| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2012: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
|
|---|
| Outline of Final Research Achievements |
Central synaptic transmission is regulated by various molecules on the surface of cell membranes as well as in the cytosoles. In the present grant project, I have clarified 1) modulatory roles of intracellular muscarinic receptor M1 subtype in the regulation of long term potentiation in the hippocampal excitatory synaptic transmission, 2) functions of physiologically released dopamine in the inhibitory synapse and neuronal activities in the striatum, 3) presynaptic inhibition of inhibitory synaptic transmission in the basal forebrain by serotonin 5-HT1B receptors. I'm also analyzing the functions of intracellular transcription factors in the excitatory anｄ inhibitory transmission in the striatum.
|
