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Spatio-temporal analysis of intrinsic dynamics in cortical activities

Research Project

Project/Area Number 24500286
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Sensitivity informatics/Soft computing
Research InstitutionKyoto Sangyo University

Principal Investigator

ITO Hiroyuki  京都産業大学, コンピュータ理工学部, 教授 (80201929)

Co-Investigator(Kenkyū-buntansha) MARUYAMA Yoshiko  京都産業大学, コンピュータ理工学部, 講師 (80723353)
Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2012: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords視覚皮質 / 発火数相関 / 時空間活動 / 刺激依存性 / 試行間変動性 / 変動性 / spike count correlation / 多細胞データ / 自発発火 / 相関
Outline of Final Research Achievements

We performed multi-neuron recordings on the cat visual cortex and found that the population mean of the spike count correlation did not necessarily represent the nature of correlated variabilities because the spike count correlation showed significant diversity and heterogeneity. Although the population mean was relatively small (0.06), the correlations of individual unit pairs were distributed over a broad range, extending to both positive and negative values. In most of the recording sessions of local cell populations (83%), significantly positive correlations coexisted with significantly negative ones in different unit pairs. Furthermore, nearly 20% of the unit pairs showed significant variation in the spike count correlation for different stimulus orientations. Diversity, heterogeneity and context dependent variation suggests that the correlated spike count variabilities originate not from fixed anatomical connections but rather from the dynamic interaction of neuronal networks.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (7 results)

All 2014 2013 2012

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (5 results) (of which Invited: 2 results)

  • [Journal Article] 「意味の無い」脳科学のススメ2014

    • Author(s)
      伊藤浩之
    • Journal Title

      日本神経回路学会誌

      Volume: 21 Pages: 43-49

    • NAID

      130004679140

    • Related Report
      2014 Annual Research Report
  • [Journal Article] Diversity, heterogeneity and orientation-dependent variation of spike count correlation in the cat visual cortex.2013

    • Author(s)
      Y. Maruyama and H.Ito
    • Journal Title

      Eur. J. Neurosci.

      Volume: 38 Issue: 11 Pages: 3611-3627

    • DOI

      10.1111/ejn.12363

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Diversity, heterogeneity and orientation dependent variation of spike count correlation in cat visual cortex.2013

    • Author(s)
      H.Ito and Y. Maruyama
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Design of multi-electrode array for homogeneous samplings of differently orientation tuned unit population in cat visual cortex.2013

    • Author(s)
      Y. Maruyama and H. Ito
    • Organizer
      Neuroscience 2013
    • Place of Presentation
      San Diego, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] What spontaneous activities tell us about the brain?2013

    • Author(s)
      H. Ito
    • Organizer
      神経科学と統計科学の対話3
    • Place of Presentation
      統計数理研究所
    • Related Report
      2012 Research-status Report
    • Invited
  • [Presentation] Design of multi-electrode array for homogeneous samplings of differently orientation tuned unit population2013

    • Author(s)
      Y. Maruyama and H. Ito
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      京都国際会議場
    • Related Report
      2012 Research-status Report
  • [Presentation] Correlated spike count variabilities in visual cortex and their stimulus dependence2012

    • Author(s)
      H. Ito
    • Organizer
      Workshop on statistical aspect of neural coding
    • Place of Presentation
      Kyoto University & Ritsumei University
    • Related Report
      2012 Research-status Report
    • Invited

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Published: 2013-05-31   Modified: 2025-11-19  

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