• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Investigation on neurodegenerative effect of 1-bromopropane using new biomarkers

Research Project

Project/Area Number 24406018
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section海外学術
Research Field Hygiene
Research InstitutionTokyo University of Science (2014)
Nagoya University (2012-2013)

Principal Investigator

ICHIHARA Gaku  東京理科大学, 薬学部, 教授 (90252238)

Co-Investigator(Kenkyū-buntansha) WAKAI Kenji  名古屋大学, 医学系研究科, 教授 (50270989)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2014: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2013: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2012: ¥7,540,000 (Direct Cost: ¥5,800,000、Indirect Cost: ¥1,740,000)
Keywordsバイオマーカー / ブロモプロパン / 量反応関係 / 神経毒性 / 運動 / 振動覚 / 伝道速度
Outline of Final Research Achievements

Protein adduct in globin formed by exposure to 1-bromopropane was quantified in 25 workers in a factory. The level of S-propyl cysteine in globin showed significant and negative association with the number of leucocyte. S-propyl cysteine might be useful as a biomarker for 1-bromopropane exposure.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (135 results)

All 2015 2014 2013 2012 Other

All Journal Article (28 results) (of which Peer Reviewed: 26 results,  Open Access: 4 results) Presentation (105 results) (of which Invited: 2 results) Book (2 results)

  • [Journal Article] Copper oxide nanoparticles reduce vasculogenesis in transgenic zebrafish through down-regulation of VEGF expression and induction of apoptosis.2015

    • Author(s)
      Chang J, Ichihara G, Shimada Y, Tada-Oikawa S, Kuroyanagi J, Zhang B, Suzuki Y, Sehsah R, Kato M, Tanaka T, Ichihara S.
    • Journal Title

      J Nanosci Nanotech

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hippocampal phosphoproteomics of F344 rats exposed to 1-bromopropane.2015

    • Author(s)
      Huang Z, Ichihara S, Oikawa S, Chang J, Zhang L, Hu S, Huang H, Ichihara G.
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 282 Issue: 2 Pages: 151-160

    • DOI

      10.1016/j.taap.2014.10.016

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Zn(II) released from zinc oxide nano/micro particles suppresses vasculogenesis in human endothelial colony-forming cells2015

    • Author(s)
      Saeko Tada-Oikawa, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Wenting Wu,
    • Journal Title

      Toxicology Reports

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time course of blood parameters in printing workers with cholangiocarcinoma2014

    • Author(s)
      Kumagai S, Kurumatani N, Arimoto A, Ichihara G
    • Journal Title

      Journal of Occupational Health

      Volume: 56 Pages: 279-284

    • NAID

      130004694135

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Trends in asbestos and non-asbestos fibre concentrations in the lung tissues of Japanese patients with mesothelioma.2014

    • Author(s)
      Sakai K, Hisanaga N, Shibata E, Kamijima M, Ichihara G, Takeuchi Y, Nakajima T.
    • Journal Title

      Ann Occup Hyg

      Volume: 58 Pages: 103-120

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dispersion method for safety research on manufactured nanomaterials.2014

    • Author(s)
      Wu W, Ichihara G, Suzuki Y, Izuoka K, Oikawa-Tada S, Chang J, Sakai K, Miyazawa K, Porter D, Castranova V, Kawaguchi M, Ichihara S.
    • Journal Title

      Ind Health

      Volume: 52 Pages: 54-65

    • NAID

      130004483598

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat2014

    • Author(s)
      Chang J, Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Aoki C, Yamada Y, Ichihara G, Kato M, Ichihara S
    • Journal Title

      Diabetol Metab Syndr

      Volume: 6(1) Issue: 1 Pages: 8-8

    • DOI

      10.1186/1758-5996-6-8

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of Nanomaterials on Cardiovascular System -Analysis of in Vitro and Animal Experiments.2014

    • Author(s)
      Ichihara S, Tada-Oikawa S, Suzuki Y, Wu W, Ichihara G.
    • Journal Title

      Trans Mater Res Soc Jpn

      Volume: 印刷中

    • NAID

      130005004364

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Zinc oxide nanoparticles induce migration and adhesion of monocytes to endothelial cells and accelerate foam cell formation.2014

    • Author(s)
      Suzuki Y, Tada-Oikawa S, Ichihara G, Yabata M, Izuoka K, Suzuki M, Sakai K, Ichihara S.
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: in press Issue: 1 Pages: 16-25

    • DOI

      10.1016/j.taap.2014.04.010

    • Related Report
      2014 Annual Research Report 2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synergistic effect of bolus exposure to zinc oxide nanoparticles on bleomycin-induced secretion of pro-fibrotic cytokines without lasting fibrotic changes in murine lungs.2014

    • Author(s)
      Wu W, Ichihara G, Hashimoto N, Hasegawa Y, Hayashi Y, Tada-Oikawa S, Suzuki Y, Chang J, Kato M, D’Alessandro-Gabazza CN, Gabazza EC, Ichihara S.
    • Journal Title

      Int J Mol Sci

      Volume: 16 Pages: 660-676

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Time course of blood parameters in printing workers with cholangiocarcinoma.2014

    • Author(s)
      Kumagai S, Kurumatani N, Arimoto A, Ichihara G
    • Journal Title

      Journal of Occupational Health

      Volume: in press

    • NAID

      130004694135

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Copper oxide nanoparticles reduce vasculogenesis in transgenic zebrafish through down-regulation of VEGF expression and induction of apoptosis.2014

    • Author(s)
      Chang J, Ichihara G, Shimada Y, Tada-Oikawa S, Kuroyanagi J, Zhang B, Suzuki Y, Sehasah R, Kato M, Tanaka T, Ichihara S
    • Journal Title

      Journal of Nanoscience and Nanotechnology

      Volume: in press

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane2013

    • Author(s)
      Kumagai S, Ichihara G 他
    • Journal Title

      Occup Environ Med

      Volume: (印刷中) Issue: 7 Pages: 508-510

    • DOI

      10.1136/oemed-2012-101246

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of exposure to 1-bromopropane on astrocytes and oligodendrocytes in rat brain.2013

