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International comparative research for common risk factors of chronic obstructive lung disease and coronary artery atherosclerosis

Research Project

Project/Area Number 24390174
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Public health/Health science
Research InstitutionNational Cardiovascular Center Research Institute

Principal Investigator

Miyamoto Yoshihiro  国立研究開発法人国立循環器病研究センター, 病院, 部長 (10312224)

Co-Investigator(Kenkyū-buntansha) OKAMURA Tomonori  慶應義塾大学, 医学部, 教授 (00324567)
NAKANO Yasutaka  滋賀医科大学, 医学部, 准教授 (00362377)
Project Period (FY) 2012-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2015: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2014: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2013: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2012: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Keywords疫学 / 国際比較研究
Outline of Final Research Achievements

Chronic obstructive pulmonary disease (COPD) is the third largest cause of death in the world. Because of high smoking rates in the middle-aged Japanese, the number of COPD patients rapidly increased in our super aging society. However, in the statistics of 2009, COPD is only 1.3 % of the total cause of death in Japan. Rates of smoking in men in Japan have been twice as high as in men in the US at least for the past 3 decades. If confirmed, elucidating factors responsible for low COPD rate in Japan could lead to its prevention. Then, by comparing the prevalence of COPD between that of Japanese smoking man and that of US people using the urban residents’ cohort study, the Suita study and the Multi-Ethnic Study of Atherosclerosis study. To get the research informed consent from 101 people, we have conducted a survey to 61 people. As an interim report, the prevalence of COPD might be not so lower than US people.

Report

(5 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (11 results)

All 2014 2013 2012 Other

All Int'l Joint Research (1 results) Journal Article (8 results) (of which Peer Reviewed: 8 results,  Open Access: 2 results) Presentation (2 results)

  • [Int'l Joint Research] ピッツバーグ大学/コロンビア大学/アイオワ大学(米国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Clinical predictors of atheroma progression despite optimal glycemic control in early-stage diabetic patients with coronary artery disease: Insight from the DIANA study.2014

    • Author(s)
      Kataoka Y, Yasuda S, Miyamoto Y, Sase K, Kosuge M, Kimura K, Yoshimasa Y, Miyazaki S, investigators Ds.
    • Journal Title

      J Atheroscler Thromb

      Volume: 21(5) Pages: 509-18

    • NAID

      130004444735

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] High-intensity signals in coronary plaques on noncontrast t1-weighted magnetic resonance imaging as a novel determinant of coronary events2014

    • Author(s)
      Noguchi, T. Kawasaki, T.Tanaka, A. Yasuda, S.Goto, Y. Ishihara, M.Nishimura, K. Miyamoto, Y.Node, K. Koga, N.
    • Journal Title

      Journal of the American College of Cardiology

      Volume: 63 Issue: 10 Pages: 989-999

    • DOI

      10.1016/j.jacc.2013.11.034

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Do differences in risk factors explain the lower rates of coronary heart disease in Japanese versus U.S. women?2013

    • Author(s)
      Sekikawa, A. Willcox, B. J.Usui, T. Carr, J. J.Barinas-Mitchell, E. J.Masaki, K. H. Watanabe, M.Tracy, R. P. Bertolet, M. H.Evans, R. W. Nishimura, K.Sutton-Tyrrell, K. Kuller, L. H.Miyamoto, Y.
    • Journal Title

      Journal of Women's Health

      Volume: 22 Issue: 11 Pages: 966-977

    • DOI

      10.1089/jwh.2012.4087

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Alcohol consumption and cardiovascular disease incidence in men with and without hypertension: the Suita study.2013

    • Author(s)
      Higashiyama A, Okamura T Watanabe M, Kokubo Y, Wakabayashi l, Okayama A, Miyamoto Y.
    • Journal Title

      Hypertens Res

      Volume: 36 Issue: 1 Pages: 58-64

    • DOI

      10.1038/hr.2012.133

    • NAID

      10031163286

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Small Dense Low-Density Lipoproteins Cholesterol can Predict Incident Cardiovascular Disease in an Urban Japanese Cohort: The Suita Study2013

    • Author(s)
      Arai, H., Kokubo, Y., Watanabe, M., Sawamura, T., Ito, Y., Minagawa, A., Okamura, T. and Miyamato, Y.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 20 Issue: 2 Pages: 195-203

    • DOI

      10.5551/jat.14936

    • NAID

      130004845433

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Defining Patients at Extremely High Risk for Coronary Artery Disease in Heterozygous Familial Hypercholesterolemia2012

    • Author(s)
      Sugisawa T, Okamura T, Makino H, Watanabe M, Kishimoto I, Miyamoto Y, Iwamoto N, Yamamoto A, Yokoyama S, Harada-Shiba M
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 4 Pages: 369-375

    • DOI

      10.5551/jat.11536

    • NAID

      130004444603

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of diabetes mellitus on outcomes in Japanese patients undergoing coronary artery bypass grafting2012

    • Author(s)
      Minakata K, Bando K, Takanashi S, Konishi H, Miyamoto Y, Ueshima K, Sato t Ueda Y, Okita Y, Masuda l, Okabayashi H, Yaku H, Yasuno S, Muranaka H, Kasahara M, Miyata S, Okamura Y, Nasu M, Tanemoto K, Arinaga K, Hisashi Y Sakata R
    • Journal Title

      Investigators JS

      Volume: 53 Issue: 3 Pages: 275-84

    • DOI

      10.1016/j.jjcc.2011.12.009

    • NAID

      10031187746

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Does High-Sensitivity C-Reactive Protein or Low-Density Lipoprotein Cholesterol Show a Stronger Relationship with the Cardio-Ankle Vascular Index in Healthy Community Dwellers?: the KOBE Study2012

    • Author(s)
      Higashiyama A, Wakabayashi I, Kubota Y, Adachi Y, Hayashibe A, Nishimura K, Sugiyama D, Kadota A, Imano H, Miyamatsu N, Miyamoto Y, Okamura T.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 11 Pages: 1027-1034

    • DOI

      10.5551/jat.13599

    • NAID

      130004444557

    • ISSN
      1340-3478, 1880-3873
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 肥満症診断におけるウエスト周囲長のカットオフ値決定に関するメタ解析2012

    • Author(s)
      宮本恵宏
    • Organizer
      第33回日本肥満学会・シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2012-10-11
    • Related Report
      2012 Annual Research Report
  • [Presentation] 動脈硬化性疾患の臨床研究と都市部疫学研究2012

    • Author(s)
      宮本恵宏
    • Organizer
      第44回日本動脈硬化学会総会・学術集会・シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2012-07-19
    • Related Report
      2012 Annual Research Report

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Published: 2012-04-24   Modified: 2022-01-27  

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