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Perspectives on palliative care: Clinical practice guidelines and the issue of paient' preference and quality of life

Research Project

Project/Area Number 24390128
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Medical sociology
Research InstitutionKyoto University

Principal Investigator

Miyazaki Kikuko  京都大学, 医学(系)研究科(研究院), 非常勤講師 (70464229)

Co-Investigator(Kenkyū-buntansha) 下妻 晃二郎  立命館大学, 生命科学部, 教授 (00248254)
大住 省三  独立行政法人国立病院機構四国がんセンター(臨床研究センター), その他部局等, その他 (20416473)
鈴鴨 よしみ  東北大学, 医学(系)研究科(研究院), 准教授 (60362472)
中山 健夫  京都大学, 医学(系)研究科(研究院), 教授 (70217933)
Co-Investigator(Renkei-kenkyūsha) YAMAZAKI Hiroshi  信州大学, 医学部, 准教授 (30378773)
Research Collaborator IKENAGA Masayuki  
HORIMATSU Takahiro  
MATSUMOTO Shigemi  
SATO Toshiya  
UESHIMA Kenji  
KAWAMURA Takashi  
KASAI Hiroi  
KIYOTO Sachiko  
NISHINA Tomohiro  
NAWATA Osamu  
TOUYAMA Mayumi  
TOMINARI Shinjiro  
HINATA Miwa  
SEBOKU Tami  
TOKUMASU Hironobu  
KURIYAMA Akira  
KONDA Manako  
KANAZAWA Natsuko  
KITOU Kumiko  
KIMOTO Michio  
TOKORO Akihiro  
HANAKI Hiroshi  
KIDA Morio  
NOZAKI Akira  
KIRISHIMA Yoshihiko  
SHIMIZU Yoshihiro  
KOMORI Eisaku  
KATAYAMA Yuko  
Project Period (FY) 2012-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2015: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2013: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2012: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Keywords緩和ケア / 倦怠感治療 / QOL / 診療ガイドライン / RCT / 患者の選好 / エビデンス総体 / 患者中心の医療 / 患者の価値観 / 多施設共同研究 / 緩和医療(ケア) / ランダム化比較試験 / EORTC QLQ-C15-PAL / インタビュー調査 / EORTC QLQ-C15-Pal / エビデンス診療ギャップ
Outline of Final Research Achievements

The aim of this study was to provide suggestions regarding palliative care, from the perspective of both patients and health professionals. Comparisons of various analyses of the contents of clinical practice guidelines have shown that those who created the guidelines had considerably different sense of values regarding quality of life from that of their patients. An interview survey of patients with colorectal cancer showed that all patients with stage IV cancer who had reached remission gained the understanding of their employers and continued working. The connection with society is important even when patients are in serious conditions. Clinical studies have examined the effectiveness of steroid doses commonly used in Japan for the treatment of fatigue. Actual clinical research practice has specifically revealed the issues and challenges of clinical studies conducted upon obtaining the cooperation of terminally ill patients.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (38 results)

All 2017 2016 2015 2014 2013 2012 Other

All Journal Article (4 results) (of which Peer Reviewed: 2 results) Presentation (21 results) (of which Int'l Joint Research: 3 results,  Invited: 8 results) Remarks (13 results)

  • [Journal Article] Superiority of laparoscopic proximal gastrectomy with hand-sewn esophagogastrostomy over total gastrectomy in improving postoperative body weight loss and quality of life2017

    • Author(s)
      Nishigori T, Okabe H, Tsunoda S, Shinohara H, Obama K, Hosogi H, Hisamori S,
    • Journal Title

      Surg Endosc

      Volume: - Issue: 9 Pages: 3664-3672

    • DOI

      10.1007/s00464-016-5403-y

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 質的研究とミクスド・メソッド 公正な研究活動2016

    • Author(s)
      宮崎貴久子
    • Journal Title

      子どもの健康科学

      Volume: 16 Pages: 9-15

    • Related Report
      2016 Annual Research Report
  • [Journal Article] QOL評価学の基本2016

