| Budget Amount *help |
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2014: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2012: ¥7,410,000 (Direct Cost: ¥5,700,000、Indirect Cost: ¥1,710,000)
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| Outline of Final Research Achievements |
In this project, epidemiological studies on canine distemper virus (CDV), studies on its pathogenicity and studies on effect of vaccine on large animals were carried out. 1) CDV infection among domestic dogs in Vietnam, wild animals in Kochi and Wakayama and domestic dogs in Japan were analyzed. 2) Efficacy and safety of vaccine for dogs on tigers and lions were evaluated. 3) It was proved that feline SLAM and humane C-type lectins, DC-SIGN and DC-SIGNR, functioned as receptors for CDV. 4) ELISA to detect antibody to CDV in all mammalian species was developed. 5) Method for evaluation of pathogenicity of CDV was established.
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