Central and peripheral control of ingestion function
| Project/Area Number |
24390431
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthetic dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
INOUE Makoto 新潟大学, 医歯学系, 教授 (00303131)
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| Co-Investigator(Kenkyū-buntansha) |
HORI Kazuhiro 新潟大学, 医歯学系, 准教授 (70379080)
TANIGUCHI Hiroshige 新潟大学, 医歯学総合病院, 講師 (80529636)
TSUJIMURA Takanori 新潟大学, 医歯学系, 助教 (00548935)
NAKAMURA Yuki 新潟大学, 医歯学系, 助教 (70452779)
MAGARA Jin 新潟大学, 医歯学総合病院, 助教 (90452060)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2014: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2013: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2012: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
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| Keywords | 咀嚼 / 嚥下 / 歯科 / リハビリテーション / 動物 |
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| Outline of Final Research Achievements |
From human and animal studies, we successfully clarified the followings. 1) Initiation of reflex swallowing is not affected by oral inputs but by chewing behavior or activation of chewing central pattern generator. 2) Motor pattern of swallowing is not affected by conditioning stimulation such as peripheral stimulation. 3) Because there is a positive correlation between effect of central inputs and peripheral inputs on the initiation of swallow, inter-individual variation of initiation of swallow is dependent on the excitability of neural activity in the lower brain stem. 4) repetitive pharyngeal stimulation shortly inhibits the excitability involved in the swallowing center but facilitates that involved in voluntary swallow in the long term.
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Report
(4 results)
Research Products
(36 results)
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[Presentation] Effect of carbonated water on swallowing performance2015
Author(s)
Kanda C, Nakamura Y, Hayashi H, Takeishi R, Tsujimura T, Shinoda Y, Kametani N, Okamoto T, Inoue M
Organizer
The Dysphagia Research Society 23rd Annual Meeting
Place of Presentation
The Westin La Paloma Resort & Spa, Chicago, USA
Year and Date
2015-03-12 – 2015-03-14
Related Report
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[Presentation] 炭酸水がもたらす嚥下の変調2014
Author(s)
神田知佳,中村由紀,林 宏和,竹石龍右,篠田有希,亀谷典弘,岡本武久,井上 誠
Organizer
日本顎口腔機能学会第53回学術大会
Place of Presentation
日本大学松戸歯学部，松戸
Year and Date
2014-10-04 – 2014-10-05
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