Testing a teleological hypothesis of cardiolocomotor phase synchronization during exercise

• Project/Area Number: 24370100
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Applied anthropology
• Research Institution: Yamagata University
• Principal Investigator: NIIZEKI KYUICHI 山形大学, 理工学研究科, 教授 (00228123)
• Co-Investigator(Kenkyū-buntansha): SAITOH Tadashi 山形大学, 大学院理工学研究科, 助教 (20454770)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2012: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
• Keywords: 心拍リズム / 運動リズム / 位相同期 / 筋組織ヘモグロビン濃度 / 筋組織ヘモグロビン / ガス交換 / トレッドミル運動

Outline of Final Research Achievements

The present study aimed to test a teleological hypothesis of phase synchronization between cardiac and locomotor rhythm observed during rhythmic exercise. Twenty five subjects performed incremental grade walking test on a treadmill at a constant speed for 20 min. Breath-by-breath gas exchange parameters and changes in oxy- and deoxy-hemoglobin at the soleus muscle by NIRS were measured. The changes in gas exchange parameters and NIRS indices during cardiac-locomotor synchronization (CLS) were evaluated as the differences between the observed and predicted values, which were obtained by plotting each desynchronized parameter against time and fitted with a least square regression line. Lower level of ventilatory equivalent for O2 and relative increase in deoxyhemoglobin and decrease in oxyhemoglobin were observed during CLS episode. These results suggest that CLS improves the pulmonary gas exchange efficiency and induces a shift toward more aerobic oxidative metabolism in the muscle.

