Development of glycoprotein-biomrkers for biliary tract cancers and establishment of novel diagnostic system using the combination of these biomarkers

• Project/Area Number: 24390323
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 一般
• Research Field: Digestive surgery
• Research Institution: Tokyo Women's Medical University
• Principal Investigator: YAMAMOTO Masakazu 東京女子医科大学, 医学部, 教授 (60220498)
• Co-Investigator(Kenkyū-buntansha): NAKAYAMA Masamiti 東京女子医科大学, 医学部, 講師 (00338980) ; ARIIZUMI Syunichi 東京女子医科大学, 医学部, 講師 (40277158) ; UTSUNOMIYA Hirohuto 和歌山県立医科大学, 中央機器施設, 准教授 (60264876) ; SHODA Junichi 筑波大学, 医学医療系, 教授 (90241827)
• Project Period (FY): 2012-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000); Fiscal Year 2014: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000); Fiscal Year 2013: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2012: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
• Keywords: 胆道癌 / 糖鎖構造解析 / レクチン / 糖蛋白質 / バイオマーカー / 肝内胆管癌 / 糖鎖医学 / 胆道癌モデル

Outline of Final Research Achievements

We have found a biliary tract cancer-specific glycoprotein biomarker, that is named WFA-positive sialyl-MUC1 (WFA-MUC1), and established a high sensitive assay system. In this study, we measured the levels of WFA-MUC1 in the serum from biliary tract cancers and intrahepatic cholangiocarcinoima under the project of multicenter-based clinical trial, and discuss the clinical significance of this biomarker. The serum concentraions of WFA-MUC1 were significantly higher in the cases of biliary tract cancers and intrahepatic cholangiocarcinoma than in those of benign biliary tract diseases and controls. The serum levels were not different in terms of the tumor stage and histology. The ROC analysis revealed that the capability of WFA-MUC1 to distinguish biliary tract cancers from benign diseases was superior to those of CA19-9 and CEA. Determination of WFA-MUC1 in the serum may be useful for the clinical practice of biliary tract cancers and intrahepatic cholangiocarcinoima.

Research Products

• [Journal Article] Total Volume of Moderate-Vigorous Physical Activity a Week is an Important Factor Improving the Pathophysiology of Obesity-Related Liver Disease. (2015)
  • Author(s): Oh S, Tanaka K, Chiaki K, Tsujimoto T, So R, Shida T, Shoda J
  • Journal Title: Hepatology Volume: 61 Pages: 1205-1215
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] FibroScan502の肝脂肪量測定による非アルコール性脂肪性肝疾患の非侵襲的診断法の有用性について. (2015)
  • Author(s): 志田隆史，磯辺智範，呉 世昶，上牧 隆，岡本嘉一，安藤浩樹，正田純一
  • Journal Title: 日本超音波技師学会雑誌 Volume: 40 Pages: 167-173
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Overexpression and Gene Amplification of HER1, HER2 and HER3 in Biliary Tract Carcinomas and the Possibility for Therapy with a HER2-Targeting Antibody Pertuzumab. (2015)
  • Author(s): Kawamoto T, Thomas M, Yamashita-Kashima Y, Shu S, Ishikura N, Ariizumi S, Yamamoto M, Kurosaki K, Shoda J.
  • Journal Title: J Gastroenterrol Volume: 50 Pages: 467-479
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Expression of insulin-like growth factor receptor (IGFR) as a useful biomarker for predicting prognosis in biliary tract cancer patients. (2015)
  • Author(s): Suzuki H, Roa JC, Kawamoto T, Ishige K, Shoda J, Wistuba II, Li D, Thomas MB.
  • Journal Title: Mol & Clin Oncol Volume: 3 Pages: 464-470
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 膵癌に対する術前治療をめぐって Borderline resectable膵癌に対する化学放射線療法を用いた治療戦略 (2014)
  • Author(s): 羽鳥隆, 鈴木修司, 大島奈々, 鈴木隆二, 君島映, 出雲渉, 古川徹, 田原純子, 高山敬子, 清水京子, 白鳥敬子, 三橋紀夫, 山本雅一*
  • Journal Title: 胆と膵 Volume: 35 Pages: 43-47
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 膵癌に対する術前治療をめぐって (2014)
  • Author(s): 羽鳥隆, 鈴木修司, 大島奈々, 鈴木隆二, 君島映, 出雲渉, 古川徹, 田原純子, 高山敬子, 清水京子, 白鳥敬子, 三橋紀夫, 山本雅一*
  • Journal Title: 胆と膵 Volume: 35 Pages: 43-47
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 見直される膵癌診療の新展開 診断における新展開 膵癌鑑別におけるPETの意義と限界 (2014)
  • Author(s): 羽鳥隆, 鈴木修司, 大島奈々, 君島映, 鈴木隆二, 出雲渉, 清水京子, 白鳥敬子, 山本雅一*
  • Journal Title: 臨床外科 Volume: 69 Pages: 17-21
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Safe Transanal Tumor Resection Using a Harmonic Scalpel (2014)
  • Author(s): Inoue Yuji, Ohki Takeshi, Nakagawa Ryosuke, Yamamoto Masakazu
  • Journal Title: International surgery Volume: 99 Pages: 17-22
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Positive glypican-3 expression in early hepatocellular carcinoma predicts recurrence after hepatectomy (2014)