    • Author(s)
      宮崎貴久子
    • Journal Title

      医薬ジャーナル

      Volume: 52 Pages: 123-126

    • NAID

      40021006677

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 「QOL研究から行動医学に向けて」にあたって2015

    • Author(s)
      宮崎貴久子
    • Journal Title

      Japanese Journal of Behavioral Medicine

      Volume: 21 Issue: 1 Pages: 2-3

    • DOI

      10.11331/jjbm.21.2

    • NAID

      130005065631

    • ISSN
      1341-6790, 2188-0085
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] Description of quality of life and patient preference in Japanese cancer clinical practice guideline: A content analysis2016

    • Author(s)
      Miyazaki K, Hinata M, Kyoto CPGs study group, Nakayama T.
    • Organizer
      International Society for Quality of Life Researc
    • Place of Presentation
      Copenhagen
    • Year and Date
      2016-10-19
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Growth of study of minimally important difference for patient-reported outcomes: bibliographic study2016

    • Author(s)
      Suzukamo Y, Goto Y, Miyazaki K, Naito M, Shimozuma K
    • Organizer
      International Society for Quality of Life Researc
    • Place of Presentation
      Copenhagen
    • Year and Date
      2016-10-19
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Trend of descriptions of palliative care in clinical practice guidelines of cancer before and after the enforcement of Cancer Control Act in Japan: A Content analysis2016

    • Author(s)
      Miyazaki K, Hinata M, Kyoto Study Group on Clinical Practice Guidelines, Nakayama T
    • Organizer
      Guidelines International Network (G-I-N) Conference
    • Place of Presentation
      Philadelphia
    • Year and Date
      2016-09-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] がん薬物療法を行った大腸がんサバイバーの面接調査:病勢コントロールができた症例の質的内容分析2016

    • Author(s)
      宮崎貴久子、堀松高博、松本繁巳、仁科智裕、中山健夫
    • Organizer
      日本緩和医療学会
    • Place of Presentation
      京都
    • Year and Date
      2016-06-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] 患者の価値観とQOL:服薬支援のアートと評価2016

    • Author(s)
      宮崎貴久子
    • Organizer
      日本病院薬剤師会近畿学術大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-01-24
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 質的研究とミクスドメソッド、および公正な研究活動2015

    • Author(s)
      宮崎貴久子
    • Organizer
      日本子ども健康科学界
    • Place of Presentation
      東京
    • Year and Date
      2015-12-10
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 緩和ケアにおけるQOL評価評価研究の生命倫理的課題への一考察2015

    • Author(s)
      宮崎貴久子
    • Organizer
      生命倫理学会
    • Place of Presentation
      千葉
    • Year and Date
      2015-11-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] QOL評価研究の基礎と緩和ケアのQOL研究2015

    • Author(s)
      宮崎貴久子
    • Organizer
      日本在宅医療学会
    • Place of Presentation
      東京
    • Year and Date
      2015-07-20
    • Related Report
      2015 Annual Research Report
  • [Presentation] PRO/QOL-related articles by clinical specialty. The 21st Annual Conference of the International Society for Quality of Life Research2014

    • Author(s)
      Miyazaki K,
    • Organizer
      International Society for Quality of Life Research
    • Place of Presentation
      Berlin
    • Year and Date
      2014-10-15 – 2014-10-18
    • Related Report
      2014 Annual Research Report
  • [Presentation] QOL/PROと診療ガイドライン.シンポジウム-意思決定にいかすQOL/PRO2014

    • Author(s)
      宮崎貴久子
    • Organizer
      日本病院管理学会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-13
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 患者中心医療の実現を目指すQOL/PRO 研究のアプローチ2014

    • Author(s)
      宮崎貴久子
    • Organizer
      日本行動計量学会
    • Place of Presentation
      仙台
    • Year and Date
      2014-09-05
    • Related Report
      2014 Annual Research Report
  • [Presentation] 緩和ケア研究に関する日本発の文献レビュー2014

    • Author(s)
      宮崎貴久子
    • Organizer
      日本緩和医療学会
    • Place of Presentation
      神戸
    • Year and Date
      2014-06-21
    • Related Report
      2014 Annual Research Report
  • [Presentation] Minimally Important Difference (MID):患者視点の医療技術評価の課題 - QOL/PRO研究の最前線2014

    • Author(s)
      宮崎貴久子
    • Organizer
      CSP-HOR
    • Place of Presentation
      東京
    • Year and Date
      2014-06-21
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] QOL評価の臨床的意味:Minimally Important Difference(臨床における最小重要差: MID).「QOL研究から行動医学に向けて」2014

