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Epidemiological study on characteristics and health effects of air pollution in large cities in China

Research Project

Project/Area Number 24406020
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section海外学術
Research Field Hygiene
Research InstitutionHyogo Medical University

Principal Investigator

SHIMA Masayuki  兵庫医科大学, 医学部, 教授 (40226197)

Co-Investigator(Kenkyū-buntansha) 大谷 成人  兵庫医科大学, 医学部, 助教 (10561772)
平木 隆年  (財)ひょうご環境創造協会(兵庫県環境研究センター), その他部局等, 研究員 (60446812)
中坪 良平  (財)ひょうご環境創造協会(兵庫県環境研究センター), その他部局等, 研究員 (60463329)
唐 寧  金沢大学, 学内共同利用施設等, 准教授 (90372490)
Research Collaborator YODA Yoshiko  兵庫医科大学, 医学部, 助教 (80748434)
DONG Lijun  瀋陽市疾病預防控制センター, 所長
FU Wenhua  瀋陽市疾病預防控制センター, 科長
QI Hongye  瀋陽市疾病預防控制センター, 主任医師
GUO Xinbiao  北京大学, 公共衛生学院, 教授
MA Lu  武漢大学, 公共衛生学院, 副教授
Project Period (FY) 2012-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2016: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2013: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2012: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Keywords微小粒子状物質 / 粗大粒子 / 炭素成分 / イオン成分 / 肺機能 / 気道炎症 / 大都市 / 中国 / 国際研究者交流 / 大気汚染 / 粒子状物質 / ガス状物質 / 最大呼気流量 / 呼吸機能 / 1秒量 / 呼吸器症状
Outline of Final Research Achievements

The outdoor and indoor concentrations of airborne fine (PM2.5) and coarse (PM10-2.5) particulate matter were considerably high in Shenyang and Wuhan, China. In particular, the outdoor concentrations of PM2.5 were high due to coal heating in winter. In this study, no association between exposure to air pollutants and decreases in pulmonary function among children was observed. However, an increase in fractional concentration of exhaled nitric oxide (FeNO) among pre-school children significantly associated with mass concentrations of PM2.5 and PM10-2.5, and the concentrations of carbon and many ions in the particles. The association with FeNO and indoor concentrations of PM2.5 and PM10-2.5 was also significant in May and June. These findings suggest the effect of air pollutants on airway inflammation in children.

Report

(6 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • 2013 Annual Research Report
  • 2012 Annual Research Report
  • Research Products

    (47 results)

All 2017 2016 2015 2014 2013 2012 Other

All Int'l Joint Research (2 results) Journal Article (23 results) (of which Int'l Joint Research: 8 results,  Peer Reviewed: 22 results,  Open Access: 3 results,  Acknowledgement Compliant: 3 results) Presentation (21 results) (of which Int'l Joint Research: 1 results,  Invited: 5 results) Book (1 results)

  • [Int'l Joint Research] 武漢大学公共衛生学院/北京大学公共衛生学院/瀋陽市疾病予防対策センター(中国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] 武漢大学公共衛生学院/瀋陽市疾病予防対策センター(中国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Ambient temperature and cardiovascular biomarkers in a repeated-measure study in healthy adults: A novel biomarker index approach.2017

    • Author(s)
      Wu S, Yang D, Pan L, Shan J, Li H, Wei H, Wang B, Huang J, Baccarelli AA, Shima M, Deng F, Guo X.
    • Journal Title

      Environ Res

      Volume: 156 Pages: 231-238

    • DOI

      10.1016/j.envres.2017.02.036

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Chemical constituents and sources of ambient particulate air pollution and biomarkers of endothelial function in a panel of healthy adults in Beijing, China.2016

    • Author(s)
      Wu S, Yang D, Pan L, Shan J, Li H, Wei H, Wang B, Huang J, Baccarelli AA, Shima M, Deng F, Guo X.
    • Journal Title

      Sci Total Environ.

