| Project/Area Number |
24500460
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | Osaka University |
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Principal Investigator |
SATO HIROMICHI 大阪大学, 医学(系)研究科(研究院), 教授 (50154092)
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| Co-Investigator(Renkei-kenkyūsha) |
SAWAI Hjime. 大阪大学, 大学院医学系研究科, 准教授 (20202103)
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| Project Period (FY) |
2012-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2012: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 初期視覚系 / 刺激文脈依存的反応修飾 / 網膜神経節細胞 / 外側膝状体 / 一次視覚野 / 古典的受容野 / 受容野周囲抑制 / 刺激特徴選択性 / 視覚系 / 受容野 / 文脈依存的反応修飾 / ネコ / 活動相互相関解析 / 刺激方位 / 空間周波数 |
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| Outline of Final Research Achievements |
The response magnitudes of neurons in the early visual system, i.e., retina-LGN-V1, is modulated according to the figural-properties of visual stimuli within and outside the receptive field (contextual modulation). To clarify the circuit mechanism of the contextual modulation, I conducted electrophysiological analysis using anesthetized cats. The results are summarized as follows; 1)The contextual modulation started from the retina and became stronger in the further stages. 2) In the neural circuit showing a functional connection, exhibiting the firing correlation, neurons in the different processing stages shared similar stimulus-tuning properties for the modulation. And, 3) The results so far suggested both bottom-up and top-down mechanisms.
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