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Comprehensive analyses to understand genetic variant data and its development.

Research Project

Project/Area Number 24500337
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Statistical science
Research InstitutionTokyo Medical and Dental University

Principal Investigator

TOMITA MAKOTO  東京医科歯科大学, 医学部附属病院, 准教授 (20399025)

Project Period (FY) 2012-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2012: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
KeywordsSNPデータ / 関連解析 / 空間疫学 / 保健精神データ / 集積性の検出 / 遺伝子多様性 / ゲノムワイド関連解析 / 連鎖不平衡 / ハプロタイプ / 多変量QTL解析 / 遺伝統計学 / 集積性 / 空間統計学 / SNP解析 / 空間集積性
Outline of Final Research Achievements

For SNP data that is major marker on DNA data, we focus to identify LD block using Echelon analysis, then we got our original solution. Second, we discussed to apply Echelon analysis for gene-network data. Third, we applied the above method to Public Health data, then we got an important result.

Report

(4 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • 2013 Research-status Report
  • 2012 Research-status Report
  • Research Products

    (15 results)

All 2015 2014 2013 2012

All Journal Article (9 results) (of which Peer Reviewed: 9 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (6 results) (of which Invited: 3 results)

  • [Journal Article] Spatial clustering properties in the temporal variation of suicide rates/numbers among Japanese citizens: A comprehensive comparison and discussion2015

    • Author(s)
      Makoto TOMITA, Takafumi KUBOTA and Fumio ISHIOKA
    • Journal Title

      PLoS ONE

      Volume: 1 Issue: 7 Pages: e0127358-e0127358

    • DOI

      10.1371/journal.pone.0127358

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Focusing Approach Using LD Block and Association Study with Haplotype Combination on DNA Data2014

    • Author(s)
      Makoto TOMITA
    • Journal Title

      Proceedings 2013 Eleventh International Conference on ICT and Knowledge Engineering

      Volume: 1 Pages: 5-10

    • DOI

      10.1109/ictke.2013.6756266

    • Related Report
      2014 Annual Research Report 2013 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] ハプロタイプ解析における推定・ブロック同定および関連解析2013

    • Author(s)
      冨田 誠
    • Journal Title

      計算機統計学

      Volume: 25 Pages: 53-68

    • NAID

      110009562765

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Long-term Results of Brachytherapy in Early Mobile Tongue Cancer with 10-Year Minimal Follow-up2013

    • Author(s)
      Mais M. ABDALMEAR, Makoto TOMITA and Hitoshi SHIBUYA
    • Journal Title

      Anticancer Research

      Volume: 33 Pages: 317-324

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Posterior cerebral artery laterality on MRA predicts long-term functional outcome in middle cerebral artery occlusion2013

    • Author(s)
      Ichijo M
    • Journal Title

      Stroke

      Volume: 44 Issue: 2 Pages: 512-515

    • DOI

      10.1161/strokeaha.112.674101

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Visual Reproduction on the Wechsler Memory Scale-Revised as a Predictor of Alzheimer's Disease in Japanese Patients with Mild Cognitive Impairments2013

    • Author(s)
      Takumi HORI, Nobuo SANJO, Makoto TOMITA and Hidehiro MIZUSAWA
    • Journal Title

      Dementia and Geriatric Cognitive Disorders

      Volume: 35 Issue: 3-4 Pages: 165-176

    • DOI

      10.1159/000346738

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quantitative analyses of high-resolution 3D MR images of highly myopic eyes to determine their shapes2012

    • Author(s)
      Muka MORIYAMA, Kyoko OHNO-MATSUI, Toshio MODEGI, Junichi KONDO, Yoichi TAKAHASHI, Makoto TOMITA, Takashi TOKORO and Ikuo MORITA
    • Journal Title

      Investigative Ophthalmology and Visual Science

      Volume: 53 Issue: 8 Pages: 4510-4518

    • DOI

      10.1167/iovs.12-9426

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] Association between shape of sclera and myopic retinochoroidal lesions in patients with pathologic myopia.2012

    • Author(s)
      Ohno-Matsui K
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 53 Issue: 10 Pages: 6046-6061

    • DOI

      10.1167/iovs.12-10161

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Journal Article] ハプロタイプ解析における推定・ブロック同定および関連解析2012

    • Author(s)
      冨田 誠
    • Journal Title

      計算機統計学

      Volume: 25 Pages: 53-68

    • NAID

      110009562765

    • Related Report
      2012 Research-status Report
    • Peer Reviewed
  • [Presentation] 遺伝・精神保健データに対する集積性手法の実践2014

    • Author(s)
      冨田 誠, 石岡 文生, 久保田 貴文, 西山 毅, 栗原 考次
    • Organizer
      2014年度統計関連学会連合大会
    • Place of Presentation
      東京大学
    • Year and Date
      2014-09-13 – 2014-09-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Identify LD Blocks Using Biplot Function Method2013

    • Author(s)
      Makoto TOMITA, Kuniyoshi HAYASHI and Koji Kurihara
    • Organizer
      European Human Genetics Conferences 2013
    • Place of Presentation
      Paris, France
    • Related Report
      2013 Research-status Report
  • [Presentation] Comparison of Spatial Clusters between Suicide Data and Its Increase-decrease Rates in Japan2013

    • Author(s)
      Makoto TOMITA, Takafumi KUBOTA, Fumio ISHIOKA and Toshiharu FUJITA
    • Organizer
      Conference of the International Federation of Classication Societies (IFCS-2013)
    • Place of Presentation
      Tilburg, Netherlands
    • Related Report
      2013 Research-status Report
  • [Presentation] 空間集積性の手法を利用した遺伝データへの応用2013

    • Author(s)
      石岡文生, 冨田 誠
    • Organizer
      2013年度統計関連学会連合大会
    • Place of Presentation
      大阪大学
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Comparison among spatial clustering methods on hierarchical structures for DNA markers2012

    • Author(s)
      Makoto TOMITA
    • Organizer
      COMPSTAT2012
    • Place of Presentation
      Limassol, Cyprus
    • Related Report
      2012 Research-status Report
  • [Presentation] Association Study and Comprehended Hierarchical Structures on DNA Markers2012

    • Author(s)
      Makoto TOMITA and Koji Kurihara
    • Organizer
      JCS-CLADAG2012
    • Place of Presentation
      Anacapri, Italy
    • Related Report
      2012 Research-status Report
    • Invited

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Published: 2013-05-31   Modified: 2019-07-29  

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