      Volume: 560-561 Pages: 141-149

    • DOI

      10.1016/j.scitotenv.2016.03.228

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Acute effects on pulmonary function in young healthy adults exposed to traffic-related air pollution in semi-closed transport hub in Beijing2016

    • Author(s)
      Huang J, Deng F, Wu S, Zhao Y, Shima M, Guo B, Liu Q, Guo X.
    • Journal Title

      Environ Health Prev Med.

      Volume: 21 Issue: 5 Pages: 312-320

    • DOI

      10.1007/s12199-016-0531-5

    • NAID

      50012009981

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Short-term exposure to high ambient air pollution increases airway inflammation and respiratory symptoms in chronic obstructive pulmonary disease patients in Beijing, China.2016

    • Author(s)
      Wu S, Ni Y, Li H, Pan L, Yang D, Baccarelli AA, Deng F, Chen Y, Shima M, Guo X.
    • Journal Title

      Environ Int

      Volume: 94 Pages: 76-82

    • DOI

      10.1016/j.envint.2016.05.004

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Ambient particulate air pollution and circulating antioxidant enzymes: A repeated-measure study in healthy adults in Beijing, China2016

    • Author(s)
      Wu S, Wang B, Yang D, Wei H, Li H, Pan L, Huang J, Wang X, Qin Y, Zheng C, Shima M, Deng F, Guo X
    • Journal Title

      Environ Pollut

      Volume: 208 Pages: 16-24

    • DOI

      10.1016/j.envpol.2015.06.002

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 中国における大気汚染の健康影響に関する共同研究2016

    • Author(s)
      島正之,余田佳子
    • Journal Title

      大気環境学会誌

      Volume: 51 Pages: 25-8

    • NAID

      130005163182

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Short-term effects of fine particulate matter and temperature on lung function among healthy college students in Wuhan, China2015

    • Author(s)
      Zhang Y, He M, Wu S, Zhu Y, Wang S, Shima M, Tamura K, Ma L.
    • Journal Title

      Int J Environ Res Public Health

      Volume: 12 Issue: 7 Pages: 7777-93

    • DOI

      10.3390/ijerph120707777

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Does ambient temperature interact with air pollution to alter blood pressure? A repeated-measure study in healthy adults2015

    • Author(s)
      Wu S, Deng F, Huang J, Wang X, Qin Y, Zheng C, Wei H, Shima M, Guo X
    • Journal Title

      J Hypertens

      Volume: 33 Issue: 12 Pages: 2414-21

    • DOI

      10.1097/hjh.0000000000000738

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Association of chemical constituents and pollution sources of ambient fine particulate air pollution and biomarkers of oxidative stress associated with atherosclerosis: A panel study among young adults in Beijing, China2015

    • Author(s)
      Wu S, Yang D, Wei H, Wang B, Huang J, Li H, Shima M, Deng F, Guo X
    • Journal Title

      Chemosphere

      Volume: 135 Pages: 347-53

    • DOI

      10.1016/j.chemosphere.2015.04.096

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Atmospheric behaviors of polycyclic aromatic hydrocarbons at a Japanese remote background site, Noto peninsula, from 2004 to 20142015

    • Author(s)
      Tang N, Hakamata M, Sato K, Okada Y, Yang XY, Tatematsu M, Toriba A, Kameda T, Hayakawa K.
    • Journal Title

      Atmos Environ

      Volume: 120 Pages: 144-51

    • DOI

      10.1016/j.atmosenv.2015.08.090

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fine particulate matter, temperature, and lung function in healthy adults: Findings from the HVNR study.2014

    • Author(s)
      Wu S, Deng F, Hao Y, Wang X, Zheng C, Lv H, Lu X, Wei H, Huang J, Qin Y, Shima M, Guo X.
    • Journal Title

      Chemosphere

      Volume: 108 Pages: 168-174

    • DOI

      10.1016/j.chemosphere.2014.01.032

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Atmospheric Behaviors of Polycyclic Aromatic Hydrocarbons in East Asia2014

    • Author(s)
      Hayakawa, K., Tang, N., Kameda, T., Toriba, A.
    • Journal Title

      Genes and Environment

      Volume: 36 Issue: 3 Pages: 152-159

    • DOI

      10.3123/jemsge.2014.016

    • NAID

      130004943665

    • ISSN
      1880-7046, 1880-7062
    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 大気汚染のアレルギー疾患への影響に関する疫学的知見2014