    • Author(s)
      Mohideen SS, Ichihara S, Subramanian K, Huang Z, Naito H, Kitoh J, Ichihara G
    • Journal Title

      J Occup Health

      Volume: 55 Pages: 29-38

    • NAID

      10031139891

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Serial changes in adipocytokines and cardiac function in a rat model of the metabolic syndrome.2013

    • Author(s)
      Yamaguchi T, Kitamori K, Ichihara G, Suzuki Y, Ochiai M, Yamada Y, Tada-Oikawa S, Tsuchikura S, Yamori Y, Ichihara S.
    • Journal Title

      Clin Exp Pharmacol Physiol

      Volume: 40 Issue: 7 Pages: 443-448

    • DOI

      10.1111/1440-1681.12107

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced constitutive invasion activity in human nontumorigenic keratinocytes exposed to a low level of barium for a long time.2013

    • Author(s)
      Thang ND, Yajima I, Ohnuma S, Ohgami N, Kumasaka MY, Ichihara G. Kato M.
    • Journal Title

      Environmental Toxicology

      Volume: - Issue: 2 Pages: 161-167

    • DOI

      10.1002/tox.21881

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comparison of Barium and Arsenic Concentrations in Well Drinking Water and in Human Body Samples and a Novel Remediation System for These Elements in Well Drinking Water.2013

    • Author(s)
      Kato M, Kumasaka MY, Ohnuma S, Furuta A, Kato Y, Shekhar HU, Kojima M, Koike Y, Dinh Thang N, Ohgami N, Ly TB, Jia X, Yetti H, Naito H, Ichihara G, Yajima I.
    • Journal Title

      PLoS One

      Volume: -

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Rats with metabolic syndrome resist the protective effects of N-acetyl l-cystein against impaired spermatogenesis induced by high-phosphorus/zinc-free diet.2013

    • Author(s)
      Suzuki Y, Ichihara G, Sahabudeen SM, Kato A, Yamaguchi T, Imanaka-Yoshida K, Yoshida T, Yamada Y, Ichihara S.
    • Journal Title

      Exp Toxicol Pathol

      Volume: 65 Issue: 7-8 Pages: 1173-1182

    • DOI

      10.1016/j.etp.2013.05.009

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis.2013

    • Author(s)
      Ichihara S, Yamamoto K, Asano H, Nakatochi M, Sukegawa M, Ichihara G, Izawa H, Hirashiki A, Takatsu F, Umeda H, Iwase M, Inagaki H, Hirayama H, Sone T, Nishigaki K, Minatoguchi S, Cho MC, Jang Y, Kim HS, Yokota M. 他10名
    • Journal Title

      Circ Cardiovasc Genet

      Volume: 6 Issue: 6 Pages: 569-578

    • DOI

      10.1161/circgenetics.111.000027

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 1-Bromopropane曝露による中毒性神経障害の一例2013

    • Author(s)
      寒川真、塩山実章、鈴木秀和、上田昌美、岡伸幸、市原学、三井良之、楠進
    • Journal Title

      産業医学ジャーナル

      Volume: 36 Pages: 16-21

    • Related Report
      2013 Annual Research Report
  • [Journal Article] Effects of sub-acute and sub-chronic inhalation of 1-bromopropane on neurogenesis in adult rats.2012

    • Author(s)
      L Zhang, T Nagai, K Yamada, D Ihi, S Ichihara K Subramanian.
    • Journal Title

      Toxicology

      Volume: 304C Pages: 76-82

    • DOI

      10.1016/j.tox.2012.12.009

    • Related Report
      2013 Annual Research Report 2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neurotoxicity of 1-bromopropane: Evidence from animal experiments and human studies2012

    • Author(s)
      Ichihara G, 他5名
    • Journal Title

      Journal of Advanced Research

      Volume: 3 (2) Issue: 2 Pages: 91-98

    • DOI

      10.1016/j.jare.2011.04.005

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Occupational exposure to neurotoxic substances in Asian countries - Challenges and approaches2012

    • Author(s)
      Meyer-Baron M, Ichihara G他3名
    • Journal Title

      Neurotoxicology

      Volume: 33(4) Issue: 4 Pages: 853-861

    • DOI

      10.1016/j.neuro.2011.12.012

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Proteomic identification of carbonylated proteins in F344 rat hippocampus after 1-bromopropane exposure2012

    • Author(s)
      Huang Z, Ichihara G他6名
    • Journal Title

      Toxi col Appl Pharmacol.

      Volume: 263(1) Issue: 1 Pages: 44-52

    • DOI

      10.1016/j.taap.2012.05.021

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A case of severe neurotoxicity associated with exposure to 1-bromopropane, an alternative to ozone-depleting or global-warming solvents2012

    • Author(s)
      Samukawa M, Ichihara G, Oka N, Kusunoki S.
    • Journal Title

      Arch Intern Med.

      Volume: 172(16) Pages: 1257-1260

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat.2012

    • Author(s)
      Chang J, Oikawa S, Ichihara G, Nanpei Y, Hotta Y, Yamada Y, Tada-Oikawa S, Iwahashi H, Kitagawa E, Takeuchi I, Yuda M, Ichihara S.
    • Journal Title

      Nutr Metab (Lond).

      Volume: 9(1) Issue: 1 Pages: 87-87

    • DOI

      10.1186/1743-7075-9-87

    • NAID

      120006667439

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of Exposure to 1-Bromopropane on Astrocytes and Oligodendrocytes in Rat Brain2012

    • Author(s)
      Mohideen SS, Ichihara S, Subramanian K, Huang Z, Naito H, Kitoh J, Ichihara G.
    • Journal Title

      J Occup Health.

      Volume: 55 Pages: 29-38

    • NAID

      10031139891

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Exposure to 1-bromopropane induces microglial changes and oxidative stress in the rat cerebellum.2012

    • Author(s)
      Subramanian K, Mohideen SS, Suzumura A, Asai N, Murakumo Y, Takahashi M, Jin S, Zhang L, Huang Z, Ichihara S, Kitoh J, Ichihara G.
    • Journal Title

      Toxicology.