    • Author(s)
      宮崎貴久子
    • Organizer
      第20回日本行動医学会学術総会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] QOL評価研究と行動医学 レスポンスシフトの視点から2014

    • Author(s)
      鈴鴨よしみ
    • Organizer
      第20回日本行動医学会学術総会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] QOL評価研究の歴史と展開2014

    • Author(s)
      下妻晃二郎
    • Organizer
      第20回日本行動医学会学術総会
    • Place of Presentation
      京都
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] QOL/PROと診療ガイドライン2014

    • Author(s)
      宮崎貴久子
    • Organizer
      第52回日本病院管理学会
    • Place of Presentation
      東京
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Relationship between survival time and quality of life in terminal cancer patients receiving palliative care intervention.2013

    • Author(s)
      Miyazaki K, Suzukamo Y, Ohsumi S, Saito M, Ikenaga M, Shimozuma K, Nakayama T.
    • Organizer
      The 20th Annual Conference of the International Society for Quality of Life Research
    • Place of Presentation
      Miami
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cancer Symptoms and Quality of Life2013

    • Author(s)
      Suzukamo Y, Miyazaki K, Shimozuma K, Nakayama T
    • Organizer
      The 20th Annual Conference of the International Society for Quality of Life Research
    • Place of Presentation
      Miami
    • Related Report
      2013 Annual Research Report
  • [Presentation] Minimally Important Difference (MID) in Score on the European Oeganisation for Research and Treatment of Cancer (EORTC)2012

    • Author(s)
      Kikuko Miyazaki
    • Organizer
      International Society for Quality of Life Research
    • Place of Presentation
      ブタペスト、ハンガリー
    • Year and Date
      2012-10-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] Assessment of effects of response shift in palliative care patients using the structural equation modeling approach2012

    • Author(s)
      Yoshimi Suzukamo
    • Organizer
      International Society for Quality of Life Research
    • Place of Presentation
      ブタペスト、ハンガリー
    • Year and Date
      2012-10-24
    • Related Report
      2012 Annual Research Report
  • [Remarks] 京都大学大学院 医学研究科健康情報学 PASQol臨床試験:終末期倦怠感治療のRCT

    • URL

      http://www.healthim.umin.jp/pasqol.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] UMIN-CTR 臨床試験登録情報の閲覧

    • URL

      https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&recptno=R000013915&language=J

    • Related Report
      2016 Annual Research Report
  • [Remarks] QOLに関する全国調査 結果表

    • URL

      http://www.healthim.umin.jp/resarch/QOL.html

    • Related Report
      2016 Annual Research Report
  • [Remarks] 京都大学大学院医学研究科社会健康医学系専攻健康情報学

    • URL

      http://www.healthim.umin.jp/resarch.html

    • Related Report
      2015 Annual Research Report
  • [Remarks] UMIN-CTR 臨床試験登録情報

    • URL

      https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&recptno=R000013915&language=J

    • Related Report
      2015 Annual Research Report
  • [Remarks] 京都大学大学院 医学研究科 社会健康医学系専攻健康情報学

    • URL

      http://www.healthim.umin.jp/resarch.html

    • Related Report
      2014 Annual Research Report
  • [Remarks] UMIN CTR臨床試験登録情報

    • URL

      https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&recptno=R000013915&language=J

    • Related Report
      2014 Annual Research Report
  • [Remarks] QOL/PRO研究会

    • URL

      http://qol_pro.umin.jp/

    • Related Report
      2014 Annual Research Report
  • [Remarks] 京都大学大学院 医学研究科 社会健康医学系専攻

    • URL

      http://www.healthim.umin.jp/

    • Related Report
      2013 Annual Research Report
  • [Remarks] 京都大学教育研究活動データベース

    • URL

      http://kyouindb.iimc.kyoto-u.ac.jp/j/sB2rD

    • Related Report
      2013 Annual Research Report
  • [Remarks] QOL/PRO研究会

    • URL

      http://qol_pro.umin.jp/

    • Related Report
      2013 Annual Research Report
  • [Remarks]

    • URL

      http://www.healthim.umin.jp/

    • Related Report
      2012 Annual Research Report
  • [Remarks]

    • URL

      http://kyouindb.iimc.kyoto-u.ac.jp/i/sB2rD

    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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