Research Products

• [Journal Article] Cardiolocomotor phase synchronization during rhythmic exercise (2014)
  • Author(s): Niizeki K and Saitoh T.
  • Journal Title: The Journal of Physical Fitness and Sports Medicine Volume: 3 Issue: 1 Pages: 11-20
  • DOI: 10.7600/jpfsm.3.11
  • NAID: 130003397894
  • ISSN: 2186-8123, 2186-8131
  • Peer Reviewed
• [Journal Article] Estimation of Melanin and Hemoglobin Using Spectral Reflectance Images Reconstructed from a Digital RGB Image by the Wiener Estimation Method (2013)
  • Author(s): Izumi Nishidate, Takaaki Maeda, Kyuichi Niizeki, and Yoshihisa Aizu
  • Journal Title: Sensors Volume: 13 Issue: 6 Pages: 7902-7915
  • DOI: 10.3390/s130607902
  • NAID: 120005323273
  • Peer Reviewed
• [Journal Article] Visualization of peripheral vasodilative indices in human skin by use of red, green, blue images (2013)
  • Author(s): Izumi Nishidate, Noriyuki Tanaka, Tatsuya Kawase, Takaaki Maeda, Tomonori Yuasa, Yoshihisa Aizu, Tetsuya Yuasa, Kyuichi Niizeki
  • Journal Title: Journal of Biomedical Optics Volume: 18 Issue: 6 Pages: 61220-61220
  • DOI: 10.1117/1.jbo.18.6.061220
  • Peer Reviewed
• [Journal Article] Effects of cardiolocomotor coupling on gas exchange efficiency and energy metabolism. (2012)
  • Author(s): Niizeki K, Kusakabe S, Onodera M, Kouhata K, Saitoh T.
  • Journal Title: Proceedings of The 27^<th> Symposium on Biological and Physiological Engineering Volume: 27 Pages: 280-284
• [Journal Article] Effect of hyperventilation on oxygen uptake kinetics during cycling exercise. (2012)
  • Author(s): Saitoh T, Niizeki K.
  • Journal Title: Proceedings of The 27^<th> Symposium on Biological and Physiological Engineering Volume: 27 Pages: 461-462
• [Presentation] Experimental validation of teleological hypothesis of cardiolocomotor coupling: effects on gas exchange and muscle deoxygenation during treadmill walking (2015)
  • Author(s): Niizeki K and Saitoh T.
  • Organizer: 第92回日本生理学会大会
  • Place of Presentation: 神戸国際会議場
  • Year and Date: 2015-03-21 – 2015-03-23
• [Presentation] PetCO2制御による呼吸性アルカローシスが高強度運動開始時の酸素摂取量応答に及ぼす影響 (2014)
  • Author(s): 矢内潤，新関久一，齊藤直
  • Organizer: 生体医工学シンポジウム2014
  • Place of Presentation: 東京農工大
  • Year and Date: 2014-09-26 – 2014-09-27
• [Presentation] Analyzing postural control during voluntary sway in the anteroposterior axis in young and elderly adults (2014)
  • Author(s): Niizeki K,Kouhata K, Gotoh A, and Saitoh T.
  • Organizer: LEシンポジウム2014
  • Place of Presentation: 金沢大学
  • Year and Date: 2014-09-17 – 2014-09-19
• [Presentation] Effects of transient cardiolocomotor coupling on gas exchange and muscle deoxygenation during treadmill exercise: a preliminary observation in an elderly subject. (2014)
  • Author(s): Niizeki K, Hoshi A, and Saitoh T.
  • Organizer: European College of Sports Science
  • Place of Presentation: アムステルダム RAI コンベンションセンター，オランダ
  • Year and Date: 2014-07-02 – 2014-07-05
• [Presentation] Phase coherency of respiratory sinus arrhythmia during food ingestion and gum chewing (2014)
  • Author(s): Kanno J, Koshiba Y, Saitoh T., and Niizeki K.
  • Organizer: 第53回日本生体医工学会大会
  • Place of Presentation: 仙台国際センター
  • Year and Date: 2014-06-24 – 2014-06-26
• [Presentation] Validity of combining triaxial accelerometry and heart rate in the assessment of the dynamics of energy expenditure during walking (2014)
  • Author(s): Koshiba Y , Kanno J, Saitoh T., and Niizeki K.
  • Organizer: 第53回日本生体医工学会大会
  • Place of Presentation: 仙台国際センター
  • Year and Date: 2014-06-24 – 2014-06-26
• [Presentation] Frequency-dependent effects of heel rasing maneuver on orthostatic cardiovascular responses. (2014)
  • Author(s): Niizeki K, Onodera M, and Saitoh T.
  • Organizer: 91st Annual Meeting of Physiological Science
  • Place of Presentation: 鹿児島大学郡元キャンパス
• [Presentation] Effects of heel raising maneuver on hemodynamic and autonomic responses to the upright posture. (2013)
  • Author(s): Onodera M, Kouhata K, Saitoh T, and Niizeki K.
  • Organizer: 35th Annual International Conference of the IEEE Engineering in Medicine & Biology Society
  • Place of Presentation: 大阪国際会議場
• [Presentation] Analysis of postural control during voluntary sway of the anteroposterior axis in young and elderly humans. (2013)
  • Author(s): Kouhata K, Onodera M, Saitoh T, and Niizeki K
  • Organizer: 35th Annual International Conference of the IEEE Engineering in Medicine & Biology Society
  • Place of Presentation: 大阪国際会議場
• [Presentation] Effect of a controlled respiratory rate on oxygen uptake kinetics during cycling exercise. (2013)
  • Author(s): Saitoh T, Kobayashi H, Yanai J, Nomura R, Tsutui H, Takana H, and Niizeki K.
  • Organizer: 37th Congress of International Union of Physiological Sciences
  • Place of Presentation: International Convention Centre, Birmingham, UK
• [Presentation] Comparison of oxygen utilization during magnetic muscle stimulation with that during handgrip exercise. (2013)
  • Author(s): Saitoh T and Niizeki K.
  • Organizer: 60th Annual Meeting of American College Sports Medicine
  • Place of Presentation: Indiana Convension Center,Indianapolis, USA
• [Presentation] Effect of hyperventilation on oxygen uptake kinetics during cycling exercise. (2012)
  • Author(s): Saitoh T, Niizeki K.
  • Organizer: The 27th Symposium on Biological and Physiological Engineering
  • Place of Presentation: 北海道大学学術交流会館(北海道)
  • Year and Date: 2012-09-21
• [Presentation] Effects of cardiolocomotor coupling on gas exchange efficiency and energy metabolism. (2012)
  • Author(s): Niizeki K, Kusakabe S, Onodera M, Kouhata K, Saitoh T.
  • Organizer: The 27^<th> Symposium on Biological and Physiological Engineering
  • Place of Presentation: 北海道大学学術交流会館(北海道)
  • Year and Date: 2012-09-20
• [Presentation] 呼吸性不整脈の位相差ゆらぎに基づくメンタルストレス評価 (2012)
  • Author(s): 新関久一,菊地聖也,今野稚奈,原田直季,齊藤直
  • Organizer: 第23回日本臨床モニター学会総会
  • Place of Presentation: 横浜シンポジア(神奈川県)
  • Year and Date: 2012-04-21