      Volume: 302(1) Issue: 1 Pages: 18-24

    • DOI

      10.1016/j.tox.2012.07.006

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 1- ブロモプロパン神経毒性のマウスモデルの確立2015

    • Author(s)
      宗才、黄晋彦、エドウィンガーナ―、張霊逸、 張堯、市原佐保子、市原学
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸サンボーホール他 神戸市
    • Year and Date
      2015-03-28
    • Related Report
      2014 Annual Research Report
  • [Presentation] 1-ブロモプロパン神経毒性のマウスモデルの確立2015

    • Author(s)
      宗才、黄晋彦、エドウィンガーナ―、張霊逸、 張堯、櫻井敏博、加藤昌志、市原佐保子、市原学
    • Organizer
      第85回日本衛生学会学術総会
    • Place of Presentation
      和歌山県民文化センター 和歌山市
    • Year and Date
      2015-03-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Animal models for cholangiocarcinoma induced by chemicals associated with the offset printing2015

    • Author(s)
      Lingyi Zhang, Shinji Kumagai, Shinya Toyokuni, Hisao Naito, Sahoko Ichihara, Gaku Ichihara
    • Organizer
      SOT 54th Annual Meeting
    • Place of Presentation
      San Diego California, USA
    • Year and Date
      2015-03-22 – 2015-03-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Administration of 1-aminobenzotriazole reduces adverse effects of 1-bromopropane on epididymal sperm2015

    • Author(s)
      Chin-Yen Huang, Edwin Garner, Cai Zong, Lingyi Zhang, Xiao Zhang, Sahoko Ichihara, Gaku Ichihara,
    • Organizer
      SOT 54th Annual Meeting
    • Place of Presentation
      San Diego California, USA
    • Year and Date
      2015-03-22 – 2015-03-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] Establishment of mouse model for neurotoxicity of 1-bromopropane, an alternative to ozone-depleting solvents2015

    • Author(s)
      Cai Zong, Edwin Garner, Chin-Yen Huang, Lingyi Zhang, Xiao Zhang, Shinya Toyokuni, Sahoko Ichihara, Gaku Ichihara,
    • Organizer
      SOT 54th Annual Meeting
    • Place of Presentation
      San Diego California, USA
    • Year and Date
      2015-03-22 – 2015-03-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 1-ブロモプロパン神経毒性のマウスモデルの確立2015

    • Author(s)
      宗 才 、黄 晋彦、エドウィン ガーナ― 、張 霊逸 、張 堯 、加藤昌志、市原佐保子、市原 学
    • Organizer
      第14回分子予防環境医学研究会
    • Place of Presentation
      大阪市立大学医学部 大阪市
    • Year and Date
      2015-02-13 – 2015-02-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 単球の血管内皮細胞への接着能に及ぼす酸化チタンナノ粒子の影響2015

    • Author(s)
      鈴木悠加、市原 学、及川(多田)佐枝子、村上理彦、出岡 淑、市原佐保子
    • Organizer
      第14回分子予防環境医学研究会
    • Place of Presentation
      大阪市立大学医学部 大阪市
    • Year and Date
      2015-02-13 – 2015-02-14
    • Related Report
      2014 Annual Research Report
  • [Presentation] 1-ブロモプロパン神経毒性のマウスモデルの確立2014

    • Author(s)
      宗才、黄晋彦、エドウィンガーナ―、張霊逸、張堯、市原佐保子、市原学
    • Organizer
      第42回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      松本市中央公民館 松本市
    • Year and Date
      2014-10-25 – 2014-10-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 2-ジクロロプロパンの発がん性 発症機序から2014

    • Author(s)
      市原 学
    • Organizer
      第42回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      松本市中央公民館 松本市
    • Year and Date
      2014-10-25 – 2014-10-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] 工業ナノマテリアルの生態影響機序解明のための動物モデル2014

    • Author(s)
      市原学、呉文亭、Radwa Sehsah、Esteban C Gabazza、伊東健、山本雅之、市原佐保子
    • Organizer
      日本薬学会環境・衛生部会学術年会 フォーラム2014:衛生薬学・環境トキシコロジー
    • Place of Presentation
      つくば国際会議場、つくば市
    • Year and Date
      2014-09-19 – 2014-09-20
    • Related Report
      2014 Annual Research Report
  • [Presentation] Biodistribution and effects of SiO2 NPs in mice and in a transgenic model of Zebra fish (Danio rerio)2014

    • Author(s)
      Sandra Vranic, Sahoko Ichihara, Yasuhito Shimada, Toshio Tanaka, Wenting Wu, Sonja Boland, Lang Tran and Gaku Ichihara
    • Organizer
      IUMRS-ICA2014
    • Place of Presentation
      福岡大学 福岡市
    • Year and Date
      2014-08-24 – 2014-08-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] Animal models for mechanistic studies on biological effects of manufactured nanomaterials2014

    • Author(s)
      市原学
    • Organizer
      第3回工業用ナノマテリアルのリスク管理研究会
    • Place of Presentation
      NIMS 並木地区 つくば市
    • Year and Date
      2014-08-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] Synergistic effect of exposure to zinc oxide nanoparticle on inflammatory response to bleomycin-induced pulmonary fibrosis in mice2014

    • Author(s)
      Wenting Wu, Gaku Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Yasuhiko Hayashi, Masashi Kato, Saeko Tada-Oikawa, Yuka Suzuki, Jie Chang1, Corina N. D'Alessandro-Gabazza, Esteban C. Gabazza, Sahoko Ichihara
    • Organizer
      第41回日本毒性学会
    • Place of Presentation
      神戸コンベンションセンター 神戸市
    • Year and Date
      2014-07-02 – 2014-07-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] Involvement of Nrf-2 in zinc oxide nanoparticles-induced pulmonary inflammation2014

