| Budget Amount *help |
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2012: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Outline of Final Research Achievements |
This study was conducted in order to make the foundation of mental prevention by clarifying the interaction between occupational stress and genetic/epigenetic factors. 774 volunteers were recruited. As an epigenetic information which relates to depression, we reported the methylation proportions of BDNF gene(Am J Med Genet B 2014) and MTHFR gene(J Neurol Neurol Disord 2015) as possible useful markers. As an epigenetic information which relates to occupational stress, we reported the methylation proportions of TH gene(J Neurol Neurol Disord 2015) as a possible useful marker.
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