    • Author(s)
      島 正之
    • Journal Title

      アレルギー

      Volume: 63 Pages: 891-900

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 日本における微小粒子状物質(PM2.5)の健康影響に関する疫学研究2014

    • Author(s)
      島 正之
    • Journal Title

      日中医学

      Volume: 29 Pages: 15-19

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Association between PM2.5 and primary care visits due to asthma attack in Japan: relation to Beijing's air pollution episode in January 2013.2014

    • Author(s)
      Yamazaki S, Shima M, Yoda Y, Oka K, Kurosaka F, Shimizu S, Takahashi H, Nakatani Y, Nishikawa J, Fujiwara K, Mizumori Y, Mogami A, Yamada T, Yamamoto N.
    • Journal Title

      Environ Health Prev Med.

      Volume: 19 Issue: 2 Pages: 172-176

    • DOI

      10.1007/s12199-013-0371-5

    • NAID

      210000000310

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of cardiopulmonary health effects with source-appointed ambient fine particulate in Beijing, China: a combined analysis from the Healthy Volunteer Natural Relocation (HVNR) study.2014

    • Author(s)
      Wu S, Deng F, Wei H, Huang J, Wang X, Hao Y, Zheng C, Qin Y, Lv H, Shima M, Guo X.
    • Journal Title

      Environ. Sci. Technol.

      Volume: 48 Issue: 6 Pages: 3438-3448

    • DOI

      10.1021/es404778w

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Blood pressure changes and chemical constituents of particulate air pollution: results from the healthy volunteer natural relocation (HVNR) study.2013

    • Author(s)
      Wu S, Deng F, Huang J, Wang H, Shima M, Wang X, Qin Y, Zheng C, Wei H, Hao Y, Lv H, Lu X, Guo X.
    • Journal Title

      Environ Health Perspect.

      Volume: 121 Issue: 1 Pages: 66-72

    • DOI

      10.1289/ehp.1104812

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemical constituents of fine particulate air pollution and pulmonary function in healthy adults: The Healthy Volunteer Natural Relocation study.2013

    • Author(s)
      Wu S, Deng F, Hao Y, Shima M, Wang X, Zheng C, Wei H, Lv H, Lu X, Huang J, Qin Y, Guo X.
    • Journal Title

      J Hazard Mater

      Volume: 260 Pages: 183-191

    • DOI

      10.1016/j.jhazmat.2013.05.018

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Association of lung function in a panel of young healthy adults with various chemical components of ambient fine particulate air pollution in Beijing, China.2013

    • Author(s)
      Wu S, Deng F, Wang X, Wei H, Shima M, Huang J, Lv H, Hao Y, Zheng C, Qin Y, Lu X, Guo X.
    • Journal Title

      Atmos Environ.

      Volume: 77 Pages: 873-874

    • DOI

      10.1016/j.atmosenv.2013.06.018

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The short-term effects of particulate matter on lung function of college students in autumn and winter in Wuhan.2013

    • Author(s)
      Li JY, Ma L, Liu LZ, Zhou J, He MQ, Shima M, Tamura K.
    • Journal Title

      Zhonghua Yu Fang Yi Xue Za Zhi

      Volume: 47 Pages: 155-159

    • Related Report
      2013 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Temperature, traffic-related air pollution, and heart rate variability in a panel of healthy adults2013

    • Author(s)
      Wu S, et al.
    • Journal Title

      Environ Res

      Volume: 120 Pages: 82-89

    • DOI

      10.1016/j.envres.2012.08.008

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemical constituents of ambient particulate air pollution and biomarkers of inflammation, coagulation and homocysteine in healthy adults : A prospective panel study2012

    • Author(s)
      Wu S, et al.
    • Journal Title

      Part Fibre Toxicol

      Volume: 9 Issue: 1 Pages: 49-49

    • DOI

      10.1186/1743-8977-9-49

    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Journal Article] On-Line Concentration and Fluorescence Determination HPLC for Polycyclic Aromatic Hydrocarbons in Seawater Samples and Its Application to Japan Sea2012