    • Author(s)
      Radwa Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Ken Ito, Masayuki Yamamoto, Emily Kamel, Gaku Ichihara
    • Organizer
      第41回日本毒性学会
    • Place of Presentation
      神戸コンベンションセンター 神戸市
    • Year and Date
      2014-07-02 – 2014-07-04
    • Related Report
      2014 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2014

    • Author(s)
      呉文亭、市原学、及川(多田)佐枝子、鈴木悠加、常杰、橋本直純、長谷川好規、ガバザ コリナ、ガバザ エステバン、市原 佐保子
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 酸化亜鉛ナノ粒子が誘導する肺炎症におけるNrf2の関与2014

    • Author(s)
      セサ ラドワ、呉文亭、市原 佐保子、橋本直純、長谷川好規、伊東健、山本雅之、カメル エミリ、市原学
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] マウスと遺伝子改変ゼブラフィッシュにおけるシリカナノ粒子の生態分布と影響2014

    • Author(s)
      ブラニッチ サンドラ、市原 佐保子、島田康人、田中利男、呉文亭、ボーランド ソニア、トラン ラン、市原学
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] ラット脳脊髄液中甲状腺ホルモンレベルの変化への1BP曝露の影響2014

    • Author(s)
      張霊逸、宗才、鯉渕典之、市原 佐保子、藤田博美、内藤久雄、加藤昌志、市原学
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 単層、二層カーボンナノチューブによる動脈硬化症への影響とその作用機序の検討2014

    • Author(s)
      鈴木悠加、市原学、宗才、及川(多田)佐枝子、出岡淑、市原佐保子
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 酸化亜鉛ナノ粒子の血管内皮前駆細胞に対する影響2014

    • Author(s)
      及川(多田)佐枝子、市原学、鈴木悠加、出岡淑、三島隆、市原佐保子
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 1ーアミノベンゾトライアゾールの投与は1ーブロモプロパン曝露による肝障害を減弱2014

    • Author(s)
      宗才、黄晋彦、エドウィンガーナ―、張霊逸、 張堯、、市原学
    • Organizer
      第84日本衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-26 – 2014-05-27
    • Related Report
      2014 Annual Research Report
  • [Presentation] 中国酸化チタン粒子取扱工場労働者に対する心肺機能を中心とした調査研究2014

    • Author(s)
      市原佐保子、李衛華、尾村誠一、藤谷雄二、平工雄介、久永直見、丁訓誠、小林隆弘、市原学
    • Organizer
      第87回日本産業衛生学会
    • Place of Presentation
      岡山コンベンションセンター 岡山市
    • Year and Date
      2014-05-21 – 2014-05-24
    • Related Report
      2014 Annual Research Report
  • [Presentation] Biodistribution and effects of SiO2 NPs in mice and in a transgenic model of Zebra fish (Danio rerio)2014

    • Author(s)
      Sandra Vranic, Sahoko Ichihara, Yasuhito Shimada, Toshio Tanaka, Wenting Wu, Sonja Boland, LangTran, Gaku Ichihara
    • Organizer
      NANOTOX 2014, 7th International Nanotoxicology Congress
    • Place of Presentation
      トルコ、アンタルヤ
    • Year and Date
      2014-04-23 – 2014-04-26
    • Related Report
      2014 Annual Research Report
  • [Presentation] ラット脳脊髄液中甲状腺ホルモンレベルの変化への1BP曝露の影響2014

    • Author(s)
      張 霊逸,宗 才,鯉淵典之,市原佐保子,藤田博美,常 杰,黄 晋彦,内藤久雄,市原 学
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of pharyngeal aspiration exposure to zinc oxide nanoparticles on pulmonary fibrosis induced by bleomycin in mice2014

    • Author(s)
      Wenting Wu, Gaku Ichihara, Saeko Tada-Oikawa, Yuka Suzuki, Jie Chang, Naozumi Hashimoto, Yoshinori Hasegawa, Corina Gabazza, Esteban Gabazza, Sahoko Ichihara
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 単層、二層カーボンナノチューブによるアテローム性動脈硬化症への影響とその作用機序の検討2014

    • Author(s)
      鈴木悠加,市原 学,宗 才,及川(多田)佐枝子,出岡 淑,市原佐保子
    • Organizer
      第13回分子予防環境医学研究会
    • Place of Presentation
      和歌山県民文化会館、和歌山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of Exposure to 1-Bromopropane on the Level of Thyroid Hormone in Cerebrospinal Fluid of Rats.2014

    • Author(s)
      L. Zhang, C. Zong1, N. Koibuchi, S. Ichihara, H. Fujita, J. Chang, J. Huang, H. Naito, M. Kato, G. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Fenofibrate Reduces Cardiac Fibrosis Due to the Reduction of the DNA Binding Activity of the Hypoxia-Inducible Factor-1/Aryl Hydrocarbon Receptor Nuclear Translocator Complex.2014

    • Author(s)
      S. Ichihara, Y. Suzuki, S. Tada-Oikawa and G. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc Oxide Nanoparticles Induce Cytotoxicity in Human Endothelial Colony-Forming Cells2014

    • Author(s)
      Y. Suzuki, S. Tada-Oikawa1, G. Ichihara, K. Izuoka and S. Ichihara.
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Effects of Pharyngeal Aspiration-Exposure to Zinc Oxide Nanoparticles on Pulmonary Fibrosis Induced Bleomycin in Mice.2014

    • Author(s)
      W. Wu, G. Ichihara, S. Tada-Oikawa, Y. Suzuki, J. Chang,N. Hashimoto, Y. Hasegawa, D. W. Porter, V. Castranova, C. Gabazza, E. Gabazza, S. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Effects of Metal Oxide Nanoparticles on Angiogenesis in Transgenic Zebrafish2014

    • Author(s)
      J. Chang, G. Ichihara, Y. Shimada, S. Tada-Oikawa, Y. Suzuki, R. Sehsah, M. Kato, T. Tanaka, S. Ichihara
    • Organizer
      The 53rd Annual Meeting of the Society of Toxicology
    • Place of Presentation
      Phoenix Convention Center, AZ, USA
    • Related Report
      2013 Annual Research Report
  • [Presentation] オフセット印刷労働者に多発した胆管癌の原因物質解明のための動物実験2013

