Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2014: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2013: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2012: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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Outline of Final Research Achievements |
We showed the possibility that Aβ43, an essential molecule for pathological process of Alzheimer’s disease, could induce channel activity. Also, we successfully prepared Aβ oligomers by PICUP (photo-induced cross-linking of unmodified proteins) method and established the purification procedure with HPLC.
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