  • Author(s): Chen I-pei†, Ariizumi Shunichi, Nakano Masayuki, Yamamoto Masakazu
  • Journal Title: Journal of Gastroenterology Volume: 49 Pages: 117-125
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] An extended dysfunctional area in the congestive area of the remnant liver after hemi-hepatectomy with middle hepatic vein resection for liver cancers evaluated on the gadoxetic acid disodium-enhanced magnetic resonance imaging (2014)
  • Author(s): Mu Han, Ariizumi Shunichi, Katagiri Satoshi, Egawa Hiroto, Yamamoto Masakazu
  • Journal Title: Journal of Hepato-Biliary-Pancreatic Sciences Volume: 21 Pages: 64-71
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 移植と最先端医療 移植（1）肝臓 成人生体肝移植：術式の変遷と血液型不適合移植の進歩 (2014)
  • Author(s): 尾形哲†, 江川裕人, 山本雅一
  • Journal Title: 東京女子医科大学雑誌 Volume: 84 Pages: 1-8
  • NAID: 110009676511
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 ディベート★消化器・一般手術選ぶのはどっちだ！ 消化器外科手術; テーマ4 肝切除術における肝門部脈管処理一括処理vs個別処理）肝切除術における肝門部脈管処理「一括処理」の立場から (2014)
  • Author(s): 片桐聡†, 山本雅一
  • Journal Title: 臨床外科 Volume: 69 Pages: 171-174
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Degraded DNA may induce discordance of KRAS status between primary colorectal cancer and corresponding liver metastases (2014)
  • Author(s): Kaneko Yuka, Kuramochi Hidekazu, Nakajima Go, Inoue Yuji, Yamamoto Masakazu
  • Journal Title: International journal of clinical oncology Volume: 19 Pages: 113-120
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Multidisciplinary treatments for hepatocellular carcinoma with maor portal vein tumor thrombus (2014)
  • Author(s): Katagiri Satoshi, Yamamoto Masakazu
  • Journal Title: Surgery Today Volume: 44 Pages: 219-226
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 細胞シートを用いたESD後食道再生 (2014)
  • Author(s): 大木岳志, 大和雅之, 岡野光夫, 山本雅一
  • Journal Title: Surgery Frontier Volume: 44 Pages: 49-53
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 普及を目指した他家細胞シート移植による食道再生医療の試み (2014)
  • Author(s): 金井信雄, 大和雅之, 小林慎一朗, 山本雅一, 岡野光夫
  • Journal Title: 最新医学 Volume: 69 Pages: 178-185
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 専門医必修！消化器癌定型手術の標準手技アトラス 肝癌 20.肝区域切除 (2014)
  • Author(s): 片桐聡, 山本雅一
  • Journal Title: 手術 Volume: 68 Pages: 519-524
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 消化器外科におけるチーム医療 食道癌治療におけるチーム医療の現状と展望 (2014)
  • Author(s): 成宮孝祐, 太田正穂, 工藤健司, 佐藤拓也, 白井雄史, 金子由香, 伊藤俊一, 堀部達也, 工藤弦, 菊地剛, 山中昭広, 井手博子, 小谷透, 山本雅一
  • Journal Title: 消化器外科 Volume: 37 Pages: 335-341
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 早く上達する大腸内視鏡挿入法〔部位上達法～これで勝負が決まる勘所〕肝彎曲 (2014)
  • Author(s): 井上雄志, 中川了輔, 上小鶴弘孝, 野口岳春, 山本伸, 前田新介, 大木岳志, 山本雅一
  • Journal Title: 消化器内視鏡 Volume: 26 Pages: 384-388
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 胆道癌として外科切除された鑑別困難病変の検証-画像と病理所見の対比-胆嚢癌と鑑別の困難な胆嚢壁肥厚性病変の臨床病理学的検討 (2014)
  • Author(s): 樋口亮太, 梶山英樹, 谷澤武久, 岡野美々, 太田岳洋, 古川徹, 山本雅一
  • Journal Title: 胆と膵 Volume: 35 Pages: 299-306
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 胸腔鏡補助下憩室切除術を施行した中部食道牽引圧出性憩室の1例 (2014)
  • Author(s): 椎原正尋, 工藤健司, 太田正穂, 成宮孝祐, 白井雄史, 山本雅一
  • Journal Title: 日本臨床外科学会雑誌 Volume: 75 Pages: 662-667
  • NAID: 130004696545
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Phase I clinical trial of multiple-peptide vaccination for patients with advanced biliary tract cancer (2014)
  • Author(s): Aruga Atsushi, Takeshita Nobuhiro, Kotera Yoshihito, Okuyama Ryuji, Matsushita Norimasa, Ota Takehiro, Takeda Kazuyoshi, Yamamoto Masakazu
  • Journal Title: Journal of Translational Medicine Volume: 12 Pages: 61-72
  • NAID: 120007164943
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 樹状細胞がんワクチン療法をめざした脂肪組織由来幹細胞からのiPS細胞の樹立 (2014)
  • Author(s): 松下典正, 小林肇, 有賀淳, 山本雅一
  • Journal Title: 癌と化学療法 Volume: 41 Pages: 467-470
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] VII.膵臓の手術 膵体尾部切除術（D2） (2014)
  • Author(s): 羽鳥隆, 山本雅一
  • Journal Title: 消化器外科 Volume: 37 Pages: 892-896
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] V.肝臓の手術 肝前区域切除術（Glisson一括処理） (2014)
  • Author(s): 片桐聡†, 山本雅一
  • Journal Title: 消化器外科 Volume: 37 Pages: 761-765
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 完全腹腔鏡下肝部分切除を行った肝外発育型巨大肝血管腫の1例 (2014)
  • Author(s): 古屋佳子, 有泉俊一, 高橋豊, 大森亜紀子, 山本伸, 小寺由人, 片桐聡, 江川裕人, 山本雅一
  • Journal Title: 東京女子医科大学雑誌 Volume: 84 Pages: 54-57
  • NAID: 110009770439
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 糖原病Ia型に合併した多発幹細胞腺腫の1例 (2014)