    • Author(s)
      市原学
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ラットにおける1-BPの亜急性と亜慢性吸入暴露によって神経新生への影響2013

    • Author(s)
      張霊逸、永井拓、山田清文、衣斐大祐、市原佐保子、サブラマニアンカビアラサン、黄振烈、モヒデインサハブディン、内藤久雄、市原学
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたナノ酸化金属の血管新生に対する影響の検討2013

    • Author(s)
      常杰、市原学、及川(多田)佐枝子、島田康人、田中利男、市原佐保子
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉文亭、 市原学、及川(多田)佐枝子、 鈴木悠加、常杰、 橋本直純、 長谷川好規、ガバザコリナ、 ガバザエステバン、市原佐保子
    • Organizer
      第86回日本産業衛生学会
    • Place of Presentation
      ひめぎんホール、愛媛・松山市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が,ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉文亭、 市原学、及川(多田)佐枝子、 鈴木悠加、常杰、 橋本直純、 長谷川好規、
    • Organizer
      第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ国際会議場、千葉市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたナノ酸化金属の血管新生に対する影響の検討2013

    • Author(s)
      常 杰,市原 学,及川(多田) 佐枝子,島田 康人,田中 利男,市原 佐保子
    • Organizer
      第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ国際会議場、千葉市
    • Related Report
      2013 Annual Research Report
  • [Presentation] 工業ナノマテリアルの職業暴露評価における課題2013

    • Author(s)
      市原 学,小林 隆弘,藤谷 雄二,尾村 誠一,市原 佐保子
    • Organizer
      シンポジウム「ナノマテリアルの評価手法開発における今後の課題」 第40回日本毒性学会学術年会
    • Place of Presentation
      幕張メッセ国際会議場、千葉市
    • Related Report
      2013 Annual Research Report
  • [Presentation] The Effect of Pharyngeal Aspiration Exposureto Zinc Oxide Nanoparticles on Pulmonary Fibrosis Induced by Bleomycin in Mice2013

    • Author(s)
      Wu W,Gaku Ichihara,Saeko tada-Oikawa,Yuka Suzuki,Jie Chang,Naozumi Hashimoto,Yoshimori Hasegawa,Corina Gabazza,Esteban Gabazza and Sahoko Ichihara
    • Organizer
      the XIII International Congress of Toxicology
    • Place of Presentation
      Coex,Seoul,Korea
    • Related Report
      2013 Annual Research Report
  • [Presentation] Occupational and environmental health in nanotechnology2013

    • Author(s)
      Ichihara G
    • Organizer
      Symposium "Ecological and Health Impact of Nanomaterials and Nanotechnology" in the 7th International Conference on Materials for Advanced Technologies(ICMAT2013)
    • Place of Presentation
      Suntec,Singapore
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] The effects of pharyngeal aspiration exposure to zinc oxide nanoparticles on pulmonary fibrosis induced by bleomycin in mice2013

    • Author(s)
      Wenting Wu,Gaku Ichihara,Saeko tada-Oikawa,Yuka Suzuki,Jie Chang,Naozumi Hashimoto,Yoshimori Hasegawa,Corina Gabazza,Esteban Gabazza and Sahoko Ichihara
    • Organizer
      日本産業衛生学会 第41回 産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      大阪市立大学医学部校舎、大阪市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of exposure to 1-bromopropane on the level of thyroid hormone in cerebrospinal fluid of rats2013

    • Author(s)
      張 霊逸、宗 才、鯉淵 典之、市原 佐保子、藤田 博美、常 杰、黄 晋彦、内藤 久雄、市原 学
    • Organizer
      日本産業衛生学会 第41回 産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      大阪市立大学医学部校舎、大阪市
    • Related Report
      2013 Annual Research Report
  • [Presentation] NanOEHS Overview2013

    • Author(s)
      Gaku Ichihara, Yoshinori Hasegawa
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Critical factors in multi-walled carbon nanotubes for mesothelial carcinogenesis2013

    • Author(s)
      Shinya Toyokuni, Hirotaka Nagai, Yasumasa Okazaki, Shan Hwu Chew, Shinya Akatsuka, Li Jiang, Gaku Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc oxide particles induced migration and adhesion of monocytes and increased macrophage cholesterol2013

    • Author(s)
      Yuka Suzuki, Saeko Tada-Oikawa, Gaku Ichihara, Kiyoshi Sakai, Masayuki Yabata, Kiyora Izuoka, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects on Respiratory and Cardiovascular Systems in Workers Handling Titanium Dioxide Particles2013

    • Author(s)
      Sahoko Ichihara, Weihua Li, Seiichi Omura, Yuji Fujitani, Ying Liu, Qiangyi Wang, Yusuke Hiraku, Naomi Hisanaga, Xuncheng Ding, Takahiro Kobayashi, Gaku Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials2013

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kun’ichi Miyazawa, Dale Porter, Vincent Castranova, Masami Kawaguchi , Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] The effects of exposure to zinc oxide nanoparticles on bleomycin-induced pulmonary fibrosis in mice2013

    • Author(s)
      Wenting Wu, Gaku Ichihara, Saeko Tada-Oikawa, Yuka Suzuki, Jie Chang, Naozumi Hashimoto, Yoshinori Hasegawa, Corina Gabazza, Esteban Gabazza, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] The effects of metal oxide nanoparticles on angiogenesis in transgenic zebrafish2013

    • Author(s)
      Jie Chang, Gaku Ichihara, Saeko Tada-Oikawa, Kiyora Izuoka, Toshio Tanaka, Yasuhito Shimada, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Involvement of Nrf-2 in ZnO NP-induced pulmonary inflammation2013

    • Author(s)
      Radwa Ibrahim Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Ken Ito, Masayuki Yamamoto, Emily Kamel, Gaku Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Single-wall or double-wall carbon nanotubes induce atherosclerosis progression in ApoE null mice2013

