30
    • Related Report
      2013 Annual Research Report
  • [Presentation] Measurement of Atomic Numbers Using Energy-resolved Computed Tomography2013

    • Author(s)
      Y. Yamashita, I. Kanno, et al.
    • Organizer
      IEEE Nuclear Science Symposium and Medical Imaging Conference
    • Place of Presentation
      ソウル
    • Year and Date
      2013-10-30
    • Related Report
      2013 Annual Research Report
  • [Presentation] エネルギー分解CTによる実効原子番号測定2013

    • Author(s)
      山下良樹,神野郁夫,他.
    • Organizer
      応用物理学会
    • Place of Presentation
      同志社大学
    • Year and Date
      2013-09-16
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 高エネルギーK 吸収端造影剤とエネルギー分解による低被曝化CT 法2013

    • Author(s)
      山下良樹,神野郁夫,他.
    • Organizer
      応用物理学会
    • Place of Presentation
      同志社大学
    • Year and Date
      2013-09-16
    • Related Report
      2013 Annual Research Report
  • [Presentation] 多種シンチレータ平面transXend 検出器を用いた物質厚さ推定の可能性2013

    • Author(s)
      北原理,神野郁夫,他.
    • Organizer
      応用物理学会
    • Place of Presentation
      同志社大学
    • Year and Date
      2013-09-16
    • Related Report
      2013 Annual Research Report
  • [Presentation] エネルギー分解CTによる実効原子番号測定2013

    • Author(s)
      神野郁夫,島一成,他.
    • Organizer
      日本原子力学会
    • Place of Presentation
      八戸工業大学
    • Year and Date
      2013-09-04
    • Related Report
      2013 Annual Research Report
  • [Presentation] transXend検出器 の開発と低被曝CTへの応用2013

    • Author(s)
      神野郁夫
    • Organizer
      日本医学物理学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2013-04-13
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] 超低被曝量診断を目指したtransXend検出器出力の多変量解析によるX線画像化2012

    • Author(s)
      神野郁夫, 島一成, 山下良樹, 大高雅彦, 橋本周, 荒邦章, 尾鍋秀明
    • Organizer
      日本原子力学会
    • Place of Presentation
      広島大学
    • Year and Date
      2012-09-22
    • Related Report
      2012 Annual Research Report
  • [Book] 放射線計測ハンドブック 第4版2013

    • Author(s)
      神野郁夫,木村逸郎,阪井英次 訳
    • Total Pages
      870
    • Publisher
      オーム社
    • Related Report
      2013 Annual Research Report
  • [Remarks] 神野郁夫

    • URL

      http://www.nucleng.kyoto-u.ac.jp/People/Kanno/kanno.html

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
  • [Patent(Industrial Property Rights)] 特許2014

    • Inventor(s)
      神野郁夫
    • Industrial Property Rights Holder
      神野郁夫
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-152170
    • Filing Date
      2014-07-25
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2012-04-24   Modified: 2019-07-29  

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