| Project/Area Number |
24390286
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Hideki 福井大学, 高エネルギー医学研究センター, 准教授 (40142377)
ISHIKAWA Hitoshi 筑波大学, 医学医療系, 准教授 (70344918)
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| Co-Investigator(Renkei-kenkyūsha) |
OKUMURA Toshiyuki 筑波大学, 医学医療系, 准教授 (50241815)
MORITAKE Takashi 産業医科大学, 産業生態科学研究所, 准教授 (50450432)
HASHIMOTO Takayuki 北海道大学, 医学研究科, 特任准教授 (60400678)
MIZUMOTO Masashi 筑波大学, 医学医療系, 講師 (20512388)
MATSUMOTO Yoshitaka 筑波大学, 医学医療系, 助教 (70510395)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2014: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2013: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2012: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Keywords | 粒子線治療 / 放射線治療 / 陽子線治療 |
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| Outline of Final Research Achievements |
There is high possibility to increase cure rate of cancer by using new radiation therapy, proton beam therapy and boron neutron capture therapy (BNCT). We performed not only basic research of these two particle therapy, but also clinical studies of chemoproton therapy for esophageal cancer, locally advanced lung cancer, and cholangiocarcinoma. As a result, chemoproton therapy, which was new field of cancer therapy, showed high treatment effect with less toxicity for the heart and lung. We also carried out clinical study of proton for pediatric cancer, and started long term to follow up of 150 patients. For clinical study of BNCT, the treatments were finalized in 4 patients.
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