    • Author(s)
      Yuka Suzuki, Gaku Ichihara, Yuka Suzuki , Kiyora Izuoka, Kiyoshi Sakai, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Zinc oxide nanoparticles induce cytotoxicity and apoptosis in human endothelial colony-forming cells2013

    • Author(s)
      Saeko Tada-Oikawa, Gaku Ichihara, Yuka Suzuki , Kiyora Izuoka, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cytotoxicity induced by nano-sized TiO2 in human monocytic leukemia cells and colon cancer cells2013

    • Author(s)
      Saeko Tada-Oikawa, Gaku Ichihara, Yuka Suzuki , Kiyora Izuoka, Sahoko Ichihara
    • Organizer
      The 6th International Symposium on Nanotechnology, Occupational and Environmental Health; NanOEH6(第6回国際ナノテクノロジー労働環境衛生シンポジウム)
    • Place of Presentation
      名古屋国際会議場、名古屋市
    • Related Report
      2013 Annual Research Report
  • [Presentation] Cardiovascular Effects of Manufactured Nanomaterials2013

    • Author(s)
      S. Ichihara, Y. Suzuki, S. Tada-Oikawa, K. Izuoka, C. Zong, G. Ichihara
    • Organizer
      第23回日本MRS年次大会
    • Place of Presentation
      横浜開港記念会館、横浜市
    • Related Report
      2013 Annual Research Report
  • [Presentation] ラット脳脊髄液中甲状腺ホルモンレベルの変化への1BP曝露の影響2013

    • Author(s)
      張 霊逸、宗 才、鯉淵 典之、市原 佐保子、藤田 博美、常 杰、黄 晋彦、内藤 久雄、市原 学
    • Organizer
      環境ホルモン学会第16回研究発表会
    • Place of Presentation
      東京大学山上会館、東京都文京区
    • Related Report
      2013 Annual Research Report
  • [Presentation] Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane on neurogenesis in adult rats2013

    • Author(s)
      Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito, Gaku Ichihara
    • Organizer
      Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane on neurogenesis in adult rats
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉〓〓, 市原学, 及川(多田)佐枝子, 鈴木悠加, 常杰, 橋本直純, 長谷川好規, ガバザコリナ, ガバザエステバン, 市原佐保子
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノ酸化亜鉛による単球遊走作用とマクロファージのコレステロール取り込み作用への影響2013

    • Author(s)
      鈴木悠加, 及川(多田)佐枝子, 出岡淑, 市原学, 市原佐保子
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] The effects of metal oxide nanoparticles on angiogenesis in transgenic zebrafish2013

    • Author(s)
      常杰, 市原学, 及川(多田)佐枝子, 島田康人, 田中利男, 市原佐保子
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 全ゲノム罹患同胞対連鎖解析による新規若年発症心筋梗塞感受性遺伝子の同定2013

    • Author(s)
      市原佐保子, 山本健, 市原学, 井ノ上逸朗, 横田充弘
    • Organizer
      第12回分子予防環境医学研究会大会
    • Place of Presentation
      つくばサイエンス・インフォメーションセンター(つくば市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Neurotoxicity of 1-bromopropane : Review and perspective2013

    • Author(s)
      Gaku Ichihara
    • Organizer
      Workshop on 1-bromopropane toxicity in Shanghai
    • Place of Presentation
      上海、Fudan University School of Public Health(中国)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of Short- and Long-Term Exposure to 1-Bromopropane on Neurogenesis in Adult Rats2013

    • Author(s)
      L. Zhang, T. Nagai, K. Yamada, D.Ibi, S. Ichihara, K. Subramanian, Z. Huang, S. Sheik Mohideen, H. Naito, and G. Ichihara.
    • Organizer
      The 52th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      SanAntonio, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] Zinc Oxide Particles Induced Migration of Monocytes and Increased Macrophage Cholesterol Uptake2013

    • Author(s)
      Y. Suzuki, S. Tada-Oikawa, G. Ichihara, and S. Ichihara.
    • Organizer
      The 52th Annual Meeting of the Society of Toxicology
    • Place of Presentation
      SanAntonio, USA
    • Related Report
      2012 Annual Research Report
  • [Presentation] 全ゲノム罹患同胞対連鎖解析による新規若年発症心筋梗塞感受性遺伝子の同定2013

    • Author(s)
      市原佐保子、山本健、浅野展行、中杤昌弘、市原学、松原達昭、井ノ上逸朗、横田充弘
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノ酸化亜鉛によるマクロファージの変性LDL取り込み作用への影響2013

    • Author(s)
      及川(多田)佐枝子、鈴木悠加、出岡淑、市原学、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノ酸化亜鉛による血管内皮障害への影響2013

    • Author(s)
      鈴木悠加、及川(多田)佐枝子、出岡淑、市原学、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノ酸化亜鉛が、ブレオマイシンによって誘導されるマウスの肺線維症に与える影響2013

    • Author(s)
      呉〓〓、市原学、及川(多田)佐枝子、鈴木悠加、常杰、橋本直純、長谷川好規、ガバザコリナ、ガバザエステバン、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ゼブラフィッシュを用いたナノ酸化金属の血管新生に対する影響の検討2013

    • Author(s)
      常杰、市原学、及川(多田)佐枝子、出岡淑、島田康人、田中利男、市原佐保子
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 1BP亜急性および慢性吸入曝露によるラット脳での神経新生への影響2013

    • Author(s)
      張霊逸,永井拓,山田清文,衣斐大祐,市原佐保子,スブラマニアンカビアラサン,黄振烈,シェイクモヒデイーン サハブデイン,内藤久雄,市原学
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(金沢大学 鶴間・宝町キャンパス)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 工業ナノマテリアルのリスク評価と労働環境衛生学2013

    • Author(s)
      市原学
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(横浜市)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of sub-acute and sub-chronic inhalation exposure to 1-bromopropane on neurogenesis in adult rats2012

    • Author(s)
      Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito, Gaku Ichihara
    • Organizer
      日本産業衛生学会 産業神経・行動学研究会 第24回研究会
    • Place of Presentation
      東京女子医科大学医学部中央校舎5階(東京)
    • Year and Date
      2012-12-02
    • Related Report
      2012 Annual Research Report
  • [Presentation] 中皮腫患者の肺内石綿・非石綿繊維量とその表面積2012