    • Author(s)
      Li Ying
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 60 Issue: 4 Pages: 531-535

    • DOI

      10.1248/cpb.60.531

    • NAID

      130001852445

    • ISSN
      0009-2363, 1347-5223
    • Related Report
      2012 Annual Research Report
    • Peer Reviewed
  • [Presentation] 中国武漢市における大気汚染の幼児の呼吸器系への急性影響2017

    • Author(s)
      余田 佳子,馬 露,中坪 良平,堀江 洋祐,平木 隆年,島 正之
    • Organizer
      第87回日本衛生学会学術総会
    • Place of Presentation
      フェニックスシーガイアリゾート(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 小児の呼吸器系に対する大気汚染の影響2016

    • Author(s)
      島 正之
    • Organizer
      第49回日本小児呼吸器学会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2016-10-28
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] GC-MS/MSによる大気粉塵中多環芳香族炭化水素キノン類の発生源評価2016

    • Author(s)
      本間千春,宇於崎和香,北 将大,唐 寧,早川和一,鳥羽 陽
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 中国・北京市の2004年以降の大気中多環芳香族炭化水素類の追跡2015

    • Author(s)
      早川和一,唐 寧,鳥羽 陽
    • Organizer
      第56回大気環境学会年会
    • Place of Presentation
      早稲田大学西早稲田キャンパス(東京都)
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 中国瀋陽市のタクシー車内で携帯型ナノ粒子サンプラにより捕集した大気中ナノ粒子に含まれる多環芳香族炭化水素類の解析2015

    • Author(s)
      鳥羽 陽,加賀野井祐一,比嘉志歩,唐 寧,符 文華,斉 宏業,畑 光彦,古内正美,早川和一
    • Organizer
      第56回大気環境学会年会
    • Place of Presentation
      早稲田大学西早稲田キャンパス(東京都)
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] Temporal variation of particulate polycyclic aromatic hydrocarbon concentrations in Northeast Asia2015

    • Author(s)
      Inomata Y, Kajino M, Sato K, Kurokawa J, Hayakawa K, Tang N, Kameda T, Ohara T, Ueda H
    • Organizer
      9th Asian Aerosol Conference
    • Place of Presentation
      Kanazawa Tokyu Hotel (Ishikawa, Kanazawa)
    • Year and Date
      2015-06-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] PM2.5をはじめとする大気汚染の健康影響と対策2015

    • Author(s)
      島正之
    • Organizer
      第14回日本旅行医学大会
    • Place of Presentation
      国立オリンピック記念青少年総合センター(東京都)
    • Year and Date
      2015-04-19
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 中国瀋陽市における大気環境及びPM2.5個人暴露濃度の実態把握2015

    • Author(s)
      中坪良平、平木隆年、唐寧、符文華、斉宏業、余田佳子、島正之
    • Organizer
      平成26年度大気環境学会近畿支部エアロゾル部会講演会
    • Place of Presentation
      大阪市
    • Year and Date
      2015-03-06
    • Related Report
      2014 Annual Research Report
  • [Presentation] 中国瀋陽市におけるPM2.5個人暴露濃度の実態把握に関する研究2015

    • Author(s)
      中坪良平、平木隆年、唐寧、符文華、斉宏業、余田佳子、島正之
    • Organizer
      第29回全国環境研協議会東海・近畿・北陸支部研究会
    • Place of Presentation
      四日市市
    • Year and Date
      2015-01-15
    • Related Report
      2014 Annual Research Report
  • [Presentation] 中国瀋陽市のタクシー車内における携帯型ナノ粒子サンプラーを用いた大気中のナノ粒子捕集と多環芳香族炭化水素類の分析2014

    • Author(s)
      比嘉志歩,加賀野井祐一,唐寧,符文華,斉宏業,畑光彦,古内正美,早川和一,鳥羽陽
    • Organizer
      日本薬学会北陸支部第126回例会
    • Place of Presentation
      金沢市
    • Year and Date
      2014-11-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] Exposure Assessment of Taxi Drivers to Environmental Nanoparticles in Shenyang, China.2014