  • Author(s): 植村修一郎, 有泉俊一, 高橋豊, 大森亜紀子, 小寺由人, 片桐聡, 橋本悦子, 中野雅行, 山本雅一
  • Journal Title: 日本消化器病学会雑誌 Volume: 111 Pages: 787-796
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Postoperative dendritic cell vaccine plus activated T-cell transfer improves the survival of patients with invasive hepatocellular carcinoma (2014)
  • Author(s): Koichi Shimizu, Yoshihito Kotera, Nobuhiro Takeshita, Satoshi Katagiri, Shun-ichi Ariizumi, Yutaka Takahashi, Kenji Yoshitoshi, Ken Takasaki, Masakazu Yamamoto
  • Journal Title: Human Vaccines & Immunotherapeutics Volume: 10 Pages: 970-976
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Primary esophageal mucosa-associated lymphoid tissue lymphoma treated by endoscopic submucosal dissection (2014)
  • Author(s): Kudo Kenji, Ota Masaho, Narumiya Kosuke, Shirai Yuji, Ohki Takeshi, Yamamoto Masakazu
  • Journal Title: Digestive Endoscopy Volume: 26 Pages: 478-481
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 膵がん退治の始まり ボーダーラインresectableからresectableへの戦略とその成績 (2014)
  • Author(s): 羽鳥隆, 大島奈々, 出雲渉, 君島映, 古川徹, 白鳥敬子, 前林勝也, 山本雅一*
  • Journal Title: 肝胆膵 Volume: 68 Pages: 881-888
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 よくわかるNDC）NDCへの取り組み 消化器外科③肝胆膵外科 (2014)
  • Author(s): 三浦文彦, 高田忠敬, 山本雅一, 矢永勝彦, 海野倫明
  • Journal Title: 臨床外科 Volume: 67 Pages: 776-778
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Clinical and pathological features of solid pseudopapillary neoplasms of the pancreas at a single institution. (2014)
  • Author(s): SUZUKI Shuji, HATORI Takashi, FURUKAWA Toru, SHIRATORI Keiko, YAMAMOTO MASAKAZU
  • Journal Title: Digestive Surgery Volume: 31 Pages: 143-150
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Efficient Induction of Apoptosis by Week1 Kinase Inhibition in Hepatocellular Carcinoma Cells (2014)
  • Author(s): Kogiso Tomomi, Nagahara Hikaru, Hahimoto Etsuko, Ariizumi Shunichi, Yamamoto Masakazu, Shiratori Keiko
  • Journal Title: PLoS ONE Volume: 9
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 バレット食道腺癌の診断と治療）Barrett食道腺癌の転移形式と術式選択の検討 (2014)
  • Author(s): 成宮孝祐, 太田正穂, 工藤健司, 佐藤拓也, 白井雄史, 井手博子, 大杉治司, 山本雅一*
  • Journal Title: Gastroenterology Volume: 59 Pages: 28-33
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 肝胆膵・術後病態に学ぶ 膵全摘術後に必要な管理方法 (2014)
  • Author(s): 羽鳥隆, 大島奈々, 出雲渉, 君島映, 清水京子, 橋本悦子, 白鳥敬子, 内潟安子, 山本雅一*
  • Journal Title: 肝胆膵 Volume: 69 Pages: 73-78
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Clinicopathological characterization of so-called "cholangiocarcinoma with intraductal papillary growth" with respect to "intraductal papillary neoplasm of bile duct (IPNB)". (2014)
  • Author(s): Nakanuma Y, Sato Y, Ojima H, Kanai Y, Aishima S, Yamamoto M, Ariizumi S, Furukawa T, Hayashi H, Unno M, Ohta T
  • Journal Title: International Journal of Clinical and Experimental Pathology Volume: 7 Pages: 3112-3122
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Clinical relevance of frozen diagnosis of ductal margins in surgery of bile duct cancer. (2014)
  • Author(s): FURUKAWA Toru†, HIGUCHI Ryota, YAMAMOTO Masakazu
  • Journal Title: Journal of Hepato-Biliary-Pancreatic Sciences Volume: 21 Pages: 459-462
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （手術手技）下部早期直腸癌に対する経肛門的腫瘍切除術 (2014)
  • Author(s): 井上雄志, 大木岳志, 上小鶴弘孝, 野口岳春, 中川了輔, 山本雅一
  • Journal Title: 手術 Volume: 68 Pages: 1205-1208
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 肝胆膵癌の血管浸潤をどう治療するか 胆嚢癌の門脈・肝動脈浸潤 (2014)
  • Author(s): 樋口亮太, 谷澤武久, 植村修一郎, 岡野美々, 梶山英樹, 太田岳洋, 古川徹, 新井田達雄, 山本雅一*
  • Journal Title: 臨床外科 Volume: 69 Pages: 948-954
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] indications for portal vein embolization in perihilar cholangicarcinoma (2014)
  • Author(s): Higuchi Ryota†, Yamamoto Masakazu
  • Journal Title: Journal of Hepato-Biliary-Pancreatic Sciences Volume: 21 Pages: 542-549
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 いわゆる「早期胆嚢癌」に関する問題点を整理する）早期胆嚢癌とICPNおよび粘液性形質との関連 (2014)
  • Author(s): 古川徹†, 樋口亮太, 山本雅一
  • Journal Title: 胆と膵 Volume: 35 Pages: 835-839
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 腸閉塞に基づく敗血症性ショックに対する大量輸液が一因となったabdominal compartment syndromeに緊急開腹およびイレウス解除術を施行して救命し得た1例 (2014)
  • Author(s): 出雲渉, 樋口亮太, 福田聡史, 方山真朱, 宮崎裕也, 佐藤庸子, 小谷透, 山本雅一
  • Journal Title: 日本腹部救急医学会雑誌 Volume: 36 Pages: 1175-1179
  • NAID: 130004890908
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Development of a Novel In Vivo Cancer Model Using Cell Sheet Engineering (2014)
  • Author(s): Suzuki Ryuji, Aruga Atsushi*, Kobayasi Hajime, Yamato Masayuki, Yamamoto Masakazu
  • Journal Title: Anticancer research Volume: 34 Pages: 4747-4754
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Diagnotic accuracy of transient hepatic attenuation differances on computed tomography scans for acute cholangitis in patients with malignant disase (2014)
  • Author(s): Sugishita Toshiya, Higuchi Ryota, Morita Satoru, Yamamoto Masakazu, Ota Takehiro
  • Journal Title: Journal of Hepato-Biliary-Pancreatic Sciences Volume: 21 Pages: 669-675
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 消化管の再生医療 食道再生医療の現状と展望 (2014)
  • Author(s): 大木岳志, 大和雅之, 太田正穂, 高木亮, 近藤誠, 金井信雄, 岡野光夫, 山本雅一*
  • Journal Title: G.I.Research Volume: 22 Pages: 411-417
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 胆嚢癌手術のすべて－腹腔鏡下から拡大手術まで－）肝切除＋膵頭十二指腸切除 (2014)
  • Author(s): 樋口亮太, 山本雅一
  • Journal Title: 手術 Volume: 68 Pages: 1471-1476
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 消化器外科手術ピットフォールとリカバリーショット）II.各論 5.肝 a)肝切除術中出血が多いときどうするか (2014)
  • Author(s): 有泉俊一, 山本雅一
  • Journal Title: 外科 Volume: 76 Pages: 1416-1419
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 肝細胞腺腫,FNHと周辺病変の新しい考え方）外科的アプローチ (2014)
  • Author(s): 有泉俊一, 山本雅一
  • Journal Title: 肝胆膵 Volume: 69 Pages: 781-788
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] （特集 肝細胞腺腫、FNHと周辺病変の新しい考え方）肝細胞腺腫の疫学と背景因子：欧米との比較 (2014)
  • Author(s): 杉谷雅彦†, 羽野寛, 八尾隆史, 森下由紀雄, 神田浩明, 松本光司, 林星舟, 有泉俊一, 山本雅一, 中野雅行
  • Journal Title: 肝胆膵 Volume: 69 Pages: 691-694
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 特集 肝切除術－基本手技と工夫－ Glisson一括処理による系統的肝切除 (2014)
  • Author(s): 片桐聡, 山本雅一, 有泉俊一, 小寺由人, 高橋豊*
  • Journal Title: 手術 Volume: 68 Pages: 1667-1672
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] "Surgical Approaches to Advanced Gallbladder Cancer A 40-Year Single-Institution Study of Prognotic Factors and Resectability" (2014)
  • Author(s): Higuchi Ryota, Ota Takehiro, Araida Tatsuo, Kajiyama Hideki, Yazawa Takehisa, Furukawa Toru, Yoshikawa Tatsuya, Takasaki Ken, Yamamoto Masakazu*
  • Journal Title: Annals of surgical oncology Volume: 21 Pages: 4308-4316
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Integrated Analysis of Whole Genome and Transcriptome Sequencing Reveals Diverse Transcriptomic Aberrations Driven by Somatic Genomic Chages in Liver Cancers (2014)
  • Author(s): Shiraishi Yuichi†, Yamamoto Masakazu, Nakagawa Hidewaki
  • Journal Title: PLOS ONE Volume: 9
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 茨城県における肝細胞癌疫学調査． (2014)
  • Author(s): 佐野直樹，田村孝史，福永 潔，高野恵輔，山岸良匡，正田純一，相川達也，大河内信弘
  • Journal Title: 肝臓 Volume: 55 Pages: 771-773
  • NAID: 130004897340
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Changes in diffusion tensor imaging (DTI) eigenvalues of skeletal muscle due to hybrid exercise training Magnetic Resonance Imaging. (2014)
  • Author(s): Okamoto Y, Kemp GJ, Isobe T, Sato E, Hirano Y, Shoda J, Minami M.
  • Journal Title: Magnetic Resonance Imaging Volume: 32 Pages: 1297-1300
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Abdominal obesity: causal factor or simply a symptom of obesity-related healyh risk. (2014)
  • Author(s): Oh S, Tanaka K, Noh J, So R, Tsujimoto T, Sasai H, Kim M, Shoda J.
  • Journal Title: Diabetes, Metab Syn & Obesity Volume: 7 Pages: 289-296
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Acceleration training for management of non-alcoholic fatty liver disease: a pilot study. (2014)
  • Author(s): Oh S, Shida T, Onozuka T, Maruyama T, Eguchi K, Isobe T, Okamoto Y, Someya N, Tanaka K, Tozawa A, Arai E, Shoda J.
  • Journal Title: Ther Clin Risk Manag Volume: 10 Pages: 925-936
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Interaction of Muc4 and ErbB2 in a transgenic mouse model of gallbladder carcinoma: potential pathobiological implications. (2014)
  • Author(s): Miyahara N, Ishida H, Ueda T, Kawamoto T, Akimoto Y, Kawakami H, DiGiovanni J, Kiguchi K, Irimura T, Shoda J.
  • Journal Title: Oncol Rep Volume: 32 Pages: 1796-1802
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Regular Exercise Coupled to Diet Regimen Accelerates Reduction of Hepatic Steatosis and Associated Pathological Conditions in Non-Alcoholic Fatty Liver Disease. (2014)
  • Author(s): Oh S, Tanaka K, Tsujimoto T, So R, Eto M, Shoda J.
  • Journal Title: Metabolic Syndrome & Related Disorders Volume: 12 Pages: 290-298
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Therapeutic effect of hybrid training of voluntary and electrical muscle contractions on middle-aged obese women with NAFLD: a pilot study. (2014)
  • Author(s): Oh S, Shida T, Ikeda A, Maruyama T, Eguchi K, Isobe T, Okamoto Y, Arai E, Shiba N, Shoda J.
  • Journal Title: Ther Clin Risk Manag Volume: 11 Pages: 371-380
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Interleukin-4 receptor α-based hybrid peptide effectively induces antitumor activity in biliary tract cancer cells. (2014)
  • Author(s): Seto K, Shoda J, Horibe T, Warabi E, Kohno M, Yanagawa T, Bukawa H, Nakanuma Y, Kawakami Y.
  • Journal Title: Int J Hepatol Volume: 10 Pages: 1155-1161
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Peroxidoxin I plays a ptotective role against UVA irradiation through reduction of oxidative stress. (2014)
  • Author(s): Ito T, Kimura S, Seto K, Warabi E, Kawauchi Y, Shoda J, Tabuchi K, Yamagata K, Hasegawa S, Bukawa H, Ishii T, Yanagawa T.
  • Journal Title: J Dermatol Sci Volume: 74 Pages: 9-17
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Expression of N-acetylglucosaminyltransferase V in the subserosal layer correlates with postsurgical survival of pathological tumor stage 2 carcinoma of the gallbladder. (2014)
  • Author(s): Onuki, K., Sugiyama, H., Ishige, K., Kawamoto, T., Ota, T., Ariizumi, S., Yamato, M., Kadota, S., Takeuchi, K., Ishikawa, A., Onodera, M., Onizawa, K., Yamamoto, M., Miyoshi, E., Shoda, J.
  • Journal Title: J Gastroenterol Volume: 49 Pages: 702-714
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Interleukin-4 receptor α-based hybrid peptide effectively induces antitumor activity in biliary tract cancer cells (2014)
  • Author(s): Seto K, Shoda J, Horibe T, Warabi E, Kohno M, Yanagawa T, Bukawa H, Nakanuma Y, Kawakami K
  • Journal Title: Int J Hepatol Volume: 未定 Pages: 584650-584650
  • DOI: 10.1155/2014/584650
  • Peer Reviewed / Open Access
• [Journal Article] Expression of N-acetylglucosaminyltransferase V in the subserosal layer correlates with postsurgical survival of pathological tumor stage 2 carcinoma of the gallbladder. (2013)
  • Author(s): Onuki K, Sugiyama H, Ishige K, Kawamoto T, Ota T, Ariizumi S, Yamato M, Kadota S, Takeuchi K, Ishikawa A, Onodera M, Onizawa K, Yamamoto M, Miyoshi E, Shoda J
  • Journal Title: J Gastroenterol Volume: 49 Pages: 702-714
  • Peer Reviewed
• [Journal Article] Negative expression of N-acetylglucosaminyltransferase V in oral squamous cell carcinoma correlates with poor prognosis. (2013)
  • Author(s): Seto K, Uchida F, Baba O, Miyoshi E,et.al.
  • Journal Title: Springerplus Volume: 2 Issue: 1 Pages: 657-657
  • DOI: 10.1186/2193-1801-2-657
  • Peer Reviewed
• [Journal Article] Interleukin-4 receptor α-based hybrid peptide effectively induces antitumor activity in head and neck squamous cell carcinoma (2013)
  • Author(s): Seto K, Shoda J, Horibe T, Warabi E, Ishige K, Yamagata K, Kohno M, Yanagawa T, Bukawa H, Kawakami K
  • Journal Title: Oncology Report Volume: 29 Pages: 2147-2153
  • Peer Reviewed
• [Journal Article] Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet (2013)
  • Author(s): Okada K, Warabi E, Sugimoto H, Horie M, Gotoh N, Tokushige K, Hashimoto E, Utsunomiya H, Takahashi H, Ishii T, Yamamoto M, Shoda J
  • Journal Title: J Gastroenterol Volume: 48 Pages: 620-632
  • NAID: 10031177013
  • Peer Reviewed
• [Journal Article] Glycoproteomics-based cancer marker discovery adopting dual enrichment with Wisteria floribunda agglutinin for high specific glyco-diagnosis of cholangiocarcinoma. (2013)
  • Author(s): Matsuda A, Kuno A, Matsuzaki H, Kawamoto T, Shinkai T, Nakanuma Y, Yamamoto M, Ohkohchi N, Ikehara Y, Shoda J, Hirabayashi J, Narimatsu H
  • Journal Title: J Proteomics Volume: 85 Pages: 1-11
  • DOI: 10.1016/j.jprot.2013.04.017
  • Peer Reviewed
• [Journal Article] Impact of Hepatectomy for Huge Solotary Hepatocellular Carcinoma (2013)
  • Author(s): Ariizumi S, Kotera Y, Takahashi Y, Katagiri S, Yamamoto M
  • Journal Title: J Surg Oncol Volume: 107
  • Peer Reviewed
• [Journal Article] Novel virtual hepatectomy is useful is for evaluation of the portal territory for anatomical sectionectomy,segmentsctomy,and hemihepatectomy (2013)
  • Author(s): Ariizumi S, Takahashi Y, Kotera Y, Omori A, Yoneda G, Mu H, Katagiri S, Egawa H, Yamamoto M
  • Journal Title: JHBPS Volume: 20 Pages: 396-402
  • Peer Reviewed
• [Journal Article] Disease recurrence plays a minor role as a cause for retransplantation after living-donor liver transplantation for primary biliary cirrhosis:A multicenter studt in Japan (2013)
  • Author(s): Egawa H, Nakanura Y, Maehara Y, Uemoto S, Eguchi S, Sato Y, Shirabe K, Takatsuki M, Mori A, Yamamoto M, Tsubouchi H
  • Journal Title: Hepatology Res Volume: 43 Pages: 502-507
  • Peer Reviewed
• [Journal Article] Lymphatic vessel endothelial hyaluronan receptor-1 is a novel prognostic indicator for human hepatocellular caecinoma (2013)
  • Author(s): KItagawa K, Nakajima G, Kuramochi H, Ariizumi S, Yamamoto M
  • Journal Title: Mol Clin Oncol Volume: 1 Pages: 1039-1048
  • Peer Reviewed
• [Journal Article] Depth of submucosal Invasion in the sessile and superficial types of submucosal Invasive clorectal carcinoma:objective versus subjective measurement (2013)
  • Author(s): Inoue Y, Ohki T, Nakagawa R, Yamamoto M
  • Journal Title: Hepato-gastroenterology Volume: 60 Pages: 1916-1921
  • Peer Reviewed
• [Journal Article] Phase I clinical trial of a peptide vaccine combined with tegafur-uracil plus leucovorin for treatment of advanced or recurrent colorectal cancer (2013)
  • Author(s): Matsushita N, Aruga A, Inoue Y, Kotera Y, Terada K, Yamamto M
  • Journal Title: Oncology Reports Volume: 29 Pages: 951-951
  • Peer Reviewed
• [Journal Article] The discrete nature and distinguishing molecular features of pancreatic intraductal tubulopapillary neoplasms and intraductal papillary mucinous neoplasms of the gastric type, pyloric gland variant. (2013)
  • Author(s): Yamauchi H, Kuboki Y, Hatori T, Yamamoto M, Shimizu K, Shiratori K, Shibata N, Shimizu M, Furukawa T
  • Journal Title: Jf Pathology Volume: 213 Pages: 335-341
  • Peer Reviewed
• [Journal Article] Prevention of Esophageal Stricture After Endoscopic Submucosal Dissection Using Tissue-Engineered Cell Sheets (2012)
  • Author(s): Ohki T, Yamato M, Ota M, Takagi R, Murakami D, Kondo M, Sasaki R, Namiki H, Okano T, Yamamoto M.
  • Journal Title: Gastroenterology Volume: 143(3) Issue: 3 Pages: 582-588
  • DOI: 10.1053/j.gastro.2012.04.050
  • Peer Reviewed
• [Journal Article] Right hepatectomy using Glissonean pedicle transection method with anterior (2012)
  • Author(s): Katagiri S, et al.
  • Journal Title: J Hepatobiliary Pancreat Sci Volume: 19 Issue: 1 Pages: 25-29
  • DOI: 10.1007/s00534-011-0445-y
  • Peer Reviewed
• [Journal Article] Glissonean pedicle transection method for liver surgery (with video). (2012)
  • Author(s): Masakazu Yamamoto
  • Journal Title: J Hepatobiliary Pancreat Sci Volume: 19 Issue: 1 Pages: 3-8
  • DOI: 10.1007/s00534-011-0443-0
  • NAID: 10030241560
  • Peer Reviewed
• [Presentation] （特別講演3）肝外科手術のへのこだわり 先達からの継承 (2014)
  • Author(s): 山本雅一
  • Organizer: 第76回日本臨床外科学会総会
  • Place of Presentation: 郡山市民文化センター（福島県郡山市）
  • Year and Date: 2014-11-20
• [Presentation] 肝細胞腺腫の新たな診断法と限局性結節性過形成の再診断 (2014)
  • Author(s): 有泉俊一, 中野雅行, 山本雅一
  • Organizer: 第19回日本外科病理学会学術集会
  • Place of Presentation: 沖縄県医師会館（沖縄県島尻郡）
  • Year and Date: 2014-11-14
• [Presentation] （ワークショップ2 解剖的知見を基にした肝胆膵外科手術の新展開）肝臓外科解剖を基にした肝門部グリソン鞘一括切除術 (2014)
  • Author(s): 山本雅一
  • Organizer: 第18回臨床解剖研究会 第2回アジア臨床解剖学会
  • Place of Presentation: 東京医科歯科大学 M&Dタワー（東京都文京区）
  • Year and Date: 2014-11-08
• [Presentation] (Symposium5 Inovation in Surgery)HCC and Perihilar cholangiocarcinoma (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: The 39th Biennial World Congress of the International College of Surgeons in Conjunctions With 20th Annual Scientific Meeting of Indonesian Surgeons Association
  • Place of Presentation: Bali,Indonesia
  • Year and Date: 2014-10-20
• [Presentation] Surgical Outcome of Patients with Hepatocellular Carcinoma Showing High Intensity in the Hepatobiliary Phase of Gadoxetic Acid Disodium-Enhanced Magnetic Resonance Images (2014)
  • Author(s): Ariizumi Shunichi
  • Organizer: The 39th Biennial World Congress of the International College of Surgeons in Conjunctions With 20th Annual Scientific Meeting of Indonesian Surgeons Association
  • Place of Presentation: Bali,Indonesia
  • Year and Date: 2014-10-20
• [Presentation] 肝切除周術期管理の工夫 (2014)
  • Author(s): 山本雅一
  • Organizer: 栗橋地域連携講演会
  • Place of Presentation: 済生会栗橋病院（埼玉県久喜市）
  • Year and Date: 2014-08-26
• [Presentation] Anterior Approach to Right Hepatectomy with Caudate Lobectomy for Perihilar Cholangiocarcinoma (2014)
  • Author(s): Yamamoto Masakazu, Higuchi Ryota
  • Organizer: 39th RCST Annual Scientific Congress
  • Place of Presentation: Pattaya, Thailand
  • Year and Date: 2014-07-10
• [Presentation] Progress in surgical Oncology:resent Surgical Treatment for Hepatocellular Carcinoma (2014)
  • Author(s): Yamamoto Masakazu, Ariizumi Shunici, Katagiri Satoshi
  • Organizer: 39th RCST Annual Scientific Congress
  • Place of Presentation: Pattaya, Thailand
  • Year and Date: 2014-07-10
• [Presentation] Repeat Hepatrctomy for Patients with Intrahepatic Recurrence of Hepatocellular Carcinoma (2014)
  • Author(s): Ariizumi Shunichi, Katagiri Satoshi, Kotera Yoshihito, Takahashi Yutaka, Egawa Hiroto, Yamamoto Masakazu
  • Organizer: 4th International Kyoto Liver Cancer Symposium
  • Place of Presentation: Kyoto, Japan
  • Year and Date: 2014-07-07
• [Presentation] 肝切除周術期管理の工夫 (2014)
  • Author(s): 山本雅一
  • Organizer: 第2回広島周術期フォーラム
  • Place of Presentation: ANAクラウンプラザホテル広島（広島県広島市）
  • Year and Date: 2014-07-02
• [Presentation] (Experimental Laboratory-Personalised Training on Live Tissue)Laparoscopic hepatic pedicle dissection (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: International Advanced Course"New Perspectives in Hepatobiliary and Pancreatic Surgery"
  • Place of Presentation: Strasbourg, France
  • Year and Date: 2014-06-19
• [Presentation] (Experimental Laboratory-Personalised Training on Live Tissue)T-Tube placement (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: International Advanced Course"New Perspectives in Hepatobiliary and Pancreatic Surgery"
  • Place of Presentation: Strasbourg, France
  • Year and Date: 2014-06-19
• [Presentation] (Pre-recorded operative demonstration)Anterior segmentectomy (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: International Advanced Course"New Perspectives in Hepatobiliary and Pancreatic Surgery"
  • Place of Presentation: Strasbourg, France
  • Year and Date: 2014-06-19
• [Presentation] Liver surgical anatony for Glissonean pedicle approach (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: International Advanced Course"New Perspectives in Hepatobiliary and Pancreatic Surgery"
  • Place of Presentation: Strasbourg, France
  • Year and Date: 2014-06-19
• [Presentation] Management of perioperative complication:bleeding and bile leak (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: International Advanced Course"New Perspectives in Hepatobiliary and Pancreatic Surgery"
  • Place of Presentation: Strasbourg, France
  • Year and Date: 2014-06-19
• [Presentation] （シンポジウム1（胆） 進行胆道癌に対す集学的治療）術後補助療法は進行肝内胆管癌の予後を改善する (2014)
  • Author(s): 有泉俊一, 小寺由人, 高橋豊, 山下信吾, 大森亜紀子, 片桐聡, 樋口亮太, 太田岳洋, 江川裕人, 山本雅一
  • Organizer: 第26回日本肝胆膵外科学会学術集会
  • Place of Presentation: 和歌山県民文化会館（和歌山県和歌山市）
  • Year and Date: 2014-06-11
• [Presentation] （シンポジウム1 早期肝細胞癌の基礎・診断・治療・予後）Glypican3陽性の早期肝細胞癌は二次発癌が高率である (2014)
  • Author(s): 有泉俊一, ChenI-pei, 片桐聡, 小寺由人, 高橋豊, 大森亜紀子, 山下信吾, 尾形哲, 江川裕人, 中野雅行, 山本雅一
  • Organizer: 第50回日本肝癌研究会
  • Place of Presentation: 国立京都国際会館（京都府京都市）
  • Year and Date: 2014-06-05
• [Presentation] （パネルディスカッション6 混合型肝癌の病理と診断）細胆管細胞癌の切除成績は混合型肝癌とは異なる (2014)
  • Author(s): 有泉俊一, 片桐聡, 小寺由人, 高橋豊, 大森亜紀子, 山下信吾, 尾形哲, 江川裕人, 中野雅行, 斎藤明子, 山本雅一
  • Organizer: 第50回日本肝癌研究会
  • Place of Presentation: 国立京都国際会館（京都府京都市）
  • Year and Date: 2014-06-05
• [Presentation] Master-class liver operations (2014)
  • Author(s): Yamamoto Masakazu, Katagiri Satoshi, Chinburen Jigjidsuren
  • Organizer: Master class on "The trestment of HCC"
  • Place of Presentation: Shimkent, Kazakhstan
  • Year and Date: 2014-05-01
• [Presentation] Master-class liver operations 2 (2014)
  • Author(s): Yamamoto Masakazu, Katagiri Satoshi, Chinburen Jigjidsuren
  • Organizer: Master class on "The trestment of HCC"