    • Author(s)
      酒井潔、久永直見、柴田英治、上島通浩、内藤久雄、市原学、那須民江
    • Organizer
      日本産業衛生学会平成24年度東海地方会
    • Place of Presentation
      じゅうろくプラザ(岐阜市)
    • Year and Date
      2012-11-03
    • Related Report
      2012 Annual Research Report
  • [Presentation] 建設業従事者における石綿曝露職歴、胸膜肥厚斑、肺内石綿・非石綿濃度の関係2012

    • Author(s)
      久永直見、酒井潔、柴田英治、鈴木隆佳、内藤久雄、上島通浩、市原学
    • Organizer
      日本産業衛生学会平成24年度東海地方会
    • Place of Presentation
      じゅうろくプラザ(岐阜市)
    • Year and Date
      2012-11-03
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Sahoko Ichihara
    • Organizer
      Workshop on the risk management of engineered nanomaterials(工業用ナノマテリアルのリスク管理研究会)
    • Place of Presentation
      NIMS(つくば市)
    • Year and Date
      2012-09-27
    • Related Report
      2012 Annual Research Report
  • [Presentation] 工業ナノマテリアルの安全性と労働環境衛生学2012

    • Author(s)
      市原学
    • Organizer
      化学物質・環境規制ワークショップ第一期2012
    • Place of Presentation
      大田区産業プラザ(東京・蒲田)(招待講演)
    • Year and Date
      2012-08-29
    • Related Report
      2012 Annual Research Report
  • [Presentation] ラット脳内モノアミンレベルと海馬神経栄養因子の発現への1-ブロモプロパン曝露の影響2012

    • Author(s)
      張霊逸, 永井拓, 山田清文, 市原佐保子, スブラマニアンカビアラサン, 黄振烈, シェイクモヒディーンサハブディーン, 内藤久雄, 市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 中皮腫患者の肺内石綿の濃度とその繊維サイズ2012

    • Author(s)
      酒井潔、久永直見、柴田英治、上島通浩、市原学、那須民江
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 1-ブロモプロパンはF344ラットの海馬においてTriosephosphate Isomeraseのカルボニル化とAdvanced Glycation End-Productsを増加させる2012

    • Author(s)
      黄振烈、市原佐保子、及川伸二、常杰、張霊逸、Subramanian Kaviarasan、Sheik Mohideen Sahabudeen、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 1-ブロモプロパン曝露のラット小脳におけるグリア、ミエリンに対する影響2012

    • Author(s)
      Sheik Mohideen Sahabudeen、市原佐、Subramanian Kaviarasan、黄振烈、鬼頭純三、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 工業ナノマテリアル安全性研究のための分散法の検討2012

    • Author(s)
      呉文亭、市原佐保子、常杰、及川(多田)佐枝子、太田有香、矢端将行、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 二酸化チタンナノ粒子による細胞毒性作用および炎症反応誘導作用の解析2012

    • Author(s)
      及川(多田)佐枝子、呉ウェンティン、市原学、常杰、矢端将行、及川伸二、市原佐保子
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノサイズ酸化チタンの心肺機能への影響に関する調査研究2012

    • Author(s)
      市原佐保子、小林隆弘、李衛華、尾村誠一、平工雄介、久永直見、丁訓誡、市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] シンポジウム「ナノマテリアルと労働環境衛生」内での報告「欧米のナノマテリアル吸入曝露試験、労働衛生の取り組み」2012

    • Author(s)
      市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] 産業化学物質による神経毒性評価 -最新の動物実験のヒトにおける毒性評価への応用と可能性- (産業中毒・生物的モニタリング研究会企画)2012

    • Author(s)
      市原学
    • Organizer
      第85回日本産業衛生学会
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Oxidative modification leads to the left ventricular dysfunction in cardiomyopathy2012

    • Author(s)
      Sahoko Ichihara, Jie Chang, Saeko Tada-Oikawa, Chisa Ando, Kentaro Kuzuya, Gaku Ichihara, Shinji Oikawa
    • Organizer
      Eurotox 2012(48th congress of European Societies of Toxicology)
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2012 Annual Research Report
  • [Presentation] NAC prevents high-P/Zn-free diet-induced peripheral nervous dysfunction2012

    • Author(s)
      Sahoko Ichihara, Yuka Suzuki, Ai Kato, Takahiro Yamaguchi, Gaku Ichihara
    • Organizer
      Eurotox 2012(48th congress of European Societies of Toxicology)
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2012 Annual Research Report
  • [Presentation] Susceptibility to 1-bromopropane exposure and gene expression in two rat strains2012

    • Author(s)
      Gaku Ichihara, Fen Huang, Sahoko Ichihara, Emiko Kitagawa, Satomi Mizugami, Hitoshi Iwahashi, Iida Mari, Kitoh Junzho
    • Organizer
      Eurotox 2012(48th congress of European Societies of Toxicology)
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2012 Annual Research Report
  • [Presentation] l-bromopropane increases triosephosphate isomerase carbonylation and advanced glycation end-products in the hippocampus of F344 rats2012

    • Author(s)
      Zhenlie HUANG, Sahoko ICHIHARA, Shinji OIKAWA, Jie CHANG, Lingyi ZHANG, Kaviarasan SUBRAMANIAN, Sahabudeen Sheik MOHIDEEN, Gaku ICHIHARA
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Exposure to 1-bromopropane decreases neuron proliferation in adult rat dentate gyrus2012

    • Author(s)
      Lingyi ZHANG, Taku NAGAI, Kiyofumi YAMADA, Sahoko ICHIHARA, Kaviarasan SUBRAMANIAN, Zhenlie HUANG, Sahabudeen Sheik MOHIDEEN, Hisao NAITO, Gaku ICHIHARA
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dispersion method for in vivo safety researches on manufactured nanomaterials2012