    • Author(s)
      Toriba, A., Kaganoi, Y., Tang, N., Fu, W., Qi, H., Hata, M., Furuuchi, M., Hayakawa, K.
    • Organizer
      2014 International Society of Exposure Science 24th Annual Meeting
    • Place of Presentation
      Cincinnati, OH, USA
    • Year and Date
      2014-10-12 – 2014-10-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 中国・瀋陽市のタクシー車内で捕集した環境ナノ粒子中の多環芳香族炭化水素類の測定2014

    • Author(s)
      鳥羽陽,加賀野井祐一,唐寧,符文華,斉宏業,畑 光彦,古内正美
    • Organizer
      第55回大気環境学会年会
    • Place of Presentation
      松山市
    • Year and Date
      2014-09-17 – 2014-09-19
    • Related Report
      2014 Annual Research Report
  • [Presentation] 中国・瀋陽市におけるタクシー運転手の環境ナノ粒子曝露調査2014

    • Author(s)
      鳥羽 陽,加賀野井祐一,唐寧,符文華,斉宏業,畑光彦,古内正美,早川和一
    • Organizer
      第23回環境化学討論会
    • Place of Presentation
      京都市
    • Year and Date
      2014-05-14 – 2014-05-16
    • Related Report
      2014 Annual Research Report
  • [Presentation] 中国における大気汚染の健康影響に関する疫学研究2013

    • Author(s)
      島正之
    • Organizer
      第83回日本衛生学会学術総会
    • Place of Presentation
      金沢市(招待講演)
    • Year and Date
      2013-03-25
    • Related Report
      2012 Annual Research Report
  • [Presentation] 東アジアの都市における大気中多環芳香族炭化水素類の汚染とその推移2012

    • Author(s)
      唐寧, 他
    • Organizer
      日本分析化学会第61年会
    • Place of Presentation
      金沢市(招待講演)
    • Year and Date
      2012-09-20
    • Related Report
      2012 Annual Research Report
  • [Presentation] Health effects of regional air pollution in Japan2012

    • Author(s)
      Shima M
    • Organizer
      Korea-Ch ina-Japan Symposium on Air Quality Management Policy of Larce Cities
    • Place of Presentation
      Suncheon, Korea(招待講演)
    • Year and Date
      2012-07-19
    • Related Report
      2012 Annual Research Report
  • [Presentation] Airborne particulate matter and respiratory diseases in Japan

    • Author(s)
      Shima M
    • Organizer
      18th Congress of the Asian Pacific Society of Respirology
    • Place of Presentation
      Yokohama
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Effects of particulate air pollution on respiratory symptoms and pulmonary function in Japan

    • Author(s)
      Shima M
    • Organizer
      45th Annual Conference Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Wuhan, China
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] Epidemiological studies on health effects of PM 2.5 in Japan

    • Author(s)
      Shima M
    • Organizer
      54th Annual Meeting of Japan Society for Atomospheric Environment
    • Place of Presentation
      Niigata
    • Related Report
      2013 Annual Research Report
    • Invited
  • [Presentation] The short-term effects of particulate matter on lung function of college students in autum and winter in Wuhan

    • Author(s)
      Zhang Y, Ma L, Ki, J, Shima M, Amura K
    • Organizer
      45th Annual Conference Asia-Pacific Academic Consortium for Public Health
    • Place of Presentation
      Wuhan, China
    • Related Report
      2013 Annual Research Report
  • [Presentation] Characteristics of outdoor atmospheric pollutants in autumn and winter in Shenyang, China

    • Author(s)
      Huang C, Tang N, Yoda Y, Shima M
    • Organizer
      54th Annual Meeting of Japan Society for Atomospheric Environment
    • Place of Presentation
      Niigata
    • Related Report
      2013 Annual Research Report
  • [Book] 知っておきたいPM 2.5の基礎知識2013

    • Author(s)
      島 正之
    • Total Pages
      90
    • Publisher
      一般財団法人 日本環境衛生センター
    • Related Report
      2013 Annual Research Report

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Published: 2012-04-24   Modified: 2019-07-29  

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