  • Place of Presentation: Shimkent, Kazakhstan
  • Year and Date: 2014-05-01
• [Presentation] Progress in surgical oncology:Resent surgical treatment for liver cancer (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: Master class on "The trestment of HCC"
  • Place of Presentation: Shimkent, Kazakhstan
  • Year and Date: 2014-05-01
• [Presentation] What's new in surgery for Perihilar cholangiocarcinoma (2014)
  • Author(s): Yamamoto Masakazu
  • Organizer: Master class on "The trestment of HCC"
  • Place of Presentation: Shimkent, Kazakhstan
  • Year and Date: 2014-05-01
• [Presentation] 多血性早期肝細胞癌の1例 (2014)
  • Author(s): 有泉俊一, 高橋豊, 大森亜紀子, 小寺由人, 尾形哲, 山下信吾, 片桐聡, 山本雅一, 中野雅行
  • Organizer: 第49回肝癌症例検討会
  • Place of Presentation: 秋葉原コンベンションホール（東京都千代田区）
  • Year and Date: 2014-04-19
• [Presentation] （パネルディスカッション5 肝細胞癌治療のガイドライン・コンセンサス・アルゴリズムの検証）肝細胞癌のStage分類（T因子）を加えた新しい治療アルゴリズム (2014)
  • Author(s): 有泉俊一, 小寺由人, 高橋豊, 大森亜紀子, 山下信吾, 山本伸, 尾形哲, 片桐聡, 江川裕人, 山本雅一
  • Organizer: 第114回日本外科学会定期学術集会
  • Place of Presentation: 国立京都国際会館（京都府京都市）
  • Year and Date: 2014-04-03
• [Presentation] 胆道疾患 - 肥満・生活習慣病と胆道疾患 (2013)
  • Author(s): 正田純一
  • Organizer: 第49回日本肝臓学会総会 教育講演
  • Place of Presentation: 東京
  • Invited
• [Presentation] Surgical managrment of Perihilar Cholangiocarcinoma (2013)
  • Author(s): Yamamoto M, Higuchi R
  • Organizer: International College of Suegeons Asia Pacific Federation Congress 2013 in Commemoration of 60tu Anniversary of ICS Thailand Section
  • Place of Presentation: Bankok
  • Invited
• [Presentation] An Evaluation of the Single Incision Clip Less Laparoscopic Cholecystectomy (2013)
  • Author(s): Yamamoto M
  • Organizer: International College of Suegeons Asia Pacific Federation Congress 2013 in Commemoration of 60tu Anniversary of ICS Thailand Section
  • Place of Presentation: Bankok
  • Invited
• [Presentation] 肝内胆管癌の新規糖蛋白質マーカーの開発 (2013)
  • Author(s): 小貫建一郎，樋口亮太，谷澤武久，梶山英樹，川本徹，山本雅一，中沼安二，大河内信弘, 松田厚志，久野 敦，成松 久，正田純一
  • Organizer: 第49回胆道学会
  • Place of Presentation: 千葉
• [Presentation] 胆石の種類と成因(日本胆道学会認定指導医養成講座) (2012)
  • Author(s): 正田純一
  • Organizer: 第48回日本胆道学会学術集会
  • Place of Presentation: 東京(招待講演)
  • Year and Date: 2012-09-20
• [Book] 胆汁酸とその分画 新・検査値のみかた (2015)
  • Author(s): 正田純一
  • Total Pages: 2
  • Publisher: 中外医学社
• [Book] ACS Multimedia Atlas of Surgery:Liver Surgery Volume (2014)
  • Author(s): Taksaki Ken, Katagiri Satoshi, Ariizumi Shunichi, Kotera Yoshihito, Takahashi Yutaka, Yamamoto Masakazu
  • Total Pages: 8
  • Publisher: Cine-Med
• [Book] Carcinoma of the Gallbladder The Current Scenario (2014)
  • Author(s): Higuchi Ryota, Yamamoto Masakazu
  • Total Pages: 9
  • Publisher: India
• [Book] Gastrointestinal Endoscopy Clinics of North America (2014)
  • Author(s): Ohki Takeshi, Yamato Masayuki, Okano Teruo, Yamamoto Masakazu
  • Total Pages: 9
  • Publisher: Elsevier
• [Book] これで納得！画像で見ぬく消化器疾患 胆道・膵臓 (2014)
  • Author(s): 高山敬子, 白鳥敬子, 片桐聡, 山本雅一
  • Total Pages: 2
  • Publisher: 医学出版
• [Book] 膵癌治療up-to-date 2015 (2014)
  • Author(s): 羽鳥隆, 土井愛美, 大島奈々, 君島映, 田原純子, 高山敬子, 清水京子, 白鳥敬子, 山本雅一
  • Total Pages: 6
  • Publisher: 医学図書出版
• [Book] 高齢者対象の運動教室における心拍数については，どのような配慮が必要でしょうか． (2014)
  • Author(s): 横山有里，正田純一
  • Total Pages: 2
  • Publisher: メデイカルフィットネス研究会 田中喜代次編集
• [Book] 透析患者にも運動療法は有効なのでしょうか．お勧めの運動はあるのでしょうか． (2014)
  • Author(s): 横山有里，正田純一
  • Total Pages: 2
  • Publisher: メデイカルフィットネス研究会 田中喜代次編集
• [Book] Epidemiology and Pathogenesis of Hepatocellular Carcinoma. In: Hepatocellular Carcinoma. (2014)
  • Author(s): Shoda, J., Ohokohchi, N.
  • Total Pages: 23
  • Publisher: NOVA Science Publishers
• [Book] 肝内胆管癌の新規バイオマーカー (2014)
  • Author(s): 正田純一，松田厚志，久野 敦，池原 譲，成松 久，大河内信弘，山本雅一，中沼安二
  • Total Pages: 3
  • Publisher: 文光堂
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  • Author(s): 正田純一
  • Total Pages: 5
  • Publisher: 中外医学社
• [Book] 肝癌診療Q&A (2013)
  • Author(s): 有泉俊一、山本雅一
  • Total Pages: 5
  • Publisher: 中外医学社
• [Book] Horizons in Cancer Research. Volume 48 (2013)
  • Author(s): Shoda J, Yamamoto M, et al.
  • Total Pages: 33
  • Publisher: NOVA Publishers
• [Patent(Industrial Property Rights)] 肝内胆管がんの検出・判別方法 (2012)
  • Inventor(s): 正田純一, 他
  • Industrial Property Rights Holder: 筑波大学
  • Filing Date: 2012-04-01
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