    • Author(s)
      Wenting WU, Sahoko ICHIHARA, Saeko TADA-OIKAWA, Jie CHANG, Gaku ICHIHARA
    • Organizer
      The 6th International Congress of Asian Society of Toxicology
    • Place of Presentation
      仙台国際センター(仙台市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Occupational and Environmental Health in Nanotechnology2012

    • Author(s)
      Gaku Ichihara, Takahiro Kobayashi, Kunichi、Miyazawa, Naomi Hisanaga, Kiyoshi Sakai, Eiji Shibata, Ilje Yu, Shinya Toyokuni, Yoshinori Hasegawa, Sahoko Ichihara
    • Organizer
      NANO KOREA 2012 symposium : The 10th International Nanotech Symposium
    • Place of Presentation
      Coex, Seoul, Korea
    • Related Report
      2012 Annual Research Report
  • [Presentation] ANF Technical Seminars on "Nanosafety" Occupational and environmental health in nanotechnology2012

    • Author(s)
      Tsung Tsan SU(Chair), Paul WRIGHT, Gaku ICHIHARA, Sang-Hee SUH, Tsung Tsan SU
    • Organizer
      Asia Nano Forum 9th Summit Meeting(ANFoS2012)
    • Place of Presentation
      Bangkok, Thailand
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kunichi Miyazawa, Dale Porter, Vincet Castranova, Masami Kawaguchi, and Sahoko Ichihara
    • Organizer
      The 6th International Conference on Nanotoxicology
    • Place of Presentation
      20120904-20120907
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cytotoxicity and inflammatory responses induced by nano-sized metal oxide nanoparticles in human monocytic leukemia cells2012

    • Author(s)
      Sahoko Ichihara, Saeko Tada-Oikawa, Masayuki Yabata, Kiyora Izuoka, Jie Chang, Yuka Ota, Wenting Wu, Gaku Ichihara
    • Organizer
      The 6th International Conference on Nanotoxicology
    • Place of Presentation
      Beijin, China
    • Related Report
      2012 Annual Research Report
  • [Presentation] Exposure assessment of manufactured nanomaterials and occupational health survey2012

    • Author(s)
      Gaku ICHIHARA
    • Organizer
      IUMRS-ICEM2012
    • Place of Presentation
      パシフィコ横浜(横浜市)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cytotoxicity induced by nano-sized titanium dioxide in human monocytic leukemia cells(THP-1)2012

    • Author(s)
      Saeko Tada-Oikawa, Sahoko Ichihara, Kiyora Izuoka, Masayuki Yabata, Jie Chang, Yuka Ota, Wenting Wu, Gaku Ichihara
    • Organizer
      IUMRS-ICEM2012
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dispersion Method for Safety Researches on Manufactured Nanomaterials2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kunichi Miyazawa, Dale Porter, Vincet Castranova, Masami Kawaguchi, and Sahoko Ichihara
    • Organizer
      IUMRS-ICEM2012
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Cytotoxicity and inflammatory responses induced by nano-sized titanium dioxide in human monocytic leukemia cells2012

    • Author(s)
      Tada-Oikawa S, Ichihara S, Yabata M, Chang J, Ota Y, Wu W, Ichihara G
    • Organizer
      SENN2012 International Congress on Safety of Engineered Nanoparticles and Nanotechnologies
    • Place of Presentation
      Helsinki, Finland
    • Related Report
      2012 Annual Research Report
  • [Presentation] Effects of short -and long-term exposure to 1-bromopropane on neurogenesis in adult rats2012

    • Author(s)
      Lingyi Zhang, Taku Nagai, Kiyofumi Yamada, Daisuke Ibi, Sahoko Ichihara, Kaviarasan Suburamanian, Zhenlie Huang, Sahabudeen Sheik Mohideen, Hisao Naito, and Gaku Ichihara
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦(神奈川県三浦市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] メタボリック症候群の標的分子マーカーの探索2012

    • Author(s)
      常 杰、市原 学、及川伸二、堀田康弘、加藤智英子、市原佐保子
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦(神奈川県三浦市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] オフセット校正印刷労働者に多発する肝内・肝外胆管癌2012

    • Author(s)
      熊谷信二、車谷典男、市原 学
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦(神奈川県三浦市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] Dispersion method for safety research on manufactured nanomaterials2012

    • Author(s)
      Wenting Wu, Gaku Ichihara, Yuka Suzuki, Kiyora Izuoka, Saeko Oikawa-Tada, Jie Chang, Kiyoshi Sakai, Kunichi Miyazawa, Dale Porter, Vincet Castranova, Masami Kawaguchi, and Sahoko Ichihara
    • Organizer
      日本産業衛生学会第40回産業中毒・生物学的モニタリング研究会
    • Place of Presentation
      マホロバマインズ三浦(神奈川県三浦市)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ブロモプロパンの神経毒性2012

    • Author(s)
      市原学
    • Organizer
      第60回日本職業・災害医学会学術大会
    • Place of Presentation
      大阪国際会議場(大阪市)(招待講演)
    • Related Report
      2012 Annual Research Report
  • [Presentation] ナノマテリアルの安全性

    • Author(s)
      市原学
    • Organizer
      「科学物質・環境規制ワークショップ2013」第5回 ナノマテリアル 安全性と規制化動向
    • Place of Presentation
      北とぴあ、東京・王子市
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] カーボンナノ材料の安全性とリスク管理について

    • Author(s)
      市原 学
    • Organizer
      平成25年度第4回カーボンナノ材料研究会
    • Place of Presentation
      一般財団法人大阪科学技術センタービル、大阪市
    • Related Report
      2013 Annual Research Report
  • [Book] 産業保健マニュアル2013

    • Author(s)
      市原 学、和田攻、森 晃爾
    • Total Pages
      1332
    • Publisher
      南山堂
    • Related Report
      2013 Annual Research Report
  • [Book] 産業安全保健ハンドブック2013

    • Author(s)
      市原 学、小木和孝
    • Total Pages
      415
    • Publisher
      労働科学研究所
    • Related Report
      2013 Annual Research Report

URL: 

Published: 2012-04-24   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi