Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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Outline of Final Research Achievements |
In this study we have investigated how early auditory experience shapes the neuronal circuits during the zebra finch bird song learning. We recorded the auditory neuronal responses to varieties of song stimulation, before, during and after sensory song learning, and found that a subset of neurons secondary auditory cortex become to show exclusive responses to learned father songs. Moreover neurons decreased selectivity to the learned song by blocking of GABA inhibitory circuit by local injection of GABA receptor antagonist, gabazine. Those suggest early auditory experience in the developmental critical period recruits GABA inhibitory circuits in the auditory association cortex, which lead to sparse memory auditory father experience. formed in a subset of neurons.
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